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Metergoline inhibits the neuronal Nav1.2 voltage-dependent Na(+) channels expressed in Xenopus oocytes.

Lee JH, Liu J, Shin M, Hong M, Nah SY, Bae H.

Acta Pharmacol Sin. 2014 Jul;35(7):862-8. doi: 10.1038/aps.2014.30. Epub 2014 Jun 9.


The endocannabinoid anandamide inhibits voltage-gated sodium channels Nav1.2, Nav1.6, Nav1.7, and Nav1.8 in Xenopus oocytes.

Okura D, Horishita T, Ueno S, Yanagihara N, Sudo Y, Uezono Y, Sata T.

Anesth Analg. 2014 Mar;118(3):554-62. doi: 10.1213/ANE.0000000000000070.


Regulation of Human Kv1.4 Channel Activity by the Antidepressant Metergoline.

Yeom HD, Lee JH.

Biol Pharm Bull. 2016;39(6):1069-72. doi: 10.1248/bpb.b16-00069.


Blocking effect of methylflavonolamine on human Na(V)1.5 channels expressed in Xenopus laevis oocytes and on sodium currents in rabbit ventricular myocytes.

Fan XR, Ma JH, Zhang PH, Xing JL.

Acta Pharmacol Sin. 2010 Mar;31(3):297-306. doi: 10.1038/aps.2010.8. Epub 2010 Feb 22.


Neurosteroids allopregnanolone sulfate and pregnanolone sulfate have diverse effect on the α subunit of the neuronal voltage-gated sodium channels Nav1.2, Nav1.6, Nav1.7, and Nav1.8 expressed in xenopus oocytes.

Horishita T, Yanagihara N, Ueno S, Sudo Y, Uezono Y, Okura D, Minami T, Kawasaki T, Sata T.

Anesthesiology. 2014 Sep;121(3):620-31. doi: 10.1097/ALN.0000000000000296.


Effects of dextrorotatory morphinans on brain Na+ channels expressed in Xenopus oocytes.

Lee JH, Shin EJ, Jeong SM, Lee BH, Yoon IS, Lee JH, Choi SH, Kim YH, Pyo MK, Lee SM, Chae JS, Rhim H, Oh JW, Kim HC, Nah SY.

Eur J Pharmacol. 2007 Jun 14;564(1-3):7-17. Epub 2007 Feb 16.


Characteristics of ginsenoside Rg3-mediated brain Na+ current inhibition.

Lee JH, Jeong SM, Kim JH, Lee BH, Yoon IS, Lee JH, Choi SH, Kim DH, Rhim H, Kim SS, Kim JI, Jang CG, Song JH, Nah SY.

Mol Pharmacol. 2005 Oct;68(4):1114-26. Epub 2005 Jul 13.


Differential modulation of Nav1.7 and Nav1.8 peripheral nerve sodium channels by the local anesthetic lidocaine.

Chevrier P, Vijayaragavan K, Chahine M.

Br J Pharmacol. 2004 Jun;142(3):576-84. Epub 2004 May 17.


Inhibition by pregnenolone sulphate, a metabolite of the neurosteroid pregnenolone, of voltage-gated sodium channels expressed in Xenopus oocytes.

Horishita T, Ueno S, Yanagihara N, Sudo Y, Uezono Y, Okura D, Sata T.

J Pharmacol Sci. 2012;120(1):54-8. Epub 2012 Aug 8.


Inhibition of voltage-gated Na⁺ channels by the synthetic cannabinoid ajulemic acid.

Foadi N, Berger C, Pilawski I, Stoetzer C, Karst M, Haeseler G, Wegner F, Leffler A, Ahrens J.

Anesth Analg. 2014 Jun;118(6):1238-45. doi: 10.1213/ANE.0000000000000188.


Comparison of the effects of antiarrhythmic drugs flecainide and verapamil on fKv1.4ΔN channel currents in Xenopus oocytes.

Chen H, Zhang D, Chao SP, Ren JH, Xu L, Jiang XJ, Wang SM.

Acta Pharmacol Sin. 2013 Feb;34(2):221-30. doi: 10.1038/aps.2012.157. Epub 2012 Dec 3.


Voltage-dependent blockade by bupivacaine of cardiac sodium channels expressed in Xenopus oocytes.

Zhang H, Ji H, Liu Z, Ji Y, You X, Ding G, Cheng Z.

Neurosci Bull. 2014 Aug;30(4):697-710. doi: 10.1007/s12264-013-1449-1. Epub 2014 Jul 9.


Isoform-selective effects of isoflurane on voltage-gated Na+ channels.

OuYang W, Hemmings HC Jr.

Anesthesiology. 2007 Jul;107(1):91-8.


Lidocaine block of neonatal Nav1.3 is differentially modulated by co-expression of beta1 and beta3 subunits.

Lenkowski PW, Shah BS, Dinn AE, Lee K, Patel MK.

Eur J Pharmacol. 2003 Apr 25;467(1-3):23-30.


Fast-onset lidocaine block of rat NaV1.4 channels suggests involvement of a second high-affinity open state.

Gingrich KJ, Wagner LE 2nd.

Biochim Biophys Acta. 2016 Jun;1858(6):1175-88. doi: 10.1016/j.bbamem.2016.02.033. Epub 2016 Feb 27.


Independent and joint modulation of rat Nav1.6 voltage-gated sodium channels by coexpression with the auxiliary β1 and β2 subunits.

Tan J, Soderlund DM.

Biochem Biophys Res Commun. 2011 Apr 22;407(4):788-92. doi: 10.1016/j.bbrc.2011.03.101. Epub 2011 Mar 31.


Modulation of Nav1.7 and Nav1.8 peripheral nerve sodium channels by protein kinase A and protein kinase C.

Vijayaragavan K, Boutjdir M, Chahine M.

J Neurophysiol. 2004 Apr;91(4):1556-69. Epub 2003 Dec 3.


Mefloquine inhibits voltage dependent Nav1.4 channel by overlapping the local anaesthetic binding site.

Paiz-Candia B, Islas AA, Sánchez-Solano A, Mancilla-Simbro C, Scior T, Millan-PerezPeña L, Salinas-Stefanon EM.

Eur J Pharmacol. 2017 Feb 5;796:215-223. doi: 10.1016/j.ejphar.2017.01.002. Epub 2017 Jan 3.


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