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Items: 1 to 20 of 91

1.

Profiling the orphan enzymes.

Sorokina M, Stam M, Médigue C, Lespinet O, Vallenet D.

Biol Direct. 2014 Jun 6;9:10. doi: 10.1186/1745-6150-9-10. Review.

2.

A survey of orphan enzyme activities.

Pouliot Y, Karp PD.

BMC Bioinformatics. 2007 Jul 10;8:244.

3.

'Unknown' proteins and 'orphan' enzymes: the missing half of the engineering parts list--and how to find it.

Hanson AD, Pribat A, Waller JC, de Crécy-Lagard V.

Biochem J. 2009 Dec 14;425(1):1-11. doi: 10.1042/BJ20091328. Review.

4.

ORENZA: a web resource for studying ORphan ENZyme activities.

Lespinet O, Labedan B.

BMC Bioinformatics. 2006 Oct 6;7:436.

5.

The CanOE strategy: integrating genomic and metabolic contexts across multiple prokaryote genomes to find candidate genes for orphan enzymes.

Smith AA, Belda E, Viari A, Medigue C, Vallenet D.

PLoS Comput Biol. 2012 May;8(5):e1002540. doi: 10.1371/journal.pcbi.1002540. Epub 2012 May 31.

6.

Puzzling over orphan enzymes.

Lespinet O, Labedan B.

Cell Mol Life Sci. 2006 Mar;63(5):517-23. Review.

PMID:
16465439
7.

Automatic selection of reference taxa for protein-protein interaction prediction with phylogenetic profiling.

Simonsen M, Maetschke SR, Ragan MA.

Bioinformatics. 2012 Mar 15;28(6):851-7. doi: 10.1093/bioinformatics/btr720. Epub 2012 Jan 4.

PMID:
22219205
8.

Distribution of orphan metabolic activities.

Chen L, Vitkup D.

Trends Biotechnol. 2007 Aug;25(8):343-8. Epub 2007 Jun 18.

PMID:
17580095
9.

Widespread recruitment of ancient domain structures in modern enzymes during metabolic evolution.

Kim HS, Mittenthal JE, Caetano-Anollés G.

J Integr Bioinform. 2013 Feb 14;10(1):214. doi: 10.2390/biecoll-jib-2013-214.

PMID:
23406778
10.

Orphan enzymes could be an unexplored reservoir of new drug targets.

Lespinet O, Labedan B.

Drug Discov Today. 2006 Apr;11(7-8):300-5. Review.

PMID:
16580971
11.

DETECT--a density estimation tool for enzyme classification and its application to Plasmodium falciparum.

Hung SS, Wasmuth J, Sanford C, Parkinson J.

Bioinformatics. 2010 Jul 15;26(14):1690-8. doi: 10.1093/bioinformatics/btq266. Epub 2010 May 30.

PMID:
20513663
12.

The phylogenetic extent of metabolic enzymes and pathways.

Peregrin-Alvarez JM, Tsoka S, Ouzounis CA.

Genome Res. 2003 Mar;13(3):422-7.

13.

Rapid identification of sequences for orphan enzymes to power accurate protein annotation.

Ramkissoon KR, Miller JK, Ojha S, Watson DS, Bomar MG, Galande AK, Shearer AG.

PLoS One. 2013 Dec 30;8(12):e84508. doi: 10.1371/journal.pone.0084508. eCollection 2013.

14.
15.

The metagenomic telescope.

Szalkai B, Scheer I, Nagy K, Vértessy BG, Grolmusz V.

PLoS One. 2014 Jul 23;9(7):e101605. doi: 10.1371/journal.pone.0101605. eCollection 2014.

16.

Enzyme genomics: Application of general enzymatic screens to discover new enzymes.

Kuznetsova E, Proudfoot M, Sanders SA, Reinking J, Savchenko A, Arrowsmith CH, Edwards AM, Yakunin AF.

FEMS Microbiol Rev. 2005 Apr;29(2):263-79. Review.

17.

Comparative genomics of nucleotide metabolism: a tour to the past of the three cellular domains of life.

Armenta-Medina D, Segovia L, Perez-Rueda E.

BMC Genomics. 2014 Sep 17;15:800. doi: 10.1186/1471-2164-15-800.

18.

Call for an enzyme genomics initiative.

Karp PD.

Genome Biol. 2004;5(8):401. Epub 2004 Jul 30.

19.

High precision multi-genome scale reannotation of enzyme function by EFICAz.

Arakaki AK, Tian W, Skolnick J.

BMC Genomics. 2006 Dec 13;7:315.

20.

Protein structure prediction and analysis as a tool for functional genomics.

Baker EN, Arcus VL, Lott JS.

Appl Bioinformatics. 2003;2(3 Suppl):S3-10.

PMID:
15130810

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