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Items: 1 to 20 of 89

1.

Manipulation of endogenous kinase activity in living cells using photoswitchable inhibitory peptides.

Yi JJ, Wang H, Vilela M, Danuser G, Hahn KM.

ACS Synth Biol. 2014 Nov 21;3(11):788-95. doi: 10.1021/sb5001356. Epub 2014 Jun 13.

2.

Designing photoswitchable peptides using the AsLOV2 domain.

Lungu OI, Hallett RA, Choi EJ, Aiken MJ, Hahn KM, Kuhlman B.

Chem Biol. 2012 Apr 20;19(4):507-17. doi: 10.1016/j.chembiol.2012.02.006. Erratum in: Chem Biol. 2012 Jul 27;19(7):926.

3.

Signaling mechanisms of LOV domains: new insights from molecular dynamics studies.

Freddolino PL, Gardner KH, Schulten K.

Photochem Photobiol Sci. 2013 Jul;12(7):1158-70. doi: 10.1039/c3pp25400c.

4.

Optical Control of Peroxisomal Trafficking.

Spiltoir JI, Strickland D, Glotzer M, Tucker CL.

ACS Synth Biol. 2016 Jul 15;5(7):554-60. doi: 10.1021/acssynbio.5b00144. Epub 2015 Nov 2.

5.

Spatiotemporal control of small GTPases with light using the LOV domain.

Wu YI, Wang X, He L, Montell D, Hahn KM.

Methods Enzymol. 2011;497:393-407. doi: 10.1016/B978-0-12-385075-1.00016-0.

6.

Optogenetics: optical control of a photoactivatable Rac in living cells.

Yin T, Wu YI.

Methods Mol Biol. 2015;1251:277-89. doi: 10.1007/978-1-4939-2080-8_15.

PMID:
25391805
7.

Blue light induces global and localized conformational changes in the kinase domain of full-length phototropin.

Pfeifer A, Mathes T, Lu Y, Hegemann P, Kottke T.

Biochemistry. 2010 Feb 9;49(5):1024-32. doi: 10.1021/bi9016044.

PMID:
20052995
8.

The amino-terminal helix modulates light-activated conformational changes in AsLOV2.

Zayner JP, Antoniou C, Sosnick TR.

J Mol Biol. 2012 May 25;419(1-2):61-74. doi: 10.1016/j.jmb.2012.02.037. Epub 2012 Mar 7.

9.

Engineering and Application of LOV2-Based Photoswitches.

Zimmerman SP, Kuhlman B, Yumerefendi H.

Methods Enzymol. 2016;580:169-90. doi: 10.1016/bs.mie.2016.05.058. Epub 2016 Jul 1.

10.

Blue-light-induced unfolding of the Jα helix allows for the dimerization of aureochrome-LOV from the diatom Phaeodactylum tricornutum.

Herman E, Sachse M, Kroth PG, Kottke T.

Biochemistry. 2013 May 7;52(18):3094-101. doi: 10.1021/bi400197u. Epub 2013 Apr 26.

PMID:
23621750
11.

Molecular mechanism of phototropin light signaling.

Okajima K.

J Plant Res. 2016 Mar;129(2):149-57. doi: 10.1007/s10265-016-0783-6. Epub 2016 Jan 27. Review.

PMID:
26815763
12.

Different role of the Jalpha helix in the light-induced activation of the LOV2 domains in various phototropins.

Koyama T, Iwata T, Yamamoto A, Sato Y, Matsuoka D, Tokutomi S, Kandori H.

Biochemistry. 2009 Aug 18;48(32):7621-8. doi: 10.1021/bi9009192.

PMID:
19601589
13.

Dynamics of light-induced activation in the PAS domain proteins LOV2 and PYP probed by time-resolved tryptophan fluorescence.

Hoersch D, Bolourchian F, Otto H, Heyn MP, Bogomolni RA.

Biochemistry. 2010 Dec 28;49(51):10811-7. doi: 10.1021/bi101413v. Epub 2010 Dec 2.

PMID:
21090690
14.

A strategy to identify stable membrane-permeant peptide inhibitors of myosin light chain kinase.

Owens SE, Graham WV, Siccardi D, Turner JR, Mrsny RJ.

Pharm Res. 2005 May;22(5):703-9. Epub 2005 May 17.

PMID:
15906163
15.

Rationally improving LOV domain-based photoswitches.

Strickland D, Yao X, Gawlak G, Rosen MK, Gardner KH, Sosnick TR.

Nat Methods. 2010 Aug;7(8):623-6. doi: 10.1038/nmeth.1473. Epub 2010 Jun 20.

16.

Biophysical, mutational, and functional investigation of the chromophore-binding pocket of light-oxygen-voltage photoreceptors.

Diensthuber RP, Engelhard C, Lemke N, Gleichmann T, Ohlendorf R, Bittl R, Möglich A.

ACS Synth Biol. 2014 Nov 21;3(11):811-9. doi: 10.1021/sb400205x. Epub 2014 Mar 5.

PMID:
24926890
17.

Disruption of the LOV-Jalpha helix interaction activates phototropin kinase activity.

Harper SM, Christie JM, Gardner KH.

Biochemistry. 2004 Dec 28;43(51):16184-92.

PMID:
15610012
18.

Controlling the DNA cleavage activity of light-inducible chimeric endonucleases by bidirectional photoactivation.

Schierling B, Pingoud A.

Bioconjug Chem. 2012 Jun 20;23(6):1105-9. doi: 10.1021/bc3001326. Epub 2012 May 11.

PMID:
22559722
19.

Inhibition of CREB phosphorylation by conjugates of adenosine analogues and arginine-rich peptides, inhibitors of PKA catalytic subunit.

Kriisa M, Sinijärv H, Vaasa A, Enkvist E, Kostenko S, Moens U, Uri A.

Chembiochem. 2015 Jan 19;16(2):312-9. doi: 10.1002/cbic.201402526. Epub 2014 Dec 8.

PMID:
25487811
20.

Mutations in N-terminal flanking region of blue light-sensing light-oxygen and voltage 2 (LOV2) domain disrupt its repressive activity on kinase domain in the Chlamydomonas phototropin.

Aihara Y, Yamamoto T, Okajima K, Yamamoto K, Suzuki T, Tokutomi S, Tanaka K, Nagatani A.

J Biol Chem. 2012 Mar 23;287(13):9901-9. doi: 10.1074/jbc.M111.324723. Epub 2012 Jan 30.

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