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Insights into the structure and architecture of the CCR4-NOT complex.

Xu K, Bai Y, Zhang A, Zhang Q, Bartlam MG.

Front Genet. 2014 May 16;5:137. doi: 10.3389/fgene.2014.00137. eCollection 2014. Review.


The Ccr4-Not Complex: Architecture and Structural Insights.

Collart MA, Panasenko OO.

Subcell Biochem. 2017;83:349-379. doi: 10.1007/978-3-319-46503-6_13.


The structural basis for deadenylation by the CCR4-NOT complex.

Bartlam M, Yamamoto T.

Protein Cell. 2010 May;1(5):443-52. doi: 10.1007/s13238-010-0060-8. Epub 2010 Jun 4. Review.


NOT10 and C2orf29/NOT11 form a conserved module of the CCR4-NOT complex that docks onto the NOT1 N-terminal domain.

Bawankar P, Loh B, Wohlbold L, Schmidt S, Izaurralde E.

RNA Biol. 2013 Feb;10(2):228-44. doi: 10.4161/rna.23018. Epub 2013 Jan 9.


Architecture of the nuclease module of the yeast Ccr4-not complex: the Not1-Caf1-Ccr4 interaction.

Basquin J, Roudko VV, Rode M, Basquin C, Séraphin B, Conti E.

Mol Cell. 2012 Oct 26;48(2):207-18. doi: 10.1016/j.molcel.2012.08.014. Epub 2012 Sep 6.


The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex.

Petit AP, Wohlbold L, Bawankar P, Huntzinger E, Schmidt S, Izaurralde E, Weichenrieder O.

Nucleic Acids Res. 2012 Nov;40(21):11058-72. doi: 10.1093/nar/gks883. Epub 2012 Sep 12.


The enzyme activities of Caf1 and Ccr4 are both required for deadenylation by the human Ccr4-Not nuclease module.

Maryati M, Airhihen B, Winkler GS.

Biochem J. 2015 Jul 1;469(1):169-76. doi: 10.1042/BJ20150304. Epub 2015 May 6.


The role of the CNOT1 subunit of the CCR4-NOT complex in mRNA deadenylation and cell viability.

Ito K, Takahashi A, Morita M, Suzuki T, Yamamoto T.

Protein Cell. 2011 Sep;2(9):755-63. doi: 10.1007/s13238-011-1092-4. Epub 2011 Oct 6.


Heterogeneity and complexity within the nuclease module of the Ccr4-Not complex.

Winkler GS, Balacco DL.

Front Genet. 2013 Dec 23;4:296. doi: 10.3389/fgene.2013.00296. Review.


The Not4 E3 ligase and CCR4 deadenylase play distinct roles in protein quality control.

Halter D, Collart MA, Panasenko OO.

PLoS One. 2014 Jan 17;9(1):e86218. doi: 10.1371/journal.pone.0086218. eCollection 2014.


Roles of mRNA fate modulators Dhh1 and Pat1 in TNRC6-dependent gene silencing recapitulated in yeast.

Makino S, Mishima Y, Inoue K, Inada T.

J Biol Chem. 2015 Mar 27;290(13):8331-47. doi: 10.1074/jbc.M114.615088. Epub 2015 Feb 5.


C2ORF29/CNOT11 and CNOT10 form a new module of the CCR4-NOT complex.

Mauxion F, Prève B, Séraphin B.

RNA Biol. 2013 Feb;10(2):267-76. doi: 10.4161/rna.23065. Epub 2012 Dec 11.


Subunits of the Drosophila CCR4-NOT complex and their roles in mRNA deadenylation.

Temme C, Zhang L, Kremmer E, Ihling C, Chartier A, Sinz A, Simonelig M, Wahle E.

RNA. 2010 Jul;16(7):1356-70. doi: 10.1261/rna.2145110. Epub 2010 May 26.


Structural basis for the recruitment of the human CCR4-NOT deadenylase complex by tristetraprolin.

Fabian MR, Frank F, Rouya C, Siddiqui N, Lai WS, Karetnikov A, Blackshear PJ, Nagar B, Sonenberg N.

Nat Struct Mol Biol. 2013 Jun;20(6):735-9. doi: 10.1038/nsmb.2572. Epub 2013 May 5.


Not1 mediates recruitment of the deadenylase Caf1 to mRNAs targeted for degradation by tristetraprolin.

Sandler H, Kreth J, Timmers HT, Stoecklin G.

Nucleic Acids Res. 2011 May;39(10):4373-86. doi: 10.1093/nar/gkr011. Epub 2011 Jan 29.


Structure and assembly of the NOT module of the human CCR4-NOT complex.

Boland A, Chen Y, Raisch T, Jonas S, Kuzuoğlu-Öztürk D, Wohlbold L, Weichenrieder O, Izaurralde E.

Nat Struct Mol Biol. 2013 Nov;20(11):1289-97. doi: 10.1038/nsmb.2681. Epub 2013 Oct 13.


PUF3 acceleration of deadenylation in vivo can operate independently of CCR4 activity, possibly involving effects on the PAB1-mRNP structure.

Lee D, Ohn T, Chiang YC, Quigley G, Yao G, Liu Y, Denis CL.

J Mol Biol. 2010 Jun 18;399(4):562-75. doi: 10.1016/j.jmb.2010.04.034. Epub 2010 May 8.


The CCR4-NOT complex plays diverse roles in mRNA metabolism.

Denis CL, Chen J.

Prog Nucleic Acid Res Mol Biol. 2003;73:221-50. Review.


CCR4-NOT deadenylates mRNA associated with RNA-induced silencing complexes in human cells.

Piao X, Zhang X, Wu L, Belasco JG.

Mol Cell Biol. 2010 Mar;30(6):1486-94. doi: 10.1128/MCB.01481-09. Epub 2010 Jan 11.


Novel interaction between CCR4 and CAF1 in rice CCR4-NOT deadenylase complex.

Chou WL, Chung YL, Fang JC, Lu CA.

Plant Mol Biol. 2017 Jan;93(1-2):79-96. doi: 10.1007/s11103-016-0548-6. Epub 2016 Oct 6.


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