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Items: 1 to 20 of 96

1.
2.

Natural combinatorial biosynthesis involving two clusters for the synthesis of three pyrrolamides in Streptomyces netropsis.

Vingadassalon A, Lorieux F, Juguet M, Le Goff G, Gerbaud C, Pernodet JL, Lautru S.

ACS Chem Biol. 2015 Feb 20;10(2):601-10. doi: 10.1021/cb500652n.

PMID:
25415678
3.

A sweet origin for the key congocidine precursor 4-acetamidopyrrole-2-carboxylate.

Lautru S, Song L, Demange L, Lombès T, Galons H, Challis GL, Pernodet JL.

Angew Chem Int Ed Engl. 2012 Jul 23;51(30):7454-8. doi: 10.1002/anie.201201445. No abstract available.

PMID:
22707277
4.

Mutasynthesis of pyrrole spiroketal compound using calcimycin 3-hydroxy anthranilic acid biosynthetic mutant.

Gou L, Wu Q, Lin S, Li X, Liang J, Zhou X, An D, Deng Z, Wang Z.

Appl Microbiol Biotechnol. 2013 Sep;97(18):8183-91. doi: 10.1007/s00253-013-4882-1.

PMID:
23666477
5.

An iterative nonribosomal peptide synthetase assembles the pyrrole-amide antibiotic congocidine in Streptomyces ambofaciens.

Juguet M, Lautru S, Francou FX, Nezbedová S, Leblond P, Gondry M, Pernodet JL.

Chem Biol. 2009 Apr 24;16(4):421-31. doi: 10.1016/j.chembiol.2009.03.010.

6.

Enzymatic Evidence for a Revised Congocidine Biosynthetic Pathway.

Al-Mestarihi AH, Garzan A, Kim JM, Garneau-Tsodikova S.

Chembiochem. 2015 Jun 15;16(9):1307-13. doi: 10.1002/cbic.201402711.

PMID:
25958990
7.

Genome mining of Streptomyces ambofaciens.

Aigle B, Lautru S, Spiteller D, Dickschat JS, Challis GL, Leblond P, Pernodet JL.

J Ind Microbiol Biotechnol. 2014 Feb;41(2):251-63. doi: 10.1007/s10295-013-1379-y. Review.

PMID:
24258629
8.

Pyrrolamide DNA gyrase inhibitors: fragment-based nuclear magnetic resonance screening to identify antibacterial agents.

Eakin AE, Green O, Hales N, Walkup GK, Bist S, Singh A, Mullen G, Bryant J, Embrey K, Gao N, Breeze A, Timms D, Andrews B, Uria-Nickelsen M, Demeritt J, Loch JT 3rd, Hull K, Blodgett A, Illingworth RN, Prince B, Boriack-Sjodin PA, Hauck S, MacPherson LJ, Ni H, Sherer B.

Antimicrob Agents Chemother. 2012 Mar;56(3):1240-6. doi: 10.1128/AAC.05485-11.

9.

New aminocoumarins from the rare actinomycete Catenulispora acidiphila DSM 44928: identification, structure elucidation, and heterologous production.

Zettler J, Xia H, Burkard N, Kulik A, Grond S, Heide L, Apel AK.

Chembiochem. 2014 Mar 3;15(4):612-21. doi: 10.1002/cbic.201300712.

PMID:
24554531
10.

Use of a phosphonate methyltransferase in the identification of the fosfazinomycin biosynthetic gene cluster.

Gao J, Ju KS, Yu X, Velásquez JE, Mukherjee S, Lee J, Zhao C, Evans BS, Doroghazi JR, Metcalf WW, van der Donk WA.

Angew Chem Int Ed Engl. 2014 Jan 27;53(5):1334-7. doi: 10.1002/anie.201308363.

11.
12.

Characterization of the Biosynthetic Gene Cluster for Benzoxazole Antibiotics A33853 Reveals Unusual Assembly Logic.

Lv M, Zhao J, Deng Z, Yu Y.

Chem Biol. 2015 Oct 22;22(10):1313-24. doi: 10.1016/j.chembiol.2015.09.005.

13.

Two pathways for pyrrole formation in coumermycin A(1) biosynthesis: the central pyrrole moiety is formed from L-threonine.

Siebenberg S, Burkard N, Knuplesch A, Gust B, Grond S, Heide L.

Chembiochem. 2011 Nov 25;12(17):2677-85. doi: 10.1002/cbic.201100494.

PMID:
21953874
14.

Novel natural products from soil DNA libraries in a streptomycete host.

Wang GY, Graziani E, Waters B, Pan W, Li X, McDermott J, Meurer G, Saxena G, Andersen RJ, Davies J.

Org Lett. 2000 Aug 10;2(16):2401-4.

PMID:
10956506
15.

The regulation of the secondary metabolism of Streptomyces: new links and experimental advances.

van Wezel GP, McDowall KJ.

Nat Prod Rep. 2011 Jul;28(7):1311-33. doi: 10.1039/c1np00003a. Review.

PMID:
21611665
16.

Prodigiosin biosynthesis gene cluster in the roseophilin producer Streptomyces griseoviridis.

Kawasaki T, Sakurai F, Nagatsuka SY, Hayakawa Y.

J Antibiot (Tokyo). 2009 May;62(5):271-6. doi: 10.1038/ja.2009.27.

PMID:
19329986
17.

Pyrrolamide DNA gyrase inhibitors: optimization of antibacterial activity and efficacy.

Sherer BA, Hull K, Green O, Basarab G, Hauck S, Hill P, Loch JT 3rd, Mullen G, Bist S, Bryant J, Boriack-Sjodin A, Read J, DeGrace N, Uria-Nickelsen M, Illingworth RN, Eakin AE.

Bioorg Med Chem Lett. 2011 Dec 15;21(24):7416-20. doi: 10.1016/j.bmcl.2011.10.010.

PMID:
22041057
18.

Biosynthesis of the terpene phenalinolactone in Streptomyces sp. Tü6071: analysis of the gene cluster and generation of derivatives.

Dürr C, Schnell HJ, Luzhetskyy A, Murillo R, Weber M, Welzel K, Vente A, Bechthold A.

Chem Biol. 2006 Apr;13(4):365-77.

19.

Genome mining-directed activation of a silent angucycline biosynthetic gene cluster in Streptomyces chattanoogensis.

Zhou Z, Xu Q, Bu Q, Guo Y, Liu S, Liu Y, Du Y, Li Y.

Chembiochem. 2015 Feb 9;16(3):496-502. doi: 10.1002/cbic.201402577.

PMID:
25511454
20.

Cloning, heterologous expression, and characterization of the gene cluster required for gougerotin biosynthesis.

Niu G, Li L, Wei J, Tan H.

Chem Biol. 2013 Jan 24;20(1):34-44. doi: 10.1016/j.chembiol.2012.10.017.

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