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Items: 1 to 20 of 128

1.

Specific potassium ion interactions facilitate homocysteine binding to betaine-homocysteine S-methyltransferase.

Mládková J, Hladílková J, Diamond CE, Tryon K, Yamada K, Garrow TA, Jungwirth P, Koutmos M, Jiráček J.

Proteins. 2014 Oct;82(10):2552-64. doi: 10.1002/prot.24619. Epub 2014 Jun 17.

PMID:
24895213
2.

Betaine-homocysteine S-methyltransferase-2 is an S-methylmethionine-homocysteine methyltransferase.

Szegedi SS, Castro CC, Koutmos M, Garrow TA.

J Biol Chem. 2008 Apr 4;283(14):8939-45. doi: 10.1074/jbc.M710449200. Epub 2008 Jan 29.

3.

Dissecting the catalytic mechanism of betaine-homocysteine S-methyltransferase by use of intrinsic tryptophan fluorescence and site-directed mutagenesis.

Castro C, Gratson AA, Evans JC, Jiracek J, Collinsová M, Ludwig ML, Garrow TA.

Biochemistry. 2004 May 11;43(18):5341-51.

PMID:
15122900
4.
6.

Double-headed sulfur-linked amino acids as first inhibitors for betaine-homocysteine S-methyltransferase 2.

Mládková J, Vaněk V, Buděšínský M, Elbert T, Demianová Z, Garrow TA, Jiráček J.

J Med Chem. 2012 Aug 9;55(15):6822-31. doi: 10.1021/jm300571h. Epub 2012 Jul 18. Erratum in: J Med Chem. 2012 Oct 25;55(20):8974.

PMID:
22775318
7.

Betaine homocysteine S-methyltransferase: just a regulator of homocysteine metabolism?

Pajares MA, Pérez-Sala D.

Cell Mol Life Sci. 2006 Dec;63(23):2792-803. Review.

PMID:
17086380
8.

Crystal structure of rat liver betaine homocysteine s-methyltransferase reveals new oligomerization features and conformational changes upon substrate binding.

González B, Pajares MA, Martínez-Ripoll M, Blundell TL, Sanz-Aparicio J.

J Mol Biol. 2004 May 7;338(4):771-82.

PMID:
15099744
9.

Betaine-homocysteine methyltransferase: zinc in a distorted barrel.

Evans JC, Huddler DP, Jiracek J, Castro C, Millian NS, Garrow TA, Ludwig ML.

Structure. 2002 Sep;10(9):1159-71.

10.

Splicing variants of the porcine betaine-homocysteine S-methyltransferase gene: implications for mammalian metabolism.

Ganu R, Garrow T, Koutmos M, Rund L, Schook LB.

Gene. 2013 Oct 25;529(2):228-37. doi: 10.1016/j.gene.2013.07.103. Epub 2013 Aug 13.

11.
12.

Betaine homocysteine methyltransferase is active in the mouse blastocyst and promotes inner cell mass development.

Lee MB, Kooistra M, Zhang B, Slow S, Fortier AL, Garrow TA, Lever M, Trasler JM, Baltz JM.

J Biol Chem. 2012 Sep 21;287(39):33094-103. Epub 2012 Jul 30.

13.
14.

The development of a new class of inhibitors for betaine-homocysteine S-methyltransferase.

Pícha J, Vaněk V, Buděšínský M, Mládková J, Garrow TA, Jiráček J.

Eur J Med Chem. 2013 Jul;65:256-75. doi: 10.1016/j.ejmech.2013.04.039. Epub 2013 Apr 30.

PMID:
23727536
15.

Effects of diabetes and insulin on betaine-homocysteine S-methyltransferase expression in rat liver.

Ratnam S, Wijekoon EP, Hall B, Garrow TA, Brosnan ME, Brosnan JT.

Am J Physiol Endocrinol Metab. 2006 May;290(5):E933-9. Epub 2005 Dec 13.

16.

Crystallization and preliminary X-ray crystallographic studies of recombinant human betaine-homocysteine S-methyltransferase.

Bose N, Momany C.

Acta Crystallogr D Biol Crystallogr. 2001 Mar;57(Pt 3):431-3.

PMID:
11223523
17.

Alleviation of hepatic fat accumulation by betaine involves reduction of homocysteine via up-regulation of betaine-homocysteine methyltransferase (BHMT).

Ahn CW, Jun DS, Na JD, Choi YJ, Kim YC.

Biochem Biophys Res Commun. 2016 Aug 26;477(3):440-7. doi: 10.1016/j.bbrc.2016.06.080. Epub 2016 Jun 16.

PMID:
27320863
18.

Inhibition of human betaine-homocysteine methyltransferase expression by S-adenosylmethionine and methylthioadenosine.

Ou X, Yang H, Ramani K, Ara AI, Chen H, Mato JM, Lu SC.

Biochem J. 2007 Jan 1;401(1):87-96.

19.

Interrelations between glycine betaine catabolism and methionine biosynthesis in Sinorhizobium meliloti strain 102F34.

Barra L, Fontenelle C, Ermel G, Trautwetter A, Walker GC, Blanco C.

J Bacteriol. 2006 Oct;188(20):7195-204.

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