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Mutation and expression analysis of the IDH1, IDH2, DNMT3A, and MYD88 genes in colorectal cancer.

Li WL, Xiao MS, Zhang DF, Yu D, Yang RX, Li XY, Yao YG.

Gene. 2014 Aug 10;546(2):263-70. doi: 10.1016/j.gene.2014.05.070. Epub 2014 Jun 2.


IDH1 and IDH2 mutations are frequent in Chinese patients with acute myeloid leukemia but rare in other types of hematological disorders.

Zou Y, Zeng Y, Zhang DF, Zou SH, Cheng YF, Yao YG.

Biochem Biophys Res Commun. 2010 Nov 12;402(2):378-83. doi: 10.1016/j.bbrc.2010.10.038. Epub 2010 Oct 12.


IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study.

Marcucci G, Maharry K, Wu YZ, Radmacher MD, Mrózek K, Margeson D, Holland KB, Whitman SP, Becker H, Schwind S, Metzeler KH, Powell BL, Carter TH, Kolitz JE, Wetzler M, Carroll AJ, Baer MR, Caligiuri MA, Larson RA, Bloomfield CD.

J Clin Oncol. 2010 May 10;28(14):2348-55. doi: 10.1200/JCO.2009.27.3730. Epub 2010 Apr 5.


Comparative examination of various PCR-based methods for DNMT3A and IDH1/2 mutations identification in acute myeloid leukemia.

Berenstein R, Blau IW, Kar A, Cay R, Sindram A, Seide C, Blau O.

J Exp Clin Cancer Res. 2014 May 21;33:44. doi: 10.1186/1756-9966-33-44.


Cooperating gene mutations in childhood acute myeloid leukemia with special reference on mutations of ASXL1, TET2, IDH1, IDH2, and DNMT3A.

Liang DC, Liu HC, Yang CP, Jaing TH, Hung IJ, Yeh TC, Chen SH, Hou JY, Huang YJ, Shih YS, Huang YH, Lin TH, Shih LY.

Blood. 2013 Apr 11;121(15):2988-95. doi: 10.1182/blood-2012-06-436782. Epub 2013 Jan 30.


Leukemic mutations in the methylation-associated genes DNMT3A and IDH2 are rare events in pediatric AML: a report from the Children's Oncology Group.

Ho PA, Kutny MA, Alonzo TA, Gerbing RB, Joaquin J, Raimondi SC, Gamis AS, Meshinchi S.

Pediatr Blood Cancer. 2011 Aug;57(2):204-9. doi: 10.1002/pbc.23179. Epub 2011 Apr 18.


IDH1 and IDH2 mutation analysis in Chinese patients with acute myeloid leukemia and myelodysplastic syndrome.

Lin J, Yao DM, Qian J, Chen Q, Qian W, Li Y, Yang J, Wang CZ, Chai HY, Qian Z, Xiao GF, Xu WR.

Ann Hematol. 2012 Apr;91(4):519-25. doi: 10.1007/s00277-011-1352-7. Epub 2011 Oct 14.


MicroRNA-143 targets DNA methyltransferases 3A in colorectal cancer.

Ng EK, Tsang WP, Ng SS, Jin HC, Yu J, Li JJ, Röcken C, Ebert MP, Kwok TT, Sung JJ.

Br J Cancer. 2009 Aug 18;101(4):699-706. doi: 10.1038/sj.bjc.6605195. Epub 2009 Jul 28.


Mathematical analysis predicts imbalanced IDH1/2 expression associates with 2-HG-inactivating β-oxygenation pathway in colorectal cancer.

Koseki J, Colvin H, Fukusumi T, Nishida N, Konno M, Kawamoto K, Tsunekuni K, Matsui H, Doki Y, Mori M, Ishii H.

Int J Oncol. 2015 Mar;46(3):1181-91. doi: 10.3892/ijo.2015.2833. Epub 2015 Jan 12.


Analysis of IDH1 and IDH2 mutations in Japanese glioma patients.

Sonoda Y, Kumabe T, Nakamura T, Saito R, Kanamori M, Yamashita Y, Suzuki H, Tominaga T.

Cancer Sci. 2009 Oct;100(10):1996-8. doi: 10.1111/j.1349-7006.2009.01270.x.


IDH1 p.R132 mutations may not be actively involved in the carcinogenesis of hepatocellular carcinoma.

Lu J, Xu L, Zou Y, Yang RX, Fan Y, Zhang W, Yu D, Yao YG.

Med Sci Monit. 2014 Feb 14;20:247-54. doi: 10.12659/MSM.889891.


[Analysis of IDH1 and IDH2 mutations in patients with acute myeloid leukemia].

Jia ZX, Zhou M, Chao HY, Lu XZ, Zhang R, Cen L, Xiao R, Jiang NK.

Zhonghua Xue Ye Xue Za Zhi. 2012 May;33(5):397-401. Chinese.


Comparison of high-resolution melting analysis with direct sequencing for the detection of recurrent mutations in DNA methyltransferase 3A and isocitrate dehydrogenase 1 and 2 genes in acute myeloid leukemia patients.

Gorniak P, Ejduk A, Borg K, Makuch-Lasica H, Nowak G, Lech-Maranda E, Prochorec-Sobieszek M, Warzocha K, Juszczynski P.

Eur J Haematol. 2016 Feb;96(2):181-7. doi: 10.1111/ejh.12566. Epub 2015 May 13.


All the 1p19q codeleted gliomas are mutated on IDH1 or IDH2.

Labussière M, Idbaih A, Wang XW, Marie Y, Boisselier B, Falet C, Paris S, Laffaire J, Carpentier C, Crinière E, Ducray F, El Hallani S, Mokhtari K, Hoang-Xuan K, Delattre JY, Sanson M.

Neurology. 2010 Jun 8;74(23):1886-90. doi: 10.1212/WNL.0b013e3181e1cf3a. Epub 2010 Apr 28.


Genetic polymorphisms of the CASP8 gene promoter may not be associated with colorectal cancer in Han Chinese from southwest China.

Xiao MS, Chang L, Li WL, Du YS, Pan Y, Zhang DF, Wen Y, Luo J, Li XY, Yao YG.

PLoS One. 2013 Jul 2;8(7):e67577. doi: 10.1371/journal.pone.0067577. Print 2013.


Frequent mutation of isocitrate dehydrogenase (IDH)1 and IDH2 in cholangiocarcinoma identified through broad-based tumor genotyping.

Borger DR, Tanabe KK, Fan KC, Lopez HU, Fantin VR, Straley KS, Schenkein DP, Hezel AF, Ancukiewicz M, Liebman HM, Kwak EL, Clark JW, Ryan DP, Deshpande V, Dias-Santagata D, Ellisen LW, Zhu AX, Iafrate AJ.

Oncologist. 2012;17(1):72-9. doi: 10.1634/theoncologist.2011-0386. Epub 2011 Dec 16.


Prognostic significance of DNA methyltransferase 3A mutations in cytogenetically normal acute myeloid leukemia: a study by the Acute Leukemia French Association.

Renneville A, Boissel N, Nibourel O, Berthon C, Helevaut N, Gardin C, Cayuela JM, Hayette S, Reman O, Contentin N, Bordessoule D, Pautas C, Botton Sd, Revel Td, Terre C, Fenaux P, Thomas X, Castaigne S, Dombret H, Preudhomme C.

Leukemia. 2012 Jun;26(6):1247-54. doi: 10.1038/leu.2011.382. Epub 2012 Jan 13.


IDH1 and IDH2 mutations are prognostic but not predictive for outcome in anaplastic oligodendroglial tumors: a report of the European Organization for Research and Treatment of Cancer Brain Tumor Group.

van den Bent MJ, Dubbink HJ, Marie Y, Brandes AA, Taphoorn MJ, Wesseling P, Frenay M, Tijssen CC, Lacombe D, Idbaih A, van Marion R, Kros JM, Dinjens WN, Gorlia T, Sanson M.

Clin Cancer Res. 2010 Mar 1;16(5):1597-604. doi: 10.1158/1078-0432.CCR-09-2902. Epub 2010 Feb 16.


Absence of DICER1, CTCF, RPL22, DNMT3A, TRRAP, IDH1 and IDH2 hotspot mutations in patients with various subtypes of ovarian carcinomas.

Zou Y, Huang MZ, Liu FY, Yang BC, Wang LQ, Wang F, Yu XH, Wan L, Wan XD, Xu XY, Li W, Huang OP, He M.

Biomed Rep. 2015 Jan;3(1):33-37. Epub 2014 Nov 7.


IDH1 and IDH2 mutations are frequent genetic alterations in acute myeloid leukemia and confer adverse prognosis in cytogenetically normal acute myeloid leukemia with NPM1 mutation without FLT3 internal tandem duplication.

Paschka P, Schlenk RF, Gaidzik VI, Habdank M, Krönke J, Bullinger L, Späth D, Kayser S, Zucknick M, Götze K, Horst HA, Germing U, Döhner H, Döhner K.

J Clin Oncol. 2010 Aug 1;28(22):3636-43. doi: 10.1200/JCO.2010.28.3762. Epub 2010 Jun 21.


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