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Synthetic surfactant containing SP-B and SP-C mimics is superior to single-peptide formulations in rabbits with chemical acute lung injury.

Walther FJ, Hernández-Juviel JM, Gordon LM, Waring AJ.

PeerJ. 2014 May 22;2:e393. doi: 10.7717/peerj.393. eCollection 2014.


Synthetic lung surfactants containing SP-B and SP-C peptides plus novel phospholipase-resistant lipids or glycerophospholipids.

Notter RH, Gupta R, Schwan AL, Wang Z, Shkoor MG, Walther FJ.

PeerJ. 2016 Oct 27;4:e2635. eCollection 2016.


Activity and biophysical inhibition resistance of a novel synthetic lung surfactant containing Super-Mini-B DATK peptide.

Notter RH, Wang Z, Walther FJ.

PeerJ. 2016 Jan 5;4:e1528. doi: 10.7717/peerj.1528. eCollection 2016.


Aerosol delivery of synthetic lung surfactant.

Walther FJ, Hernández-Juviel JM, Waring AJ.

PeerJ. 2014 May 27;2:e403. doi: 10.7717/peerj.403. eCollection 2014.


Synthetic lung surfactant reduces alveolar-capillary protein leakage in surfactant-deficient rabbits.

Gupta R, Hernández-Juviel JM, Waring AJ, Walther FJ.

Exp Lung Res. 2015 Jun;41(5):293-9. doi: 10.3109/01902148.2015.1024354.


Synthetic surfactant based on analogues of SP-B and SP-C is superior to single-peptide surfactants in ventilated premature rabbits.

Almlén A, Walther FJ, Waring AJ, Robertson B, Johansson J, Curstedt T.

Neonatology. 2010 Jun;98(1):91-9. doi: 10.1159/000276980. Epub 2010 Jan 21.


Sensitivity of synthetic surfactants to albumin inhibition in preterm rabbits.

Mbagwu N, Bruni R, Hernández-Juviel JM, Waring AJ, Walther FJ.

Mol Genet Metab. 1999 Jan;66(1):40-8.


A sulfur-free peptide mimic of surfactant protein B (B-YL) exhibits high in vitro and in vivo surface activities.

Walther FJ, Gupta M, Gordon LM, Waring AJ.

Version 2. Gates Open Res. 2018 Jul 10 [revised 2018 Jan 1];2:13. doi: 10.12688/gatesopenres.12799.2. eCollection 2018.


Surfactant lavage with lidocaine improves pulmonary function in piglets after HCl-induced acute lung injury.

Huang TK, Uyehara CF, Balaraman V, Miyasato CY, Person D, Egan E, Easa D.

Lung. 2004;182(1):15-25.


Changes in respiratory elastance after deep inspirations reflect surface film functionality in mice with acute lung injury.

Takahashi A, Bartolák-Suki E, Majumdar A, Suki B.

J Appl Physiol (1985). 2015 Aug 1;119(3):258-65. doi: 10.1152/japplphysiol.00476.2014. Epub 2015 Jun 11.


A synthetic surfactant based on a poly-Leu SP-C analog and phospholipids: effects on tidal volumes and lung gas volumes in ventilated immature newborn rabbits.

Johansson J, Some M, Linderholm BM, Almlén A, Curstedt T, Robertson B.

J Appl Physiol (1985). 2003 Nov;95(5):2055-63. Epub 2003 Aug 1.


Aerosol delivery of dry powder synthetic lung surfactant to surfactant-deficient rabbits and preterm lambs on non-invasive respiratory support.

Walther FJ, Gupta M, Lipp MM, Chan H, Krzewick J, Gordon LM, Waring AJ.

Gates Open Res. 2019 Mar 14;3:6. doi: 10.12688/gatesopenres.12899.2. eCollection 2019.


Surfactant proteins B and C are both necessary for alveolar stability at end expiration in premature rabbits with respiratory distress syndrome.

Almlén A, Stichtenoth G, Linderholm B, Haegerstrand-Björkman M, Robertson B, Johansson J, Curstedt T.

J Appl Physiol (1985). 2008 Apr;104(4):1101-8. doi: 10.1152/japplphysiol.00865.2007. Epub 2008 Feb 14.


Hyaluronan with dextran added to therapeutic lung surfactants improves effectiveness in vitro and in vivo.

Lu KW, Taeusch HW, Clements JA.

Exp Lung Res. 2013 May-Jun;39(4-5):191-200. doi: 10.3109/01902148.2013.791893. Epub 2013 May 3.


Hydrophobic surfactant proteins and their analogues.

Walther FJ, Waring AJ, Sherman MA, Zasadzinski JA, Gordon LM.

Neonatology. 2007;91(4):303-10. Epub 2007 Jun 7. Review.


The effect of a peptide-containing synthetic lung surfactant on gas exchange and lung mechanics in a rabbit model of surfactant depletion.

van Zyl JM, Smith J, Hawtrey A.

Drug Des Devel Ther. 2013;7:139-48. doi: 10.2147/DDDT.S40622. Epub 2013 Mar 11.


Comparison of three lipid formulations for synthetic surfactant with a surfactant protein B analog.

Walther FJ, Hernández-Juviel JM, Gordon LM, Waring AJ, Stenger P, Zasadzinski JA.

Exp Lung Res. 2005 Jul-Aug;31(6):563-79.


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