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Items: 1 to 20 of 146

1.

Identification of erythroferrone as an erythroid regulator of iron metabolism.

Kautz L, Jung G, Valore EV, Rivella S, Nemeth E, Ganz T.

Nat Genet. 2014 Jul;46(7):678-84. doi: 10.1038/ng.2996. Epub 2014 Jun 1.

2.

Erythroferrone contributes to hepcidin suppression and iron overload in a mouse model of β-thalassemia.

Kautz L, Jung G, Du X, Gabayan V, Chapman J, Nasoff M, Nemeth E, Ganz T.

Blood. 2015 Oct 22;126(17):2031-7. doi: 10.1182/blood-2015-07-658419. Epub 2015 Aug 14.

3.

A competitive enzyme-linked immunosorbent assay specific for murine hepcidin-1: correlation with hepatic mRNA expression in established and novel models of dysregulated iron homeostasis.

Gutschow P, Schmidt PJ, Han H, Ostland V, Bartnikas TB, Pettiglio MA, Herrera C, Butler JS, Nemeth E, Ganz T, Fleming MD, Westerman M.

Haematologica. 2015 Feb;100(2):167-77. doi: 10.3324/haematol.2014.116723. Epub 2014 Nov 25.

4.

Erythroferrone contributes to recovery from anemia of inflammation.

Kautz L, Jung G, Nemeth E, Ganz T.

Blood. 2014 Oct 16;124(16):2569-74. doi: 10.1182/blood-2014-06-584607. Epub 2014 Sep 5.

5.

Characterization of Putative Erythroid Regulators of Hepcidin in Mouse Models of Anemia.

Mirciov CS, Wilkins SJ, Dunn LA, Anderson GJ, Frazer DM.

PLoS One. 2017 Jan 30;12(1):e0171054. doi: 10.1371/journal.pone.0171054. eCollection 2017.

6.

[The role of erythroferrone in iron metabolism: From experimental results to pathogenesis].

Vallet N; Club du Globule Rouge et du Fer.

Rev Med Interne. 2018 Mar;39(3):178-184. doi: 10.1016/j.revmed.2017.05.008. Epub 2017 Jun 27. Review. French.

PMID:
28666715
7.

An RNAi therapeutic targeting Tmprss6 decreases iron overload in Hfe(-/-) mice and ameliorates anemia and iron overload in murine β-thalassemia intermedia.

Schmidt PJ, Toudjarska I, Sendamarai AK, Racie T, Milstein S, Bettencourt BR, Hettinger J, Bumcrot D, Fleming MD.

Blood. 2013 Feb 14;121(7):1200-8. doi: 10.1182/blood-2012-09-453977. Epub 2012 Dec 6.

8.

mRNA expression of iron regulatory genes in beta-thalassemia intermedia and beta-thalassemia major mouse models.

Weizer-Stern O, Adamsky K, Amariglio N, Rachmilewitz E, Breda L, Rivella S, Rechavi G.

Am J Hematol. 2006 Jul;81(7):479-83.

9.

EPO-dependent induction of erythroferrone drives hepcidin suppression and systematic iron absorption under phenylhydrazine-induced hemolytic anemia.

Jiang X, Gao M, Chen Y, Liu J, Qi S, Ma J, Zhang Z, Xu Y.

Blood Cells Mol Dis. 2016 May;58:45-51. doi: 10.1016/j.bcmd.2016.02.005. Epub 2016 Feb 19.

PMID:
27067488
10.

Decreasing TfR1 expression reverses anemia and hepcidin suppression in β-thalassemic mice.

Li H, Choesang T, Bao W, Chen H, Feola M, Garcia-Santos D, Li J, Sun S, Follenzi A, Pham P, Liu J, Zhang J, Ponka P, An X, Mohandas N, Fleming RE, Rivella S, Li G, Ginzburg YZ.

Blood. 2017 Mar 16;129(11):1514-1526. doi: 10.1182/blood-2016-09-742387. Epub 2017 Feb 1. Erratum in: Blood. 2017 Dec 21;130(25):2809.

11.

Associations among Erythroferrone and Biomarkers of Erythropoiesis and Iron Metabolism, and Treatment with Long-Term Erythropoiesis-Stimulating Agents in Patients on Hemodialysis.

Honda H, Kobayashi Y, Onuma S, Shibagaki K, Yuza T, Hirao K, Yamamoto T, Tomosugi N, Shibata T.

PLoS One. 2016 Mar 15;11(3):e0151601. doi: 10.1371/journal.pone.0151601. eCollection 2016.

12.

Deletion of TMPRSS6 attenuates the phenotype in a mouse model of β-thalassemia.

Nai A, Pagani A, Mandelli G, Lidonnici MR, Silvestri L, Ferrari G, Camaschella C.

Blood. 2012 May 24;119(21):5021-9. doi: 10.1182/blood-2012-01-401885. Epub 2012 Apr 6.

13.

Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice.

Gardenghi S, Ramos P, Marongiu MF, Melchiori L, Breda L, Guy E, Muirhead K, Rao N, Roy CN, Andrews NC, Nemeth E, Follenzi A, An X, Mohandas N, Ginzburg Y, Rachmilewitz EA, Giardina PJ, Grady RW, Rivella S.

J Clin Invest. 2010 Dec;120(12):4466-77. doi: 10.1172/JCI41717. Epub 2010 Nov 22.

14.

Liver expression of hepcidin and other iron genes in two mouse models of beta-thalassemia.

De Franceschi L, Daraio F, Filippini A, Carturan S, Muchitsch EM, Roetto A, Camaschella C.

Haematologica. 2006 Oct;91(10):1336-42.

15.

Immunoassay for human serum erythroferrone.

Ganz T, Jung G, Naeim A, Ginzburg Y, Pakbaz Z, Walter PB, Kautz L, Nemeth E.

Blood. 2017 Sep 7;130(10):1243-1246. doi: 10.1182/blood-2017-04-777987. Epub 2017 Jul 24.

16.

Hepcidin.

Ganz T.

Rinsho Ketsueki. 2016;57(10):1913-1917.

PMID:
27725588
17.

Limiting hepatic Bmp-Smad signaling by matriptase-2 is required for erythropoietin-mediated hepcidin suppression in mice.

Nai A, Rubio A, Campanella A, Gourbeyre O, Artuso I, Bordini J, Gineste A, Latour C, Besson-Fournier C, Lin HY, Coppin H, Roth MP, Camaschella C, Silvestri L, Meynard D.

Blood. 2016 May 12;127(19):2327-36. doi: 10.1182/blood-2015-11-681494. Epub 2016 Jan 11.

18.

Exogenous iron increases hemoglobin in beta-thalassemic mice.

Ginzburg YZ, Rybicki AC, Suzuka SM, Hall CB, Breuer W, Cabantchik ZI, Bouhassira EE, Fabry ME, Nagel RL.

Exp Hematol. 2009 Feb;37(2):172-83. doi: 10.1016/j.exphem.2008.10.004. Epub 2008 Dec 6.

PMID:
19059700
19.

New insights into iron regulation and erythropoiesis.

Kim A, Nemeth E.

Curr Opin Hematol. 2015 May;22(3):199-205. doi: 10.1097/MOH.0000000000000132. Review.

20.

Erythropoietin's inhibiting impact on hepcidin expression occurs indirectly.

Gammella E, Diaz V, Recalcati S, Buratti P, Samaja M, Dey S, Noguchi CT, Gassmann M, Cairo G.

Am J Physiol Regul Integr Comp Physiol. 2015 Feb 15;308(4):R330-5. doi: 10.1152/ajpregu.00410.2014. Epub 2014 Dec 17.

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