Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 149

1.

Ribosomal protein-Mdm2-p53 pathway coordinates nutrient stress with lipid metabolism by regulating MCD and promoting fatty acid oxidation.

Liu Y, He Y, Jin A, Tikunov AP, Zhou L, Tollini LA, Leslie P, Kim TH, Li LO, Coleman RA, Gu Z, Chen YQ, Macdonald JM, Graves LM, Zhang Y.

Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):E2414-22. doi: 10.1073/pnas.1315605111. Epub 2014 May 28.

2.

The in vivo role of the RP-Mdm2-p53 pathway in signaling oncogenic stress induced by pRb inactivation and Ras overexpression.

Pan W, Issaq S, Zhang Y.

PLoS One. 2011;6(6):e21625. doi: 10.1371/journal.pone.0021625. Epub 2011 Jun 29.

3.

The RP-Mdm2-p53 pathway and tumorigenesis.

Miliani de Marval PL, Zhang Y.

Oncotarget. 2011 Mar;2(3):234-8. Review.

4.

RPL23 Links Oncogenic RAS Signaling to p53-Mediated Tumor Suppression.

Meng X, Tackmann NR, Liu S, Yang J, Dong J, Wu C, Cox AD, Zhang Y.

Cancer Res. 2016 Sep 1;76(17):5030-9. doi: 10.1158/0008-5472.CAN-15-3420. Epub 2016 Jul 11.

PMID:
27402081
5.

Mice with a Mutation in the Mdm2 Gene That Interferes with MDM2/Ribosomal Protein Binding Develop a Defect in Erythropoiesis.

Kamio T, Gu BW, Olson TS, Zhang Y, Mason PJ, Bessler M.

PLoS One. 2016 Apr 4;11(4):e0152263. doi: 10.1371/journal.pone.0152263. eCollection 2016.

6.

Oncogenic c-Myc-induced lymphomagenesis is inhibited non-redundantly by the p19Arf-Mdm2-p53 and RP-Mdm2-p53 pathways.

Meng X, Carlson NR, Dong J, Zhang Y.

Oncogene. 2015 Nov 12;34(46):5709-17. doi: 10.1038/onc.2015.39. Epub 2015 Mar 30.

7.

An ARF-independent c-MYC-activated tumor suppression pathway mediated by ribosomal protein-Mdm2 Interaction.

Macias E, Jin A, Deisenroth C, Bhat K, Mao H, Lindström MS, Zhang Y.

Cancer Cell. 2010 Sep 14;18(3):231-43. doi: 10.1016/j.ccr.2010.08.007.

8.

SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase.

Laurent G, German NJ, Saha AK, de Boer VC, Davies M, Koves TR, Dephoure N, Fischer F, Boanca G, Vaitheesvaran B, Lovitch SB, Sharpe AH, Kurland IJ, Steegborn C, Gygi SP, Muoio DM, Ruderman NB, Haigis MC.

Mol Cell. 2013 Jun 6;50(5):686-98. doi: 10.1016/j.molcel.2013.05.012.

9.

Ribosomal protein S27-like is a physiological regulator of p53 that suppresses genomic instability and tumorigenesis.

Xiong X, Zhao Y, Tang F, Wei D, Thomas D, Wang X, Liu Y, Zheng P, Sun Y.

Elife. 2014 Aug 21;3:e02236. doi: 10.7554/eLife.02236.

10.

Characterization of rat liver malonyl-CoA decarboxylase and the study of its role in regulating fatty acid metabolism.

Dyck JR, Berthiaume LG, Thomas PD, Kantor PF, Barr AJ, Barr R, Singh D, Hopkins TA, Voilley N, Prentki M, Lopaschuk GD.

Biochem J. 2000 Sep 1;350 Pt 2:599-608.

11.

Ribosomal proteins RPL37, RPS15 and RPS20 regulate the Mdm2-p53-MdmX network.

Daftuar L, Zhu Y, Jacq X, Prives C.

PLoS One. 2013 Jul 16;8(7):e68667. doi: 10.1371/journal.pone.0068667. Print 2013.

12.

Regulation of the MDM2-P53 pathway and tumor growth by PICT1 via nucleolar RPL11.

Sasaki M, Kawahara K, Nishio M, Mimori K, Kogo R, Hamada K, Itoh B, Wang J, Komatsu Y, Yang YR, Hikasa H, Horie Y, Yamashita T, Kamijo T, Zhang Y, Zhu Y, Prives C, Nakano T, Mak TW, Sasaki T, Maehama T, Mori M, Suzuki A.

Nat Med. 2011 Jul 31;17(8):944-51. doi: 10.1038/nm.2392.

13.

Regulation of Mdm2 protein stability and the p53 response by NEDD4-1 E3 ligase.

Xu C, Fan CD, Wang X.

Oncogene. 2015 Jan 15;34(3):281-9. doi: 10.1038/onc.2013.557. Epub 2014 Jan 13.

PMID:
24413081
14.

Ribosomal proteins as unrevealed caretakers for cellular stress and genomic instability.

Kim TH, Leslie P, Zhang Y.

Oncotarget. 2014 Feb 28;5(4):860-71. Review.

15.

GRWD1 negatively regulates p53 via the RPL11-MDM2 pathway and promotes tumorigenesis.

Kayama K, Watanabe S, Takafuji T, Tsuji T, Hironaka K, Matsumoto M, Nakayama KI, Enari M, Kohno T, Shiraishi K, Kiyono T, Yoshida K, Sugimoto N, Fujita M.

EMBO Rep. 2017 Jan;18(1):123-137. doi: 10.15252/embr.201642444. Epub 2016 Nov 17.

PMID:
27856536
16.

Validation of MdmX as a therapeutic target for reactivating p53 in tumors.

Garcia D, Warr MR, Martins CP, Brown Swigart L, Passegué E, Evan GI.

Genes Dev. 2011 Aug 15;25(16):1746-57. doi: 10.1101/gad.16722111.

17.

Protection against High-Fat-Diet-Induced Obesity in MDM2C305F Mice Due to Reduced p53 Activity and Enhanced Energy Expenditure.

Liu S, Kim TH, Franklin DA, Zhang Y.

Cell Rep. 2017 Jan 24;18(4):1005-1018. doi: 10.1016/j.celrep.2016.12.086.

18.

Ribosomal protein S14 unties the MDM2-p53 loop upon ribosomal stress.

Zhou X, Hao Q, Liao J, Zhang Q, Lu H.

Oncogene. 2013 Jan 17;32(3):388-96. doi: 10.1038/onc.2012.63. Epub 2012 Mar 5.

19.

MDM2 binding induces a conformational change in p53 that is opposed by heat-shock protein 90 and precedes p53 proteasomal degradation.

Sasaki M, Nie L, Maki CG.

J Biol Chem. 2007 May 11;282(19):14626-34. Epub 2007 Mar 15. Erratum in: J Biol Chem. 2007 Jun 29;282(26):19272.

20.

Physical and functional interaction between ribosomal protein L11 and the tumor suppressor ARF.

Dai MS, Challagundla KB, Sun XX, Palam LR, Zeng SX, Wek RC, Lu H.

J Biol Chem. 2012 May 18;287(21):17120-9. doi: 10.1074/jbc.M111.311902. Epub 2012 Mar 30.

Supplemental Content

Support Center