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Items: 1 to 20 of 79

1.

Maslinic acid modulates glycogen metabolism by enhancing the insulin signaling pathway and inhibiting glycogen phosphorylase.

Liu J, Wang X, Chen YP, Mao LF, Shang J, Sun HB, Zhang LY.

Chin J Nat Med. 2014 Apr;12(4):259-65. doi: 10.1016/S1875-5364(14)60052-2.

PMID:
24863350
2.

Fumosorinone, a novel PTP1B inhibitor, activates insulin signaling in insulin-resistance HepG2 cells and shows anti-diabetic effect in diabetic KKAy mice.

Liu ZQ, Liu T, Chen C, Li MY, Wang ZY, Chen RS, Wei GX, Wang XY, Luo DQ.

Toxicol Appl Pharmacol. 2015 May 15;285(1):61-70. doi: 10.1016/j.taap.2015.03.011. Epub 2015 Mar 18.

PMID:
25796170
3.

Maslinic acid, a natural inhibitor of glycogen phosphorylase, reduces cerebral ischemic injury in hyperglycemic rats by GLT-1 up-regulation.

Guan T, Qian Y, Tang X, Huang M, Huang L, Li Y, Sun H.

J Neurosci Res. 2011 Nov;89(11):1829-39. doi: 10.1002/jnr.22671. Epub 2011 Jul 28.

PMID:
21800347
4.

Effects of maslinic acid, a natural triterpene, on glycogen metabolism in cultured cortical astrocytes.

Guan T, Li Y, Sun H, Tang X, Qian Y.

Planta Med. 2009 Aug;75(10):1141-3. doi: 10.1055/s-0029-1185481. Epub 2009 Mar 16.

PMID:
19291614
5.

Modified Si-Miao-San extract inhibits inflammatory response and modulates insulin sensitivity in hepatocytes through an IKKβ/IRS-1/Akt-dependent pathway.

Liu K, Luo T, Zhang Z, Wang T, Kou J, Liu B, Huang F.

J Ethnopharmacol. 2011 Jul 14;136(3):473-9. doi: 10.1016/j.jep.2011.01.051. Epub 2011 Feb 4.

PMID:
21296137
6.

Melatonin ameliorates high fat diet-induced diabetes and stimulates glycogen synthesis via a PKCzeta-Akt-GSK3beta pathway in hepatic cells.

Shieh JM, Wu HT, Cheng KC, Cheng JT.

J Pineal Res. 2009 Nov;47(4):339-44. doi: 10.1111/j.1600-079X.2009.00720.x. Epub 2009 Oct 10.

PMID:
19817973
7.

Effects of oleanolic acid on the insulin signaling pathway in skeletal muscle of streptozotocin-induced diabetic male Sprague-Dawley rats.

Mukundwa A, Mukaratirwa S, Masola B.

J Diabetes. 2016 Jan;8(1):98-108. doi: 10.1111/1753-0407.12260. Epub 2015 Mar 4.

PMID:
25564701
8.

Maslinic acid promotes synaptogenesis and axon growth via Akt/GSK-3β activation in cerebral ischemia model.

Qian Y, Huang M, Guan T, Chen L, Cao L, Han XJ, Huang L, Tang X, Li Y, Sun H.

Eur J Pharmacol. 2015 Oct 5;764:298-305. doi: 10.1016/j.ejphar.2015.07.028. Epub 2015 Jul 11.

PMID:
26172083
9.

Insulin receptor deficits in schizophrenia and in cellular and animal models of insulin receptor dysfunction.

Zhao Z, Ksiezak-Reding H, Riggio S, Haroutunian V, Pasinetti GM.

Schizophr Res. 2006 May;84(1):1-14. Epub 2006 Apr 11.

PMID:
16581231
10.
11.

Muscle-specific deletion of the Glut4 glucose transporter alters multiple regulatory steps in glycogen metabolism.

Kim YB, Peroni OD, Aschenbach WG, Minokoshi Y, Kotani K, Zisman A, Kahn CR, Goodyear LJ, Kahn BB.

Mol Cell Biol. 2005 Nov;25(21):9713-23.

12.

Chlorella modulates insulin signaling pathway and prevents high-fat diet-induced insulin resistance in mice.

Vecina JF, Oliveira AG, Araujo TG, Baggio SR, Torello CO, Saad MJ, Queiroz ML.

Life Sci. 2014 Jan 24;95(1):45-52. doi: 10.1016/j.lfs.2013.11.020. Epub 2013 Dec 11.

PMID:
24333277
13.
14.

Adrenaline potentiates insulin-stimulated PKB activation in the rat fast-twitch epitrochlearis muscle without affecting IRS-1-associated PI 3-kinase activity.

Jensen J, Grønning-Wang LM, Jebens E, Whitehead JP, Zorec R, Shepherd PR.

Pflugers Arch. 2008 Aug;456(5):969-78. doi: 10.1007/s00424-008-0471-z. Epub 2008 Feb 26.

PMID:
18299886
15.

Saturated fatty acid-induced miR-195 impairs insulin signaling and glycogen metabolism in HepG2 cells.

Yang WM, Jeong HJ, Park SY, Lee W.

FEBS Lett. 2014 Nov 3;588(21):3939-46. doi: 10.1016/j.febslet.2014.09.006. Epub 2014 Sep 19.

16.

Glycogen phosphorylase inhibitors: a patent review (2008 - 2012).

Gaboriaud-Kolar N, Skaltsounis AL.

Expert Opin Ther Pat. 2013 Aug;23(8):1017-32. doi: 10.1517/13543776.2013.794790. Epub 2013 Apr 30. Review.

PMID:
23627914
17.

Mild electrical stimulation with heat shock ameliorates insulin resistance via enhanced insulin signaling.

Morino S, Kondo T, Sasaki K, Adachi H, Suico MA, Sekimoto E, Matsuda T, Shuto T, Araki E, Kai H.

PLoS One. 2008;3(12):e4068. doi: 10.1371/journal.pone.0004068. Epub 2008 Dec 30.

18.

Cocoa flavonoids attenuate high glucose-induced insulin signalling blockade and modulate glucose uptake and production in human HepG2 cells.

Cordero-Herrera I, Martín MÁ, Goya L, Ramos S.

Food Chem Toxicol. 2014 Feb;64:10-9. doi: 10.1016/j.fct.2013.11.014. Epub 2013 Nov 19.

PMID:
24262486
19.

A refined-JinQi-JiangTang tablet ameliorates prediabetes by reducing insulin resistance and improving beta cell function in mice.

Gao LH, Liu Q, Liu SN, Chen ZY, Li CN, Lei L, Sun SJ, Li LY, Liu JL, Shen ZF.

J Ethnopharmacol. 2014;151(1):675-85. doi: 10.1016/j.jep.2013.11.024. Epub 2013 Nov 25.

PMID:
24286962
20.

Peroxynitrite mediates muscle insulin resistance in mice via nitration of IRbeta/IRS-1 and Akt.

Zhou J, Huang K.

Toxicol Appl Pharmacol. 2009 Nov 15;241(1):101-10. doi: 10.1016/j.taap.2009.08.005. Epub 2009 Aug 12.

PMID:
19682478

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