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Items: 1 to 20 of 151

1.

Lipopeptides are signaled by Toll-like receptor 1, 2 and 6 in endolysosomes.

Motoi Y, Shibata T, Takahashi K, Kanno A, Murakami Y, Li X, Kasahara T, Miyake K.

Int Immunol. 2014 Oct;26(10):563-73. doi: 10.1093/intimm/dxu054.

3.

Surface-expressed TLR6 participates in the recognition of diacylated lipopeptide and peptidoglycan in human cells.

Nakao Y, Funami K, Kikkawa S, Taniguchi M, Nishiguchi M, Fukumori Y, Seya T, Matsumoto M.

J Immunol. 2005 Feb 1;174(3):1566-73.

4.

Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide.

Jin MS, Kim SE, Heo JY, Lee ME, Kim HM, Paik SG, Lee H, Lee JO.

Cell. 2007 Sep 21;130(6):1071-82.

5.

Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer.

Kang JY, Nan X, Jin MS, Youn SJ, Ryu YH, Mah S, Han SH, Lee H, Paik SG, Lee JO.

Immunity. 2009 Dec 18;31(6):873-84. doi: 10.1016/j.immuni.2009.09.018.

6.

Human TLRs 10 and 1 share common mechanisms of innate immune sensing but not signaling.

Guan Y, Ranoa DR, Jiang S, Mutha SK, Li X, Baudry J, Tapping RI.

J Immunol. 2010 May 1;184(9):5094-103. doi: 10.4049/jimmunol.0901888.

7.

Domain exchange between human toll-like receptors 1 and 6 reveals a region required for lipopeptide discrimination.

Omueti KO, Beyer JM, Johnson CM, Lyle EA, Tapping RI.

J Biol Chem. 2005 Nov 4;280(44):36616-25.

8.

TLR1- and TLR6-independent recognition of bacterial lipopeptides.

Buwitt-Beckmann U, Heine H, Wiesmüller KH, Jung G, Brock R, Akira S, Ulmer AJ.

J Biol Chem. 2006 Apr 7;281(14):9049-57.

9.

Vibrio cholerae porin OmpU mediates M1-polarization of macrophages/monocytes via TLR1/TLR2 activation.

Khan J, Sharma PK, Mukhopadhaya A.

Immunobiology. 2015 Nov;220(11):1199-209. doi: 10.1016/j.imbio.2015.06.009.

PMID:
26093918
10.

TLR1/TLR2 heterodimers play an important role in the recognition of Borrelia spirochetes.

Oosting M, Ter Hofstede H, Sturm P, Adema GJ, Kullberg BJ, van der Meer JW, Netea MG, Joosten LA.

PLoS One. 2011;6(10):e25998. doi: 10.1371/journal.pone.0025998.

11.

Heterodimerization of TLR2 with TLR1 or TLR6 expands the ligand spectrum but does not lead to differential signaling.

Farhat K, Riekenberg S, Heine H, Debarry J, Lang R, Mages J, Buwitt-Beckmann U, Röschmann K, Jung G, Wiesmüller KH, Ulmer AJ.

J Leukoc Biol. 2008 Mar;83(3):692-701.

PMID:
18056480
12.

Pegylated bisacycloxypropylcysteine, a diacylated lipopeptide ligand of TLR6, plays a host-protective role against experimental Leishmania major infection.

Pandey SP, Chandel HS, Srivastava S, Selvaraj S, Jha MK, Shukla D, Ebensen T, Guzman CA, Saha B.

J Immunol. 2014 Oct 1;193(7):3632-43. doi: 10.4049/jimmunol.1400672.

13.

The molecular basis for recognition of bacterial ligands at equine TLR2, TLR1 and TLR6.

Irvine KL, Hopkins LJ, Gangloff M, Bryant CE.

Vet Res. 2013 Jul 4;44:50. doi: 10.1186/1297-9716-44-50.

14.

Divergent roles of amino acid residues inside and outside the BB loop affect human Toll-like receptor (TLR)2/2, TLR2/1 and TLR2/6 responsiveness.

Qiu Y, Ding Y, Zou L, Tan Z, Liu T, Fu X, Xu W.

PLoS One. 2013 Apr 23;8(4):e61508. doi: 10.1371/journal.pone.0061508.

15.

Membrane sorting of toll-like receptor (TLR)-2/6 and TLR2/1 heterodimers at the cell surface determines heterotypic associations with CD36 and intracellular targeting.

Triantafilou M, Gamper FG, Haston RM, Mouratis MA, Morath S, Hartung T, Triantafilou K.

J Biol Chem. 2006 Oct 13;281(41):31002-11.

16.

Recognition of lipopeptides by Toll-like receptors.

Takeda K, Takeuchi O, Akira S.

J Endotoxin Res. 2002;8(6):459-63.

PMID:
12697090
17.

Two modes of ligand recognition by TLRs.

Brodsky I, Medzhitov R.

Cell. 2007 Sep 21;130(6):979-81.

18.

Toll-like receptor 6-independent signaling by diacylated lipopeptides.

Buwitt-Beckmann U, Heine H, Wiesmüller KH, Jung G, Brock R, Akira S, Ulmer AJ.

Eur J Immunol. 2005 Jan;35(1):282-9.

19.

Induction of TLR2 expression by inflammatory stimuli is required for endothelial cell responses to lipopeptides.

Satta N, Kruithof EK, Reber G, de Moerloose P.

Mol Immunol. 2008 Nov;46(1):145-57. doi: 10.1016/j.molimm.2008.07.017.

PMID:
18722665
20.

Proinflammatory responses by glycosylphosphatidylinositols (GPIs) of Plasmodium falciparum are mainly mediated through the recognition of TLR2/TLR1.

Zhu J, Krishnegowda G, Li G, Gowda DC.

Exp Parasitol. 2011 Jul;128(3):205-11. doi: 10.1016/j.exppara.2011.03.010.

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