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Items: 1 to 20 of 89

1.

Modulation of the AMPK/Sirt1 axis during neuronal infection by herpes simplex virus type 1.

Martin C, Leyton L, Arancibia Y, Cuevas A, Zambrano A, Concha MI, Otth C.

J Alzheimers Dis. 2014;42(1):301-12. doi: 10.3233/JAD-140237.

PMID:
24858404
2.

Nutraceutical activators of AMPK/Sirt1 axis inhibit viral production and protect neurons from neurodegenerative events triggered during HSV-1 infection.

Leyton L, Hott M, Acuña F, Caroca J, Nuñez M, Martin C, Zambrano A, Concha MI, Otth C.

Virus Res. 2015 Jul 2;205:63-72. doi: 10.1016/j.virusres.2015.05.015. Epub 2015 May 30.

PMID:
26031763
3.
4.

Hepatitis C virus core protein induces hepatic metabolism disorders through down-regulation of the SIRT1-AMPK signaling pathway.

Yu JW, Sun LJ, Liu W, Zhao YH, Kang P, Yan BZ.

Int J Infect Dis. 2013 Jul;17(7):e539-45. doi: 10.1016/j.ijid.2013.01.027. Epub 2013 Mar 16.

5.

The central Sirtuin 1/p53 pathway is essential for the orexigenic action of ghrelin.

Velásquez DA, Martínez G, Romero A, Vázquez MJ, Boit KD, Dopeso-Reyes IG, López M, Vidal A, Nogueiras R, Diéguez C.

Diabetes. 2011 Apr;60(4):1177-85. doi: 10.2337/db10-0802. Epub 2011 Mar 8.

6.

The protective effect of FGF21 on diabetes-induced male germ cell apoptosis is associated with up-regulated testicular AKT and AMPK/Sirt1/PGC-1α signaling.

Jiang X, Chen J, Zhang C, Zhang Z, Tan Y, Feng W, Skibba M, Xin Y, Cai L.

Endocrinology. 2015 Mar;156(3):1156-70. doi: 10.1210/en.2014-1619. Epub 2015 Jan 5.

PMID:
25560828
7.

A novel inverse relationship between metformin-triggered AMPK-SIRT1 signaling and p53 protein abundance in high glucose-exposed HepG2 cells.

Nelson LE, Valentine RJ, Cacicedo JM, Gauthier MS, Ido Y, Ruderman NB.

Am J Physiol Cell Physiol. 2012 Jul 1;303(1):C4-C13. doi: 10.1152/ajpcell.00296.2011. Epub 2012 Feb 29.

8.

Adiponectin promotes pancreatic cancer progression by inhibiting apoptosis via the activation of AMPK/Sirt1/PGC-1α signaling.

Huang B, Cheng X, Wang D, Peng M, Xue Z, Da Y, Zhang N, Yao Z, Li M, Xu A, Zhang R.

Oncotarget. 2014 Jul 15;5(13):4732-45.

9.

SIRT1 promotes proliferation and prevents senescence through targeting LKB1 in primary porcine aortic endothelial cells.

Zu Y, Liu L, Lee MY, Xu C, Liang Y, Man RY, Vanhoutte PM, Wang Y.

Circ Res. 2010 Apr 30;106(8):1384-93. doi: 10.1161/CIRCRESAHA.109.215483. Epub 2010 Mar 4.

PMID:
20203304
10.

Fibroblast growth factor 21 regulates energy metabolism by activating the AMPK-SIRT1-PGC-1alpha pathway.

Chau MD, Gao J, Yang Q, Wu Z, Gromada J.

Proc Natl Acad Sci U S A. 2010 Jul 13;107(28):12553-8. doi: 10.1073/pnas.1006962107. Epub 2010 Jun 28.

11.

SIRT1 activation by methylene blue, a repurposed drug, leads to AMPK-mediated inhibition of steatosis and steatohepatitis.

Shin SY, Kim TH, Wu H, Choi YH, Kim SG.

Eur J Pharmacol. 2014 Mar 15;727:115-24. doi: 10.1016/j.ejphar.2014.01.035. Epub 2014 Jan 30.

PMID:
24486702
12.

Resveratrol modulates tumor cell proliferation and protein translation via SIRT1-dependent AMPK activation.

Lin JN, Lin VC, Rau KM, Shieh PC, Kuo DH, Shieh JC, Chen WJ, Tsai SC, Way TD.

J Agric Food Chem. 2010 Feb 10;58(3):1584-92. doi: 10.1021/jf9035782.

PMID:
19928762
13.

A dietary polyphenol resveratrol acts to provide neuroprotection in recurrent stroke models by regulating AMPK and SIRT1 signaling, thereby reducing energy requirements during ischemia.

Wang LM, Wang YJ, Cui M, Luo WJ, Wang XJ, Barber PA, Chen ZY.

Eur J Neurosci. 2013 May;37(10):1669-81. doi: 10.1111/ejn.12162. Epub 2013 Mar 5. Retraction in: Eur J Neurosci. 2016 Apr;43(7):990.

PMID:
23461657
14.

Activation of AMP-activated protein kinase (AMPK) mediates plumbagin-induced apoptosis and growth inhibition in cultured human colon cancer cells.

Chen MB, Zhang Y, Wei MX, Shen W, Wu XY, Yao C, Lu PH.

Cell Signal. 2013 Oct;25(10):1993-2002. doi: 10.1016/j.cellsig.2013.05.026. Epub 2013 May 25.

PMID:
23712032
15.

SIRT1 and AMPK mediate hypoxia-induced resistance of non-small cell lung cancers to cisplatin and doxorubicin.

Shin DH, Choi YJ, Park JW.

Cancer Res. 2014 Jan 1;74(1):298-308. doi: 10.1158/0008-5472.CAN-13-2620. Epub 2013 Nov 15.

16.

SIRT1 regulates Tat-induced HIV-1 transactivation through activating AMP-activated protein kinase.

Zhang HS, Wu MR.

Virus Res. 2009 Dec;146(1-2):51-7. doi: 10.1016/j.virusres.2009.08.005. Epub 2009 Aug 29.

PMID:
19720090
17.
18.

Sirt1 attenuates camptothecin-induced apoptosis through caspase-3 pathway in porcine preadipocytes.

Pang WJ, Xiong Y, Wang Y, Tong Q, Yang GS.

Exp Cell Res. 2013 Mar 10;319(5):670-83. doi: 10.1016/j.yexcr.2012.12.025. Epub 2013 Jan 9.

PMID:
23313858
19.

SIRT1-dependent AMPK pathway in the protection of estrogen against ischemic brain injury.

Guo JM, Shu H, Wang L, Xu JJ, Niu XC, Zhang L.

CNS Neurosci Ther. 2017 Apr;23(4):360-369. doi: 10.1111/cns.12686. Epub 2017 Mar 2.

PMID:
28256111
20.

SIRT1 confers protection against UVB- and H2O2-induced cell death via modulation of p53 and JNK in cultured skin keratinocytes.

Cao C, Lu S, Kivlin R, Wallin B, Card E, Bagdasarian A, Tamakloe T, Wang WJ, Song X, Chu WM, Kouttab N, Xu A, Wan Y.

J Cell Mol Med. 2009 Sep;13(9B):3632-43. doi: 10.1111/j.1582-4934.2008.00453.x. Epub 2008 Aug 4.

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