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Items: 1 to 20 of 101

1.

Gramicidin D enhances the antibacterial activity of fluoride.

Nelson JW, Zhou Z, Breaker RR.

Bioorg Med Chem Lett. 2014 Jul 1;24(13):2969-2971. doi: 10.1016/j.bmcl.2014.03.061. Epub 2014 Mar 28.

2.

Small molecule fluoride toxicity agonists.

Nelson JW, Plummer MS, Blount KF, Ames TD, Breaker RR.

Chem Biol. 2015 Apr 23;22(4):527-534. doi: 10.1016/j.chembiol.2015.03.016.

3.

Solubilized gramicidin A as potential systemic antibiotics.

Wang F, Qin L, Pace CJ, Wong P, Malonis R, Gao J.

Chembiochem. 2012 Jan 2;13(1):51-5. doi: 10.1002/cbic.201100671. Epub 2011 Nov 24. No abstract available.

PMID:
22113881
4.

Modulation of structure and antibacterial and hemolytic activity by ring size in cyclic gramicidin S analogs.

Kondejewski LH, Farmer SW, Wishart DS, Kay CM, Hancock RE, Hodges RS.

J Biol Chem. 1996 Oct 11;271(41):25261-8.

5.

[Action of different types of gramicidin S derivatives on bacterial cells and protoplasts].

Bulgakova VG, Petrykina ZM, Korolev PN, Sazykina SIu, Polin AN.

Mikrobiologiia. 1985 Jul-Aug;54(4):621-7. Russian.

PMID:
2414637
6.

Synthesis and biological evaluation of gramicidin S dimers.

Grotenbreg GM, Witte MD, van Hoof PA, Spalburg E, Reiss P, Noort D, de Neeling AJ, Koert U, van der Marel GA, Overkleeft HS, Overhand M.

Org Biomol Chem. 2005 Jan 21;3(2):233-8.

PMID:
15717418
7.

Evaluation of readily accessible azoles as mimics of the aromatic ring of D-phenylalanine in the turn region of gramicidin S.

van der Knaap M, Lageveen LT, Busscher HJ, Mars-Groenendijk R, Noort D, Otero JM, Llamas-Saiz AL, van Raaij MJ, van der Marel GA, Overkleeft HS, Overhand M.

ChemMedChem. 2011 May 2;6(5):840-7. doi: 10.1002/cmdc.201000539. Epub 2011 Mar 11.

PMID:
21400662
8.

Sequence inversion and phenylalanine surrogates at the beta-turn enhance the antibiotic activity of gramicidin S.

Solanas C, de la Torre BG, Fernández-Reyes M, Santiveri CM, Jiménez MA, Rivas L, Jiménez AI, Andreu D, Cativiela C.

J Med Chem. 2010 May 27;53(10):4119-29. doi: 10.1021/jm100143f.

9.

'Inverted' analogs of the antibiotic gramicidin S with an improved biological profile.

Kapoerchan VV, Knijnenburg AD, Keizer P, Spalburg E, de Neeling AJ, Mars-Groenendijk RH, Noort D, Otero JM, Llamas-Saiz AL, van Raaij MJ, van der Marel GA, Overkleeft HS, Overhand M.

Bioorg Med Chem. 2012 Oct 15;20(20):6059-62. doi: 10.1016/j.bmc.2012.08.038. Epub 2012 Aug 31.

PMID:
22989907
10.

A novel active analogue of gramicidin S with smaller ring size.

Tamaki M, Ishii R, Kikuchi S, Watanabe E.

J Antibiot (Tokyo). 2005 Apr;58(4):293-5.

PMID:
15981419
11.

Synthesis, biological activity and solution structure of new analogues of the antimicrobial Gramicidin S.

Kamysz E, Mickiewicz B, Kamysz W, Bielińska S, Rodziewicz-Motowidło S, Ciarkowski J.

J Pept Sci. 2011 Mar;17(3):211-7. doi: 10.1002/psc.1314. Epub 2010 Oct 25.

PMID:
21308877
12.
13.

Gramicidin S analogs having six basic amino acid residues.

Tamaki M, Sasaki I, Nakao Y, Shindo M, Kimura M, Uchida Y.

J Antibiot (Tokyo). 2009 Oct;62(10):597-9. doi: 10.1038/ja.2009.81. Epub 2009 Aug 28. No abstract available.

PMID:
19713990
14.

Synthesis and biological evaluation of asymmetric gramicidin S analogues containing modified D-phenylalanine residues.

van der Knaap M, Engels E, Busscher HJ, Otero JM, Llamas-Saiz AL, van Raaij MJ, Mars-Groenendijk RH, Noort D, van der Marel GA, Overkleeft HS, Overhand M.

Bioorg Med Chem. 2009 Sep 1;17(17):6318-28. doi: 10.1016/j.bmc.2009.07.042. Epub 2009 Jul 25.

PMID:
19674904
15.

Novel cycloundecapeptides related to gramicidin S with both high antibiotic activity and low hemolytic activity.

Tamaki M, Takanashi K, Harada T, Fujinuma K, Shindo M, Kimura M, Uchida Y.

Chem Pharm Bull (Tokyo). 2011;59(12):1481-4.

17.

Preparation and properties of novel gramicidin S analogs possessing a tri-, tetra- or pentamethylene bridge between ornithine side chains.

Yamada K, Ando K, Takahashi Y, Oda Y, Yamamura H, Araki S, Kobayashi K, Katakai R, Kato F, Kawai M.

J Pept Res. 1999 Jun;53(6):611-7.

PMID:
10408334
18.

An adamantyl amino acid containing gramicidin S analogue with broad spectrum antibacterial activity and reduced hemolytic activity.

Kapoerchan VV, Knijnenburg AD, Niamat M, Spalburg E, de Neeling AJ, Nibbering PH, Mars-Groenendijk RH, Noort D, Otero JM, Llamas-Saiz AL, van Raaij MJ, van der Marel GA, Overkleeft HS, Overhand M.

Chemistry. 2010 Oct 25;16(40):12174-81. doi: 10.1002/chem.201001686.

PMID:
20848624
19.

Syntheses and antibacterial activities of gramicidin S analogs containing L-ornithine in place of L-valine.

Soejima Y, Hashiguchi A, Izumiya N.

Biosci Biotechnol Biochem. 1994 May;58(5):826-9.

20.

Synthesis of low-hemolytic antimicrobial dehydropeptides based on gramicidin s.

Yamada K, Shinoda SS, Oku H, Komagoe K, Katsu T, Katakai R.

J Med Chem. 2006 Dec 28;49(26):7592-5.

PMID:
17181140

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