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Items: 1 to 20 of 75

1.

miR-155 activates cytokine gene expression in Th17 cells by regulating the DNA-binding protein Jarid2 to relieve polycomb-mediated repression.

Escobar TM, Kanellopoulou C, Kugler DG, Kilaru G, Nguyen CK, Nagarajan V, Bhairavabhotla RK, Northrup D, Zahr R, Burr P, Liu X, Zhao K, Sher A, Jankovic D, Zhu J, Muljo SA.

Immunity. 2014 Jun 19;40(6):865-79. doi: 10.1016/j.immuni.2014.03.014. Epub 2014 May 22.

2.

Jarid2 links MicroRNA and chromatin in Th17 cells.

Merkenschlager M.

Immunity. 2014 Jun 19;40(6):855-6. doi: 10.1016/j.immuni.2014.06.004.

3.

Jarid2 is induced by TCR signalling and controls iNKT cell maturation.

Pereira RM, Martinez GJ, Engel I, Cruz-Guilloty F, Barboza BA, Tsagaratou A, Lio CW, Berg LJ, Lee Y, Kronenberg M, Bandukwala HS, Rao A.

Nat Commun. 2014 Aug 8;5:4540. doi: 10.1038/ncomms5540.

4.

Ikaros sets the potential for Th17 lineage gene expression through effects on chromatin state in early T cell development.

Wong LY, Hatfield JK, Brown MA.

J Biol Chem. 2013 Dec 6;288(49):35170-9. doi: 10.1074/jbc.M113.481440. Epub 2013 Oct 21.

5.

MiR-155 contributes to Th17 cells differentiation in dextran sulfate sodium (DSS)-induced colitis mice via Jarid2.

Xu M, Zuo D, Liu X, Fan H, Chen Q, Deng S, Shou Z, Tang Q, Yang J, Nan Z, Wu H, Dong Y, Liu Y.

Biochem Biophys Res Commun. 2017 Jun 17;488(1):6-14. doi: 10.1016/j.bbrc.2017.04.143. Epub 2017 Apr 28.

PMID:
28461115
6.

Blockade of interleukin-6 signaling suppresses not only th17 but also interphotoreceptor retinoid binding protein-specific Th1 by promoting regulatory T cells in experimental autoimmune uveoretinitis.

Haruta H, Ohguro N, Fujimoto M, Hohki S, Terabe F, Serada S, Nomura S, Nishida K, Kishimoto T, Naka T.

Invest Ophthalmol Vis Sci. 2011 May 17;52(6):3264-71. doi: 10.1167/iovs.10-6272.

PMID:
21330657
7.

The histone H3 lysine-27 demethylase Jmjd3 plays a critical role in specific regulation of Th17 cell differentiation.

Liu Z, Cao W, Xu L, Chen X, Zhan Y, Yang Q, Liu S, Chen P, Jiang Y, Sun X, Tao Y, Hu Y, Li C, Wang Q, Wang Y, Chen CD, Shi Y, Zhang X.

J Mol Cell Biol. 2015 Dec;7(6):505-16. doi: 10.1093/jmcb/mjv022. Epub 2015 Apr 3.

PMID:
25840993
8.

PRC2 complexes with JARID2, MTF2, and esPRC2p48 in ES cells to modulate ES cell pluripotency and somatic cell reprogramming.

Zhang Z, Jones A, Sun CW, Li C, Chang CW, Joo HY, Dai Q, Mysliwiec MR, Wu LC, Guo Y, Yang W, Liu K, Pawlik KM, Erdjument-Bromage H, Tempst P, Lee Y, Min J, Townes TM, Wang H.

Stem Cells. 2011 Feb;29(2):229-40. doi: 10.1002/stem.578.

9.

Regulation of the MIR155 host gene in physiological and pathological processes.

Elton TS, Selemon H, Elton SM, Parinandi NL.

Gene. 2013 Dec 10;532(1):1-12. doi: 10.1016/j.gene.2012.12.009. Epub 2012 Dec 14. Review.

PMID:
23246696
10.

EZH2 is crucial for both differentiation of regulatory T cells and T effector cell expansion.

Yang XP, Jiang K, Hirahara K, Vahedi G, Afzali B, Sciume G, Bonelli M, Sun HW, Jankovic D, Kanno Y, Sartorelli V, O'Shea JJ, Laurence A.

Sci Rep. 2015 Jun 19;5:10643. doi: 10.1038/srep10643.

11.

Immunoproteasome subunit LMP7 deficiency and inhibition suppresses Th1 and Th17 but enhances regulatory T cell differentiation.

Kalim KW, Basler M, Kirk CJ, Groettrup M.

J Immunol. 2012 Oct 15;189(8):4182-93. doi: 10.4049/jimmunol.1201183. Epub 2012 Sep 14.

12.

De novo DNA methylation is required to restrict T helper lineage plasticity.

Thomas RM, Gamper CJ, Ladle BH, Powell JD, Wells AD.

J Biol Chem. 2012 Jun 29;287(27):22900-9. doi: 10.1074/jbc.M111.312785. Epub 2012 May 14.

13.

Invariant NKT cells regulate experimental autoimmune uveitis through inhibition of Th17 differentiation.

Oh K, Byoun OJ, Ham DI, Kim YS, Lee DS.

Eur J Immunol. 2011 Feb;41(2):392-402. doi: 10.1002/eji.201040569. Epub 2010 Dec 29.

14.

Demethylation of H3K27 Is Essential for the Induction of Direct Cardiac Reprogramming by miR Combo.

Dal-Pra S, Hodgkinson CP, Mirotsou M, Kirste I, Dzau VJ.

Circ Res. 2017 Apr 28;120(9):1403-1413. doi: 10.1161/CIRCRESAHA.116.308741. Epub 2017 Feb 16.

PMID:
28209718
15.

Inhibition of inflammatory CD4 T cell activity by murine liver sinusoidal endothelial cells.

Carambia A, Frenzel C, Bruns OT, Schwinge D, Reimer R, Hohenberg H, Huber S, Tiegs G, Schramm C, Lohse AW, Herkel J.

J Hepatol. 2013 Jan;58(1):112-8. doi: 10.1016/j.jhep.2012.09.008. Epub 2012 Sep 16.

PMID:
22989568
16.

IL-12 inhibits the TGF-β-dependent T cell developmental programs and skews the TGF-β-induced differentiation into a Th1-like direction.

Prochazkova J, Pokorna K, Holan V.

Immunobiology. 2012 Jan;217(1):74-82. doi: 10.1016/j.imbio.2011.07.032. Epub 2011 Aug 5.

PMID:
21903294
17.

The polycomb repressive complex 2 governs life and death of peripheral T cells.

Zhang Y, Kinkel S, Maksimovic J, Bandala-Sanchez E, Tanzer MC, Naselli G, Zhang JG, Zhan Y, Lew AM, Silke J, Oshlack A, Blewitt ME, Harrison LC.

Blood. 2014 Jul 31;124(5):737-49. doi: 10.1182/blood-2013-12-544106. Epub 2014 Jun 20.

18.

STAT3 activates miR-155 in Th17 cells and acts in concert to promote experimental autoimmune uveitis.

Escobar T, Yu CR, Muljo SA, Egwuagu CE.

Invest Ophthalmol Vis Sci. 2013 Jun 10;54(6):4017-25. doi: 10.1167/iovs.13-11937.

19.

MicroRNA-155 deficiency results in decreased macrophage inflammation and attenuated atherogenesis in apolipoprotein E-deficient mice.

Du F, Yu F, Wang Y, Hui Y, Carnevale K, Fu M, Lu H, Fan D.

Arterioscler Thromb Vasc Biol. 2014 Apr;34(4):759-67. doi: 10.1161/ATVBAHA.113.302701. Epub 2014 Feb 6.

20.

miR26a modulates Th17/T reg balance in the EAE model of multiple sclerosis by targeting IL6.

Zhang R, Tian A, Wang J, Shen X, Qi G, Tang Y.

Neuromolecular Med. 2015 Mar;17(1):24-34. doi: 10.1007/s12017-014-8335-5. Epub 2014 Nov 2.

PMID:
25362566

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