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Items: 1 to 20 of 129

1.

The kidney is the principal organ mediating klotho effects.

Lindberg K, Amin R, Moe OW, Hu MC, Erben RG, Östman Wernerson A, Lanske B, Olauson H, Larsson TE.

J Am Soc Nephrol. 2014 Oct;25(10):2169-75. doi: 10.1681/ASN.2013111209. Epub 2014 May 22.

2.

Targeted deletion of Klotho in kidney distal tubule disrupts mineral metabolism.

Olauson H, Lindberg K, Amin R, Jia T, Wernerson A, Andersson G, Larsson TE.

J Am Soc Nephrol. 2012 Oct;23(10):1641-51. Epub 2012 Aug 9.

3.

Klotho expression in long bones regulates FGF23 production during renal failure.

Kaludjerovic J, Komaba H, Sato T, Erben RG, Baron R, Olauson H, Larsson TE, Lanske B.

FASEB J. 2017 May;31(5):2050-2064. doi: 10.1096/fj.201601036R. Epub 2017 Feb 9.

PMID:
28183805
4.

Klotho ablation converts the biochemical and skeletal alterations in FGF23 (R176Q) transgenic mice to a Klotho-deficient phenotype.

Bai X, Dinghong Q, Miao D, Goltzman D, Karaplis AC.

Am J Physiol Endocrinol Metab. 2009 Jan;296(1):E79-88. doi: 10.1152/ajpendo.90539.2008. Epub 2008 Nov 4.

5.

[Discovery of alpha-Klotho and FGF23 unveiled new insight into calcium and phosphate homeostasis].

Nabeshima Y.

Clin Calcium. 2008 Jul;18(7):923-34. doi: CliCa0807923934. Review. Japanese.

PMID:
18591743
6.

Klotho as a regulator of fibroblast growth factor signaling and phosphate/calcium metabolism.

Kuro-o M.

Curr Opin Nephrol Hypertens. 2006 Jul;15(4):437-41. Review.

PMID:
16775459
7.

Stanniocalcin 2 is associated with ectopic calcification in α-klotho mutant mice and inhibits hyperphosphatemia-induced calcification in aortic vascular smooth muscle cells.

Takei Y, Yamamoto H, Sato T, Otani A, Kozai M, Masuda M, Taketani Y, Muto-Sato K, Lanske B, Takeda E.

Bone. 2012 Apr;50(4):998-1005. doi: 10.1016/j.bone.2012.01.006. Epub 2012 Jan 21.

PMID:
22285620
8.

Klotho: an antiaging protein involved in mineral and vitamin D metabolism.

Torres PU, Prié D, Molina-Blétry V, Beck L, Silve C, Friedlander G.

Kidney Int. 2007 Apr;71(8):730-7. Epub 2007 Feb 28. Review.

10.

[Role of parathyroid hormone in Klotho-FGF23 system].

Kimura T, Shiizaki K, Kuro-O M.

Clin Calcium. 2016 Jun;26(6):859-66. doi: CliCa1606859866. Japanese.

PMID:
27230841
11.

[alpha Klotho and inorganic phosphate metabolism].

Miyamoto K, Segawa H, Ito M, Tatsumi S.

Clin Calcium. 2007 May;17(5):698-703. Review. Japanese.

PMID:
17470998
12.

Parathyroid-specific deletion of Klotho unravels a novel calcineurin-dependent FGF23 signaling pathway that regulates PTH secretion.

Olauson H, Lindberg K, Amin R, Sato T, Jia T, Goetz R, Mohammadi M, Andersson G, Lanske B, Larsson TE.

PLoS Genet. 2013;9(12):e1003975. doi: 10.1371/journal.pgen.1003975. Epub 2013 Dec 12.

13.

Klotho gene, phosphocalcic metabolism, and survival in dialysis.

Torres PU, Prié D, Beck L, De Brauwere D, Leroy C, Friedlander G.

J Ren Nutr. 2009 Jan;19(1):50-6. doi: 10.1053/j.jrn.2008.10.018. Review.

PMID:
19121771
14.

In vivo genetic evidence for klotho-dependent, fibroblast growth factor 23 (Fgf23) -mediated regulation of systemic phosphate homeostasis.

Nakatani T, Sarraj B, Ohnishi M, Densmore MJ, Taguchi T, Goetz R, Mohammadi M, Lanske B, Razzaque MS.

FASEB J. 2009 Feb;23(2):433-41. doi: 10.1096/fj.08-114397. Epub 2008 Oct 3.

15.

The Role of Klotho Protein in Chronic Kidney Disease: Studies in Animals and Humans.

Gołembiewska E, Stępniewska J, Kabat-Koperska J, Kędzierska K, Domański M, Ciechanowski K.

Curr Protein Pept Sci. 2016;17(8):821-826. Review.

PMID:
27226196
16.

Role of Klotho in aging, phosphate metabolism, and CKD.

John GB, Cheng CY, Kuro-o M.

Am J Kidney Dis. 2011 Jul;58(1):127-34. doi: 10.1053/j.ajkd.2010.12.027. Epub 2011 Apr 15. Review.

17.

Klotho and chronic kidney disease.

Hu MC, Kuro-o M, Moe OW.

Contrib Nephrol. 2013;180:47-63. doi: 10.1159/000346778. Epub 2013 May 3. Review.

18.

Klotho lacks a vitamin D independent physiological role in glucose homeostasis, bone turnover, and steady-state PTH secretion in vivo.

Anour R, Andrukhova O, Ritter E, Zeitz U, Erben RG.

PLoS One. 2012;7(2):e31376. doi: 10.1371/journal.pone.0031376. Epub 2012 Feb 3.

19.

Arterial klotho expression and FGF23 effects on vascular calcification and function.

Lindberg K, Olauson H, Amin R, Ponnusamy A, Goetz R, Taylor RF, Mohammadi M, Canfield A, Kublickiene K, Larsson TE.

PLoS One. 2013;8(4):e60658. doi: 10.1371/journal.pone.0060658. Epub 2013 Apr 5.

20.

Acetazolamide sensitive tissue calcification and aging of klotho-hypomorphic mice.

Leibrock CB, Alesutan I, Voelkl J, Michael D, Castor T, Kohlhofer U, Quintanilla-Martinez L, Kübler L, Mannheim JG, Pichler BJ, Rosenblatt KP, Kuro-o M, Lang F.

J Mol Med (Berl). 2016 Jan;94(1):95-106. doi: 10.1007/s00109-015-1331-x. Epub 2015 Aug 27.

PMID:
26307633

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