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Items: 1 to 20 of 327

1.

Hepatocyte specific deletion of c-Met leads to the development of severe non-alcoholic steatohepatitis in mice.

Kroy DC, Schumacher F, Ramadori P, Hatting M, Bergheim I, Gassler N, Boekschoten MV, Müller M, Streetz KL, Trautwein C.

J Hepatol. 2014 Oct;61(4):883-90. doi: 10.1016/j.jhep.2014.05.019. Epub 2014 May 15.

PMID:
24845607
2.

c-Met confers protection against chronic liver tissue damage and fibrosis progression after bile duct ligation in mice.

Giebeler A, Boekschoten MV, Klein C, Borowiak M, Birchmeier C, Gassler N, Wasmuth HE, Müller M, Trautwein C, Streetz KL.

Gastroenterology. 2009 Jul;137(1):297-308, 308.e1-4. doi: 10.1053/j.gastro.2009.01.068. Epub 2009 Feb 5.

PMID:
19208365
3.

Caspase-1-mediated regulation of fibrogenesis in diet-induced steatohepatitis.

Dixon LJ, Berk M, Thapaliya S, Papouchado BG, Feldstein AE.

Lab Invest. 2012 May;92(5):713-23. doi: 10.1038/labinvest.2012.45. Epub 2012 Mar 12.

4.

Lipid metabolism, oxidative stress and cell death are regulated by PKC delta in a dietary model of nonalcoholic steatohepatitis.

Greene MW, Burrington CM, Lynch DT, Davenport SK, Johnson AK, Horsman MJ, Chowdhry S, Zhang J, Sparks JD, Tirrell PC.

PLoS One. 2014 Jan 15;9(1):e85848. doi: 10.1371/journal.pone.0085848. eCollection 2014.

5.

Caspase 3 inactivation protects against hepatic cell death and ameliorates fibrogenesis in a diet-induced NASH model.

Thapaliya S, Wree A, Povero D, Inzaugarat ME, Berk M, Dixon L, Papouchado BG, Feldstein AE.

Dig Dis Sci. 2014 Jun;59(6):1197-206. doi: 10.1007/s10620-014-3167-6. Epub 2014 May 3.

6.

Mouse models of diet-induced nonalcoholic steatohepatitis reproduce the heterogeneity of the human disease.

Machado MV, Michelotti GA, Xie G, Almeida Pereira T, Boursier J, Bohnic B, Guy CD, Diehl AM.

PLoS One. 2015 May 27;10(5):e0127991. doi: 10.1371/journal.pone.0127991. eCollection 2015. Erratum in: PLoS One. 2015;10(6):e0132315. de Almeida, Thiago Pereira [corrected to Almeida Pereira, Thiago].

7.

Reduced lipoapoptosis, hedgehog pathway activation and fibrosis in caspase-2 deficient mice with non-alcoholic steatohepatitis.

Machado MV, Michelotti GA, Pereira Tde A, Boursier J, Kruger L, Swiderska-Syn M, Karaca G, Xie G, Guy CD, Bohinc B, Lindblom KR, Johnson E, Kornbluth S, Diehl AM.

Gut. 2015 Jul;64(7):1148-57. doi: 10.1136/gutjnl-2014-307362. Epub 2014 Jul 22.

8.

Necroptosis is a key pathogenic event in human and experimental murine models of non-alcoholic steatohepatitis.

Afonso MB, Rodrigues PM, Carvalho T, Caridade M, Borralho P, Cortez-Pinto H, Castro RE, Rodrigues CM.

Clin Sci (Lond). 2015 Oct 1;129(8):721-39. doi: 10.1042/CS20140732. Epub 2015 Jun 15.

PMID:
26201023
9.

Hepatocyte caspase-8 is an essential modulator of steatohepatitis in rodents.

Hatting M, Zhao G, Schumacher F, Sellge G, Al Masaoudi M, Gaβler N, Boekschoten M, Müller M, Liedtke C, Cubero FJ, Trautwein C.

Hepatology. 2013 Jun;57(6):2189-201. doi: 10.1002/hep.26271. Epub 2013 May 6.

PMID:
23339067
10.

Genetic Nrf2 Overactivation Inhibits the Deleterious Effects Induced by Hepatocyte-Specific c-met Deletion during the Progression of NASH.

Ramadori P, Drescher H, Erschfeld S, Fragoulis A, Kensler TW, Wruck CJ, Cubero FJ, Trautwein C, Streetz KL, Kroy DC.

Oxid Med Cell Longev. 2017;2017:3420286. doi: 10.1155/2017/3420286. Epub 2017 Jun 6.

11.

p16 deficiency promotes nonalcoholic steatohepatitis via regulation of hepatic oxidative stress.

Lv F, Wu J, Miao D, An W, Wang Y.

Biochem Biophys Res Commun. 2017 Apr 29;486(2):264-269. doi: 10.1016/j.bbrc.2017.03.023. Epub 2017 Mar 10.

PMID:
28286271
12.

Sitagliptin attenuates methionine/choline-deficient diet-induced steatohepatitis.

Jung YA, Choi YK, Jung GS, Seo HY, Kim HS, Jang BK, Kim JG, Lee IK, Kim MK, Park KG.

Diabetes Res Clin Pract. 2014 Jul;105(1):47-57. doi: 10.1016/j.diabres.2014.04.028. Epub 2014 May 1.

PMID:
24842243
13.

β7-Integrin and MAdCAM-1 play opposing roles during the development of non-alcoholic steatohepatitis.

Drescher HK, Schippers A, Clahsen T, Sahin H, Noels H, Hornef M, Wagner N, Trautwein C, Streetz KL, Kroy DC.

J Hepatol. 2017 Jun;66(6):1251-1264. doi: 10.1016/j.jhep.2017.02.001. Epub 2017 Feb 10.

PMID:
28192190
14.

Pan-caspase inhibitor VX-166 reduces fibrosis in an animal model of nonalcoholic steatohepatitis.

Witek RP, Stone WC, Karaca FG, Syn WK, Pereira TA, Agboola KM, Omenetti A, Jung Y, Teaberry V, Choi SS, Guy CD, Pollard J, Charlton P, Diehl AM.

Hepatology. 2009 Nov;50(5):1421-30. doi: 10.1002/hep.23167.

PMID:
19676126
15.

Attenuated progression of diet-induced steatohepatitis in glutathione-deficient mice.

Haque JA, McMahan RS, Campbell JS, Shimizu-Albergine M, Wilson AM, Botta D, Bammler TK, Beyer RP, Montine TJ, Yeh MM, Kavanagh TJ, Fausto N.

Lab Invest. 2010 Dec;90(12):1704-17. doi: 10.1038/labinvest.2010.112. Epub 2010 Jun 14.

16.

Activation of the Nrf2-ARE pathway in hepatocytes protects against steatosis in nutritionally induced non-alcoholic steatohepatitis in mice.

Lee LY, Köhler UA, Zhang L, Roenneburg D, Werner S, Johnson JA, Foley DP.

Toxicol Sci. 2014 Dec;142(2):361-74. doi: 10.1093/toxsci/kfu184. Epub 2014 Oct 6.

17.

Fatty acids in non-alcoholic steatohepatitis: Focus on pentadecanoic acid.

Yoo W, Gjuka D, Stevenson HL, Song X, Shen H, Yoo SY, Wang J, Fallon M, Ioannou GN, Harrison SA, Beretta L.

PLoS One. 2017 Dec 15;12(12):e0189965. doi: 10.1371/journal.pone.0189965. eCollection 2017.

18.

NF-κB1 deficiency stimulates the progression of non-alcoholic steatohepatitis (NASH) in mice by promoting NKT-cell-mediated responses.

Locatelli I, Sutti S, Vacchiano M, Bozzola C, Albano E.

Clin Sci (Lond). 2013 Feb;124(4):279-87. doi: 10.1042/CS20120289.

PMID:
22970906
19.

[The role of apoptosis and the related genes in non-alcoholic steatohepatitis].

Nan YM, Wu WJ, Yao XX, Wang L.

Zhonghua Gan Zang Bing Za Zhi. 2007 Jan;15(1):41-6. Chinese.

PMID:
17244458
20.

Myeloperoxidase-Hepatocyte-Stellate Cell Cross Talk Promotes Hepatocyte Injury and Fibrosis in Experimental Nonalcoholic Steatohepatitis.

Pulli B, Ali M, Iwamoto Y, Zeller MW, Schob S, Linnoila JJ, Chen JW.

Antioxid Redox Signal. 2015 Dec 1;23(16):1255-69. doi: 10.1089/ars.2014.6108. Epub 2015 Jun 24.

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