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Items: 1 to 20 of 107

1.

CD80 and CD86 IgC domains are important for quaternary structure, receptor binding and co-signaling function.

Girard T, Gaucher D, El-Far M, Breton G, Sékaly RP.

Immunol Lett. 2014 Sep;161(1):65-75. doi: 10.1016/j.imlet.2014.05.002. Epub 2014 May 15.

PMID:
24845157
2.

Both extracellular immunoglobin-like domains of CD80 contain residues critical for binding T cell surface receptors CTLA-4 and CD28.

Peach RJ, Bajorath J, Naemura J, Leytze G, Greene J, Aruffo A, Linsley PS.

J Biol Chem. 1995 Sep 8;270(36):21181-7.

3.

Activation of human peripheral blood dendritic cells induces the CD86 co-stimulatory molecule.

McLellan AD, Starling GC, Williams LA, Hock BD, Hart DN.

Eur J Immunol. 1995 Jul;25(7):2064-8. Erratum in: Eur J Immunol 1995 Dec;25(12):3525.

PMID:
7542604
4.

Interactions of CD80 and CD86 with CD28 and CTLA4.

Ellis JH, Burden MN, Vinogradov DV, Linge C, Crowe JS.

J Immunol. 1996 Apr 15;156(8):2700-9.

PMID:
8609386
5.

The IgV domain of human B7-2 (CD86) is sufficient to co-stimulate T lymphocytes and induce cytokine secretion.

Rennert P, Furlong K, Jellis C, Greenfield E, Freeman GJ, Ueda Y, Levine B, June CH, Gray GS.

Int Immunol. 1997 Jun;9(6):805-13.

6.

CD80 and CD86 C domains play an important role in receptor binding and co-stimulatory properties.

Vasu C, Wang A, Gorla SR, Kaithamana S, Prabhakar BS, Holterman MJ.

Int Immunol. 2003 Feb;15(2):167-75.

7.

Chimeric co-stimulatory molecules that selectively act through CD28 or CTLA-4 on human T cells.

Lazetic S, Leong SR, Chang JC, Ong R, Dawes G, Punnonen J.

J Biol Chem. 2002 Oct 11;277(41):38660-8. Epub 2002 Aug 6.

8.

Differential effects of CTLA-4 substitutions on the binding of human CD80 (B7-1) and CD86 (B7-2).

Morton PA, Fu XT, Stewart JA, Giacoletto KS, White SL, Leysath CE, Evans RJ, Shieh JJ, Karr RW.

J Immunol. 1996 Feb 1;156(3):1047-54.

PMID:
8557978
9.
10.

Covalent dimerization of CD28/CTLA-4 and oligomerization of CD80/CD86 regulate T cell costimulatory interactions.

Greene JL, Leytze GM, Emswiler J, Peach R, Bajorath J, Cosand W, Linsley PS.

J Biol Chem. 1996 Oct 25;271(43):26762-71.

11.
12.

Differential recognition by CD28 of its cognate counter receptors CD80 (B7.1) and B70 (B7.2): analysis by site directed mutagenesis.

Truneh A, Reddy M, Ryan P, Lyn SD, Eichman C, Couez D, Hurle MR, Sekaly RP, Olive D, Sweet R.

Mol Immunol. 1996 Feb;33(3):321-34.

PMID:
8649453
13.

CD28/CTLA-4 and CD80/CD86 families: signaling and function.

Slavik JM, Hutchcroft JE, Bierer BE.

Immunol Res. 1999;19(1):1-24. Review.

PMID:
10374692
15.

Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors.

Linsley PS, Greene JL, Brady W, Bajorath J, Ledbetter JA, Peach R.

Immunity. 1994 Dec;1(9):793-801. Erratum in: Immunity 1995 Feb;2(2):following 203.

PMID:
7534620
16.

Genomic organization of the gene coding for the costimulatory human B-lymphocyte antigen B7-2 (CD86).

Jellis CL, Wang SS, Rennert P, Borriello F, Sharpe AH, Green NR, Gray GS.

Immunogenetics. 1995;42(2):85-9.

PMID:
7541777
17.

Identification of residues in the V domain of CD80 (B7-1) implicated in functional interactions with CD28 and CTLA4.

Fargeas CA, Truneh A, Reddy M, Hurle M, Sweet R, Sékaly RP.

J Exp Med. 1995 Sep 1;182(3):667-75.

18.

Affinity and cross-reactivity engineering of CTLA4-Ig to modulate T cell costimulation.

Xu Z, Juan V, Ivanov A, Ma Z, Polakoff D, Powers DB, Dubridge RB, Wilson K, Akamatsu Y.

J Immunol. 2012 Nov 1;189(9):4470-7. doi: 10.4049/jimmunol.1201813. Epub 2012 Sep 26.

19.

CD80 and CD86 are not equivalent in their ability to induce the tyrosine phosphorylation of CD28.

Slavik JM, Hutchcroft JE, Bierer BE.

J Biol Chem. 1999 Jan 29;274(5):3116-24.

20.

NK cell triggering by the human costimulatory molecules CD80 and CD86.

Wilson JL, Charo J, Martín-Fontecha A, Dellabona P, Casorati G, Chambers BJ, Kiessling R, Bejarano MT, Ljunggren HG.

J Immunol. 1999 Oct 15;163(8):4207-12.

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