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Items: 1 to 20 of 123

1.

Cardiac-specific YAP activation improves cardiac function and survival in an experimental murine MI model.

Lin Z, von Gise A, Zhou P, Gu F, Ma Q, Jiang J, Yau AL, Buck JN, Gouin KA, van Gorp PR, Zhou B, Chen J, Seidman JG, Wang DZ, Pu WT.

Circ Res. 2014 Jul 18;115(3):354-63. doi: 10.1161/CIRCRESAHA.115.303632. Epub 2014 May 15.

2.

Hippo pathway effector Yap promotes cardiac regeneration.

Xin M, Kim Y, Sutherland LB, Murakami M, Qi X, McAnally J, Porrello ER, Mahmoud AI, Tan W, Shelton JM, Richardson JA, Sadek HA, Bassel-Duby R, Olson EN.

Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):13839-44. doi: 10.1073/pnas.1313192110. Epub 2013 Aug 5.

3.

Yes-associated protein isoform 1 (Yap1) promotes cardiomyocyte survival and growth to protect against myocardial ischemic injury.

Del Re DP, Yang Y, Nakano N, Cho J, Zhai P, Yamamoto T, Zhang N, Yabuta N, Nojima H, Pan D, Sadoshima J.

J Biol Chem. 2013 Feb 8;288(6):3977-88. doi: 10.1074/jbc.M112.436311. Epub 2012 Dec 30.

4.

miR-206 Mediates YAP-Induced Cardiac Hypertrophy and Survival.

Yang Y, Del Re DP, Nakano N, Sciarretta S, Zhai P, Park J, Sayed D, Shirakabe A, Matsushima S, Park Y, Tian B, Abdellatif M, Sadoshima J.

Circ Res. 2015 Oct 23;117(10):891-904. doi: 10.1161/CIRCRESAHA.115.306624. Epub 2015 Sep 2.

5.

Pi3kcb links Hippo-YAP and PI3K-AKT signaling pathways to promote cardiomyocyte proliferation and survival.

Lin Z, Zhou P, von Gise A, Gu F, Ma Q, Chen J, Guo H, van Gorp PR, Wang DZ, Pu WT.

Circ Res. 2015 Jan 2;116(1):35-45. doi: 10.1161/CIRCRESAHA.115.304457. Epub 2014 Sep 23.

6.

Alpha-catenins control cardiomyocyte proliferation by regulating Yap activity.

Li J, Gao E, Vite A, Yi R, Gomez L, Goossens S, van Roy F, Radice GL.

Circ Res. 2015 Jan 2;116(1):70-9. doi: 10.1161/CIRCRESAHA.116.304472. Epub 2014 Oct 10.

7.

Deletion of yes-associated protein (YAP) specifically in cardiac and vascular smooth muscle cells reveals a crucial role for YAP in mouse cardiovascular development.

Wang Y, Hu G, Liu F, Wang X, Wu M, Schwarz JJ, Zhou J.

Circ Res. 2014 Mar 14;114(6):957-65. doi: 10.1161/CIRCRESAHA.114.303411. Epub 2014 Jan 29.

8.

Regulation of insulin-like growth factor signaling by Yap governs cardiomyocyte proliferation and embryonic heart size.

Xin M, Kim Y, Sutherland LB, Qi X, McAnally J, Schwartz RJ, Richardson JA, Bassel-Duby R, Olson EN.

Sci Signal. 2011 Oct 25;4(196):ra70. doi: 10.1126/scisignal.2002278.

9.

Cardiomyocyte cell cycle activation improves cardiac function after myocardial infarction.

Hassink RJ, Pasumarthi KB, Nakajima H, Rubart M, Soonpaa MH, de la Rivière AB, Doevendans PA, Field LJ.

Cardiovasc Res. 2008 Apr 1;78(1):18-25. Epub 2007 Dec 12.

10.

Harnessing Hippo in the heart: Hippo/Yap signaling and applications to heart regeneration and rejuvenation.

Lin Z, Pu WT.

Stem Cell Res. 2014 Nov;13(3 Pt B):571-81. doi: 10.1016/j.scr.2014.04.010. Epub 2014 May 6. Review.

11.

Overexpression of Tbx20 in Adult Cardiomyocytes Promotes Proliferation and Improves Cardiac Function After Myocardial Infarction.

Xiang FL, Guo M, Yutzey KE.

Circulation. 2016 Mar 15;133(11):1081-92. doi: 10.1161/CIRCULATIONAHA.115.019357. Epub 2016 Feb 3.

12.

Hippo in the path to heart repair.

Papizan JB, Olson EN.

Circ Res. 2014 Jul 18;115(3):332-4. doi: 10.1161/CIRCRESAHA.114.304389. No abstract available.

13.

Cardiac-selective expression of extracellular superoxide dismutase after systemic injection of adeno-associated virus 9 protects the heart against post-myocardial infarction left ventricular remodeling.

Konkalmatt PR, Beyers RJ, O'Connor DM, Xu Y, Seaman ME, French BA.

Circ Cardiovasc Imaging. 2013 May 1;6(3):478-86. doi: 10.1161/CIRCIMAGING.112.000320. Epub 2013 Mar 27.

14.

S-Nitrosoglutathione Reductase Deficiency Enhances the Proliferative Expansion of Adult Heart Progenitors and Myocytes Post Myocardial Infarction.

Hatzistergos KE, Paulino EC, Dulce RA, Takeuchi LM, Bellio MA, Kulandavelu S, Cao Y, Balkan W, Kanashiro-Takeuchi RM, Hare JM.

J Am Heart Assoc. 2015 Jul 15;4(7). pii: e001974. doi: 10.1161/JAHA.115.001974.

15.

Pitx2 promotes heart repair by activating the antioxidant response after cardiac injury.

Tao G, Kahr PC, Morikawa Y, Zhang M, Rahmani M, Heallen TR, Li L, Sun Z, Olson EN, Amendt BA, Martin JF.

Nature. 2016 Jun 2;534(7605):119-23. doi: 10.1038/nature17959. Epub 2016 May 25.

16.

Cardiomyocyte-specific overexpression of human stem cell factor improves cardiac function and survival after myocardial infarction in mice.

Xiang FL, Lu X, Hammoud L, Zhu P, Chidiac P, Robbins J, Feng Q.

Circulation. 2009 Sep 22;120(12):1065-74, 9 p following 1074. doi: 10.1161/CIRCULATIONAHA.108.839068. Epub 2009 Sep 8.

17.

Cardiac AAV9-S100A1 gene therapy rescues post-ischemic heart failure in a preclinical large animal model.

Pleger ST, Shan C, Ksienzyk J, Bekeredjian R, Boekstegers P, Hinkel R, Schinkel S, Leuchs B, Ludwig J, Qiu G, Weber C, Raake P, Koch WJ, Katus HA, Müller OJ, Most P.

Sci Transl Med. 2011 Jul 20;3(92):92ra64. doi: 10.1126/scitranslmed.3002097.

18.

Regulation of Myocardial Cell Growth and Death by the Hippo Pathway.

Ikeda S, Sadoshima J.

Circ J. 2016 Jun 24;80(7):1511-9. doi: 10.1253/circj.CJ-16-0476. Epub 2016 Jun 10. Review.

19.

Nerve growth factor promotes cardiac repair following myocardial infarction.

Meloni M, Caporali A, Graiani G, Lagrasta C, Katare R, Van Linthout S, Spillmann F, Campesi I, Madeddu P, Quaini F, Emanueli C.

Circ Res. 2010 Apr 16;106(7):1275-84. doi: 10.1161/CIRCRESAHA.109.210088. Epub 2010 Apr 1.

20.

Hippo pathway inhibits Wnt signaling to restrain cardiomyocyte proliferation and heart size.

Heallen T, Zhang M, Wang J, Bonilla-Claudio M, Klysik E, Johnson RL, Martin JF.

Science. 2011 Apr 22;332(6028):458-61. doi: 10.1126/science.1199010.

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