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Items: 1 to 20 of 100

1.

Overexpression of far upstream element (FUSE) binding protein (FBP)-interacting repressor (FIR) supports growth of hepatocellular carcinoma.

Malz M, Bovet M, Samarin J, Rabenhorst U, Sticht C, Bissinger M, Roessler S, Bermejo JL, Renner M, Calvisi DF, Singer S, Ganzinger M, Weber A, Gretz N, Zörnig M, Schirmacher P, Breuhahn K.

Hepatology. 2014 Oct;60(4):1241-50. doi: 10.1002/hep.27218. Epub 2014 Jul 31.

PMID:
24824848
2.

Concomitant expression of far upstream element (FUSE) binding protein (FBP) interacting repressor (FIR) and its splice variants induce migration and invasion of non-small cell lung cancer (NSCLC) cells.

Müller B, Bovet M, Yin Y, Stichel D, Malz M, González-Vallinas M, Middleton A, Ehemann V, Schmitt J, Muley T, Meister M, Herpel E, Singer S, Warth A, Schirmacher P, Drasdo D, Matthäus F, Breuhahn K.

J Pathol. 2015 Nov;237(3):390-401. doi: 10.1002/path.4588. Epub 2015 Sep 8.

PMID:
26177862
3.

Alternative splicing of FBP-interacting repressor coordinates c-Myc, P27Kip1/cyclinE and Ku86/XRCC5 expression as a molecular sensor for bleomycin-induced DNA damage pathway.

Rahmutulla B, Matsushita K, Satoh M, Seimiya M, Tsuchida S, Kubo S, Shimada H, Ohtsuka M, Miyazaki M, Nomura F.

Oncotarget. 2014 May 15;5(9):2404-17.

4.

Overexpression of far upstream element binding proteins: a mechanism regulating proliferation and migration in liver cancer cells.

Malz M, Weber A, Singer S, Riehmer V, Bissinger M, Riener MO, Longerich T, Soll C, Vogel A, Angel P, Schirmacher P, Breuhahn K.

Hepatology. 2009 Oct;50(4):1130-9. doi: 10.1002/hep.23051.

PMID:
19585652
5.

Non-transmissible Sendai virus vector encoding c-myc suppressor FBP-interacting repressor for cancer therapy.

Matsushita K, Shimada H, Ueda Y, Inoue M, Hasegawa M, Tomonaga T, Matsubara H, Nomura F.

World J Gastroenterol. 2014 Apr 21;20(15):4316-28. doi: 10.3748/wjg.v20.i15.4316.

6.

SAP155-mediated c-myc suppressor far-upstream element-binding protein-interacting repressor splicing variants are activated in colon cancer tissues.

Kajiwara T, Matsushita K, Itoga S, Tamura M, Tanaka N, Tomonaga T, Matsubara H, Shimada H, Habara Y, Matsuo M, Nomura F.

Cancer Sci. 2013 Feb;104(2):149-56. doi: 10.1111/cas.12058. Epub 2012 Dec 4.

7.

Quantitative characterization of the interactions among c-myc transcriptional regulators FUSE, FBP, and FIR.

Hsiao HH, Nath A, Lin CY, Folta-Stogniew EJ, Rhoades E, Braddock DT.

Biochemistry. 2010 Jun 8;49(22):4620-34. doi: 10.1021/bi9021445.

PMID:
20420426
8.

Interactions between SAP155 and FUSE-binding protein-interacting repressor bridges c-Myc and P27Kip1 expression.

Matsushita K, Tamura M, Tanaka N, Tomonaga T, Matsubara H, Shimada H, Levens D, He L, Liu J, Yoshida M, Nomura F.

Mol Cancer Res. 2013 Jul;11(7):689-98. doi: 10.1158/1541-7786.MCR-12-0673. Epub 2013 Apr 17.

9.

Nuclear expression of the ubiquitin ligase seven in absentia homolog (SIAH)-1 induces proliferation and migration of liver cancer cells.

Brauckhoff A, Malz M, Tschaharganeh D, Malek N, Weber A, Riener MO, Soll C, Samarin J, Bissinger M, Schmidt J, Longerich T, Ehemann V, Schirmacher P, Breuhahn K.

J Hepatol. 2011 Nov;55(5):1049-57. doi: 10.1016/j.jhep.2011.02.019. Epub 2011 Feb 26.

PMID:
21356256
10.

Haploinsufficiency of the c-myc transcriptional repressor FIR, as a dominant negative-alternative splicing model, promoted p53-dependent T-cell acute lymphoblastic leukemia progression by activating Notch1.

Matsushita K, Kitamura K, Rahmutulla B, Tanaka N, Ishige T, Satoh M, Hoshino T, Miyagi S, Mori T, Itoga S, Shimada H, Tomonaga T, Kito M, Nakajima-Takagi Y, Kubo S, Nakaseko C, Hatano M, Miki T, Matsuo M, Fukuyo M, Kaneda A, Iwama A, Nomura F.

Oncotarget. 2015 Mar 10;6(7):5102-17.

11.

SAP155-mediated splicing of FUSE-binding protein-interacting repressor serves as a molecular switch for c-myc gene expression.

Matsushita K, Kajiwara T, Tamura M, Satoh M, Tanaka N, Tomonaga T, Matsubara H, Shimada H, Yoshimoto R, Ito A, Kubo S, Natsume T, Levens D, Yoshida M, Nomura F.

Mol Cancer Res. 2012 Jun;10(6):787-99. doi: 10.1158/1541-7786.MCR-11-0462. Epub 2012 Apr 11.

12.

PI3K/AKT/mTOR-dependent stabilization of oncogenic far-upstream element binding proteins in hepatocellular carcinoma cells.

Samarin J, Laketa V, Malz M, Roessler S, Stein I, Horwitz E, Singer S, Dimou E, Cigliano A, Bissinger M, Falk CS, Chen X, Dooley S, Pikarsky E, Calvisi DF, Schultz C, Schirmacher P, Breuhahn K.

Hepatology. 2016 Mar;63(3):813-26. doi: 10.1002/hep.28357. Epub 2016 Jan 14.

13.

The FBP interacting repressor targets TFIIH to inhibit activated transcription.

Liu J, He L, Collins I, Ge H, Libutti D, Li J, Egly JM, Levens D.

Mol Cell. 2000 Feb;5(2):331-41.

14.

Molecular basis of FIR-mediated c-myc transcriptional control.

Cukier CD, Hollingworth D, Martin SR, Kelly G, Díaz-Moreno I, Ramos A.

Nat Struct Mol Biol. 2010 Sep;17(9):1058-64. doi: 10.1038/nsmb.1883. Epub 2010 Aug 15.

15.

Argonaute2 promotes tumor metastasis by way of up-regulating focal adhesion kinase expression in hepatocellular carcinoma.

Cheng N, Li Y, Han ZG.

Hepatology. 2013 May;57(5):1906-18. doi: 10.1002/hep.26202.

PMID:
23258480
16.

The E2F transcription factor 1 transactives stathmin 1 in hepatocellular carcinoma.

Chen YL, Uen YH, Li CF, Horng KC, Chen LR, Wu WR, Tseng HY, Huang HY, Wu LC, Shiue YL.

Ann Surg Oncol. 2013 Nov;20(12):4041-54. doi: 10.1245/s10434-012-2519-8. Epub 2012 Aug 22.

PMID:
22911364
17.

The FUSE/FBP/FIR/TFIIH system is a molecular machine programming a pulse of c-myc expression.

Liu J, Kouzine F, Nie Z, Chung HJ, Elisha-Feil Z, Weber A, Zhao K, Levens D.

EMBO J. 2006 May 17;25(10):2119-30. Epub 2006 Apr 20.

18.

[Alternative Splicing Detection as Biomarker Candidates for Cancer Diagnosis and Treatment with Establishment of Clinical Biobank in Chiba University].

Matsushita K, Itoga S, Nishimura M, Furuta K, Nomura F.

Rinsho Byori. 2015 Mar;63(3):347-60. Review. Japanese.

PMID:
26524858
19.

Adenovirus-mediated FIR demonstrated TP53-independent cell-killing effect and enhanced antitumor activity of carbon-ion beams.

Kano M, Matsushita K, Rahmutulla B, Yamada S, Shimada H, Kubo S, Hiwasa T, Matsubara H, Nomura F.

Gene Ther. 2016 Jan;23(1):50-6. doi: 10.1038/gt.2015.84. Epub 2015 Aug 4.

PMID:
26241176
20.

Overexpression of the far upstream element binding protein 1 in hepatocellular carcinoma is required for tumor growth.

Rabenhorst U, Beinoraviciute-Kellner R, Brezniceanu ML, Joos S, Devens F, Lichter P, Rieker RJ, Trojan J, Chung HJ, Levens DL, Zörnig M.

Hepatology. 2009 Oct;50(4):1121-9. doi: 10.1002/hep.23098.

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