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Items: 1 to 20 of 111

1.

A novel Aβ-fibrinogen interaction inhibitor rescues altered thrombosis and cognitive decline in Alzheimer's disease mice.

Ahn HJ, Glickman JF, Poon KL, Zamolodchikov D, Jno-Charles OC, Norris EH, Strickland S.

J Exp Med. 2014 Jun 2;211(6):1049-62. doi: 10.1084/jem.20131751. Epub 2014 May 12.

2.

Alzheimer's disease: Aβ-fibrinogen interaction inhibitor improves cognition in AD.

Flemming A.

Nat Rev Drug Discov. 2014 Jul;13(7):494. doi: 10.1038/nrd4370. Epub 2014 Jun 20. No abstract available.

PMID:
24948119
3.

Fibrinogen and beta-amyloid association alters thrombosis and fibrinolysis: a possible contributing factor to Alzheimer's disease.

Cortes-Canteli M, Paul J, Norris EH, Bronstein R, Ahn HJ, Zamolodchikov D, Bhuvanendran S, Fenz KM, Strickland S.

Neuron. 2010 Jun 10;66(5):695-709. doi: 10.1016/j.neuron.2010.05.014.

4.

S14G-humanin improves cognitive deficits and reduces amyloid pathology in the middle-aged APPswe/PS1dE9 mice.

Zhang W, Zhang W, Li Z, Hao J, Zhang Z, Liu L, Mao N, Miao J, Zhang L.

Pharmacol Biochem Behav. 2012 Jan;100(3):361-9. doi: 10.1016/j.pbb.2011.09.012. Epub 2011 Oct 2.

PMID:
21993310
5.

Alzheimer's disease peptide beta-amyloid interacts with fibrinogen and induces its oligomerization.

Ahn HJ, Zamolodchikov D, Cortes-Canteli M, Norris EH, Glickman JF, Strickland S.

Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21812-7. doi: 10.1073/pnas.1010373107. Epub 2010 Nov 22.

6.

Nobiletin, a citrus flavonoid, improves cognitive impairment and reduces soluble Aβ levels in a triple transgenic mouse model of Alzheimer's disease (3XTg-AD).

Nakajima A, Aoyama Y, Shin EJ, Nam Y, Kim HC, Nagai T, Yokosuka A, Mimaki Y, Yokoi T, Ohizumi Y, Yamada K.

Behav Brain Res. 2015 Aug 1;289:69-77. doi: 10.1016/j.bbr.2015.04.028. Epub 2015 Apr 22.

PMID:
25913833
7.

Caffeine suppresses amyloid-beta levels in plasma and brain of Alzheimer's disease transgenic mice.

Cao C, Cirrito JR, Lin X, Wang L, Verges DK, Dickson A, Mamcarz M, Zhang C, Mori T, Arendash GW, Holtzman DM, Potter H.

J Alzheimers Dis. 2009;17(3):681-97. doi: 10.3233/JAD-2009-1071. Erratum in: J Alzheimers Dis. 2009 Nov;18(3):727. Wang, Lilly [corrected to Wang, Li]..

8.
9.

Transthyretin stabilization by iododiflunisal promotes amyloid-β peptide clearance, decreases its deposition, and ameliorates cognitive deficits in an Alzheimer's disease mouse model.

Ribeiro CA, Oliveira SM, Guido LF, Magalhães A, Valencia G, Arsequell G, Saraiva MJ, Cardoso I.

J Alzheimers Dis. 2014;39(2):357-70. doi: 10.3233/JAD-131355.

PMID:
24169237
10.

Soluble Aβ levels correlate with cognitive deficits in the 12-month-old APPswe/PS1dE9 mouse model of Alzheimer's disease.

Zhang W, Hao J, Liu R, Zhang Z, Lei G, Su C, Miao J, Li Z.

Behav Brain Res. 2011 Sep 23;222(2):342-50. doi: 10.1016/j.bbr.2011.03.072. Epub 2011 Apr 14.

PMID:
21513747
11.

Self-assembling nanofibers alter the processing of amyloid precursor protein in a transgenic mouse model of Alzheimer's disease.

Yang H, Yang H, Xie Z, Wang P, Bi J.

Neurol Res. 2015 Jan;37(1):84-91. doi: 10.1179/1743132814Y.0000000417. Epub 2014 Jul 9.

PMID:
25005263
12.

Fibrinogen and altered hemostasis in Alzheimer's disease.

Cortes-Canteli M, Zamolodchikov D, Ahn HJ, Strickland S, Norris EH.

J Alzheimers Dis. 2012;32(3):599-608. doi: 10.3233/JAD-2012-120820. Review.

13.

Pyruvate prevents the development of age-dependent cognitive deficits in a mouse model of Alzheimer's disease without reducing amyloid and tau pathology.

Isopi E, Granzotto A, Corona C, Bomba M, Ciavardelli D, Curcio M, Canzoniero LM, Navarra R, Lattanzio R, Piantelli M, Sensi SL.

Neurobiol Dis. 2015 Sep;81:214-24. doi: 10.1016/j.nbd.2014.11.013. Epub 2014 Nov 28.

PMID:
25434488
14.

Gintonin, a ginseng-derived lysophosphatidic acid receptor ligand, attenuates Alzheimer's disease-related neuropathies: involvement of non-amyloidogenic processing.

Hwang SH, Shin EJ, Shin TJ, Lee BH, Choi SH, Kang J, Kim HJ, Kwon SH, Jang CG, Lee JH, Kim HC, Nah SY.

J Alzheimers Dis. 2012;31(1):207-23. doi: 10.3233/JAD-2012-120439.

PMID:
22543851
15.

Protection against cognitive deficits and markers of neurodegeneration by long-term oral administration of melatonin in a transgenic model of Alzheimer disease.

Olcese JM, Cao C, Mori T, Mamcarz MB, Maxwell A, Runfeldt MJ, Wang L, Zhang C, Lin X, Zhang G, Arendash GW.

J Pineal Res. 2009 Aug;47(1):82-96. doi: 10.1111/j.1600-079X.2009.00692.x. Epub 2009 Jun 17.

PMID:
19538338
16.

Tripchlorolide improves cognitive deficits by reducing amyloid β and upregulating synapse-related proteins in a transgenic model of Alzheimer's Disease.

Zeng Y, Zhang J, Zhu Y, Zhang J, Shen H, Lu J, Pan X, Lin N, Dai X, Zhou M, Chen X.

J Neurochem. 2015 Apr;133(1):38-52. doi: 10.1111/jnc.13056. Epub 2015 Mar 8.

17.

Lifelong immunization with human beta-amyloid (1-42) protects Alzheimer's transgenic mice against cognitive impairment throughout aging.

Jensen MT, Mottin MD, Cracchiolo JR, Leighty RE, Arendash GW.

Neuroscience. 2005;130(3):667-84.

PMID:
15590151
18.

Loss of muscarinic M1 receptor exacerbates Alzheimer's disease-like pathology and cognitive decline.

Medeiros R, Kitazawa M, Caccamo A, Baglietto-Vargas D, Estrada-Hernandez T, Cribbs DH, Fisher A, LaFerla FM.

Am J Pathol. 2011 Aug;179(2):980-91. doi: 10.1016/j.ajpath.2011.04.041. Epub 2011 Jun 23.

19.

Mitochondrial amyloid-beta levels are associated with the extent of mitochondrial dysfunction in different brain regions and the degree of cognitive impairment in Alzheimer's transgenic mice.

Dragicevic N, Mamcarz M, Zhu Y, Buzzeo R, Tan J, Arendash GW, Bradshaw PC.

J Alzheimers Dis. 2010;20 Suppl 2:S535-50. doi: 10.3233/JAD-2010-100342.

PMID:
20463404
20.

Elevation of brain magnesium prevents and reverses cognitive deficits and synaptic loss in Alzheimer's disease mouse model.

Li W, Yu J, Liu Y, Huang X, Abumaria N, Zhu Y, Huang X, Xiong W, Ren C, Liu XG, Chui D, Liu G.

J Neurosci. 2013 May 8;33(19):8423-41. doi: 10.1523/JNEUROSCI.4610-12.2013. Retraction in: J Neurosci. 2014 Apr 16;34(16):5733.

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