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The role of H1 linker histone subtypes in preserving the fidelity of elaboration of mesendodermal and neuroectodermal lineages during embryonic development.

Nguyen GD, Gokhan S, Molero AE, Yang SM, Kim BJ, Skoultchi AI, Mehler MF.

PLoS One. 2014 May 6;9(5):e96858. doi: 10.1371/journal.pone.0096858.


Histone h1 depletion impairs embryonic stem cell differentiation.

Zhang Y, Cooke M, Panjwani S, Cao K, Krauth B, Ho PY, Medrzycki M, Berhe DT, Pan C, McDevitt TC, Fan Y.

PLoS Genet. 2012;8(5):e1002691. doi: 10.1371/journal.pgen.1002691.


Reduction of Hox gene expression by histone H1 depletion.

Zhang Y, Liu Z, Medrzycki M, Cao K, Fan Y.

PLoS One. 2012;7(6):e38829. doi: 10.1371/journal.pone.0038829.


Functions of huntingtin in germ layer specification and organogenesis.

Nguyen GD, Molero AE, Gokhan S, Mehler MF.

PLoS One. 2013 Aug 13;8(8):e72698. doi: 10.1371/journal.pone.0072698. Erratum in: PLoS One. 2013;8(9). doi:10.1371/annotation/edee8dfa-6b2a-44f4-866a-098f186e27f0.


Insulin redirects differentiation from cardiogenic mesoderm and endoderm to neuroectoderm in differentiating human embryonic stem cells.

Freund C, Ward-van Oostwaard D, Monshouwer-Kloots J, van den Brink S, van Rooijen M, Xu X, Zweigerdt R, Mummery C, Passier R.

Stem Cells. 2008 Mar;26(3):724-33.


SIP1 mediates cell-fate decisions between neuroectoderm and mesendoderm in human pluripotent stem cells.

Chng Z, Teo A, Pedersen RA, Vallier L.

Cell Stem Cell. 2010 Jan 8;6(1):59-70. doi: 10.1016/j.stem.2009.11.015.


Rotary suspension culture enhances mesendoderm differentiation of embryonic stem cells through modulation of Wnt/β-catenin pathway.

Lei X, Deng Z, Zhang H, Zhao H, Zhou J, Liu S, Chen Q, Ning L, Cao Y, Wang X, Zhang X, Duan E.

Stem Cell Rev. 2014 Aug;10(4):526-38. doi: 10.1007/s12015-014-9511-6.


High-resolution mapping of h1 linker histone variants in embryonic stem cells.

Cao K, Lailler N, Zhang Y, Kumar A, Uppal K, Liu Z, Lee EK, Wu H, Medrzycki M, Pan C, Ho PY, Cooper GP Jr, Dong X, Bock C, Bouhassira EE, Fan Y.

PLoS Genet. 2013;9(4):e1003417. doi: 10.1371/journal.pgen.1003417.


Selective roles of normal and mutant huntingtin in neural induction and early neurogenesis.

Nguyen GD, Gokhan S, Molero AE, Mehler MF.

PLoS One. 2013 May 14;8(5):e64368. doi: 10.1371/journal.pone.0064368.


Propensity of human embryonic stem cell lines during early stage of lineage specification controls their terminal differentiation into mature cell types.

Pal R, Totey S, Mamidi MK, Bhat VS, Totey S.

Exp Biol Med (Maywood). 2009 Oct;234(10):1230-43. doi: 10.3181/0901-RM-38.


Major amino acids in collagen hydrolysate regulate the differentiation of mouse embryoid bodies.

Date Y, Hasegawa S, Yamada T, Inoue Y, Mizutani H, Nakata S, Akamatsu H.

J Biosci Bioeng. 2013 Sep;116(3):386-90. doi: 10.1016/j.jbiosc.2013.03.014.


Mll2 controls cardiac lineage differentiation of mouse embryonic stem cells by promoting H3K4me3 deposition at cardiac-specific genes.

Wan X, Liu L, Ding X, Zhou P, Yuan X, Zhou Z, Hu P, Zhou H, Li Q, Zhang S, Xiong S, Zhang Y.

Stem Cell Rev. 2014 Oct;10(5):643-52. doi: 10.1007/s12015-014-9527-y.


Differentiation of mouse embryonic stem cells into endoderm without embryoid body formation.

Kim PT, Hoffman BG, Plesner A, Helgason CD, Verchere CB, Chung SW, Warnock GL, Mui AL, Ong CJ.

PLoS One. 2010 Nov 30;5(11):e14146. doi: 10.1371/journal.pone.0014146.


Enforced expression of Mixl1 during mouse ES cell differentiation suppresses hematopoietic mesoderm and promotes endoderm formation.

Lim SM, Pereira L, Wong MS, Hirst CE, Van Vranken BE, Pick M, Trounson A, Elefanty AG, Stanley EG.

Stem Cells. 2009 Feb;27(2):363-74. doi: 10.1634/stemcells.2008-1008.


Suv4-20h histone methyltransferases promote neuroectodermal differentiation by silencing the pluripotency-associated Oct-25 gene.

Nicetto D, Hahn M, Jung J, Schneider TD, Straub T, David R, Schotta G, Rupp RA.

PLoS Genet. 2013;9(1):e1003188. doi: 10.1371/journal.pgen.1003188.


Histone variants as emerging regulators of embryonic stem cell identity.

Turinetto V, Giachino C.

Epigenetics. 2015;10(7):563-73. doi: 10.1080/15592294.2015.1053682. Review.


Single cell analysis facilitates staging of Blimp1-dependent primordial germ cells derived from mouse embryonic stem cells.

Vincent JJ, Li Z, Lee SA, Liu X, Etter MO, Diaz-Perez SV, Taylor SK, Gkountela S, Lindgren AG, Clark AT.

PLoS One. 2011;6(12):e28960. doi: 10.1371/journal.pone.0028960.


Downregulation of H19 improves the differentiation potential of mouse parthenogenetic embryonic stem cells.

Ragina NP, Schlosser K, Knott JG, Senagore PK, Swiatek PJ, Chang EA, Fakhouri WD, Schutte BC, Kiupel M, Cibelli JB.

Stem Cells Dev. 2012 May 1;21(7):1134-44. doi: 10.1089/scd.2011.0152.


Wnt signaling mediates self-organization and axis formation in embryoid bodies.

ten Berge D, Koole W, Fuerer C, Fish M, Eroglu E, Nusse R.

Cell Stem Cell. 2008 Nov 6;3(5):508-18. doi: 10.1016/j.stem.2008.09.013.


Temporal modulation of β-catenin signaling by multicellular aggregation kinetics impacts embryonic stem cell cardiomyogenesis.

Kinney MA, Sargent CY, McDevitt TC.

Stem Cells Dev. 2013 Oct 1;22(19):2665-77. doi: 10.1089/scd.2013.0007.

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