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Items: 1 to 20 of 128

1.

GPR179 is required for high sensitivity of the mGluR6 signaling cascade in depolarizing bipolar cells.

Ray TA, Heath KM, Hasan N, Noel JM, Samuels IS, Martemyanov KA, Peachey NS, McCall MA, Gregg RG.

J Neurosci. 2014 Apr 30;34(18):6334-43. doi: 10.1523/JNEUROSCI.4044-13.2014.

2.

LRIT3 is essential to localize TRPM1 to the dendritic tips of depolarizing bipolar cells and may play a role in cone synapse formation.

Neuillé M, Morgans CW, Cao Y, Orhan E, Michiels C, Sahel JA, Audo I, Duvoisin RM, Martemyanov KA, Zeitz C.

Eur J Neurosci. 2015 Aug;42(3):1966-75. doi: 10.1111/ejn.12959.

3.

Intermolecular Interaction between Anchoring Subunits Specify Subcellular Targeting and Function of RGS Proteins in Retina ON-Bipolar Neurons.

Sarria I, Orlandi C, McCall MA, Gregg RG, Martemyanov KA.

J Neurosci. 2016 Mar 9;36(10):2915-25. doi: 10.1523/JNEUROSCI.3833-15.2016.

4.

Two R7 regulator of G-protein signaling proteins shape retinal bipolar cell signaling.

Mojumder DK, Qian Y, Wensel TG.

J Neurosci. 2009 Jun 17;29(24):7753-65. doi: 10.1523/JNEUROSCI.1794-09.2009.

5.

RGS7 and -11 complexes accelerate the ON-bipolar cell light response.

Zhang J, Jeffrey BG, Morgans CW, Burke NS, Haley TL, Duvoisin RM, Brown RL.

Invest Ophthalmol Vis Sci. 2010 Feb;51(2):1121-9. doi: 10.1167/iovs.09-4163.

6.

Orphan receptor GPR179 forms macromolecular complexes with components of metabotropic signaling cascade in retina ON-bipolar neurons.

Orlandi C, Cao Y, Martemyanov KA.

Invest Ophthalmol Vis Sci. 2013 Oct 29;54(10):7153-61. doi: 10.1167/iovs.13-12907.

7.

G-protein-mediated inhibition of the Trp channel TRPM1 requires the Gβγ dimer.

Shen Y, Rampino MA, Carroll RC, Nawy S.

Proc Natl Acad Sci U S A. 2012 May 29;109(22):8752-7. doi: 10.1073/pnas.1117433109.

8.

Gbeta5-RGS complexes co-localize with mGluR6 in retinal ON-bipolar cells.

Morgans CW; Weiwei Liu., Wensel TG, Brown RL, Perez-Leon JA, Bearnot B, Duvoisin RM.

Eur J Neurosci. 2007 Nov;26(10):2899-905.

9.

GPR179 is required for depolarizing bipolar cell function and is mutated in autosomal-recessive complete congenital stationary night blindness.

Peachey NS, Ray TA, Florijn R, Rowe LB, Sjoerdsma T, Contreras-Alcantara S, Baba K, Tosini G, Pozdeyev N, Iuvone PM, Bojang P Jr, Pearring JN, Simonsz HJ, van Genderen M, Birch DG, Traboulsi EI, Dorfman A, Lopez I, Ren H, Goldberg AF, Nishina PM, Lachapelle P, McCall MA, Koenekoop RK, Bergen AA, Kamermans M, Gregg RG.

Am J Hum Genet. 2012 Feb 10;90(2):331-9. doi: 10.1016/j.ajhg.2011.12.006.

10.

mGluR6 deletion renders the TRPM1 channel in retina inactive.

Xu Y, Dhingra A, Fina ME, Koike C, Furukawa T, Vardi N.

J Neurophysiol. 2012 Feb;107(3):948-57. doi: 10.1152/jn.00933.2011.

11.

Presence of the Gpr179(nob5) allele in a C3H-derived transgenic mouse.

Balmer J, Ji R, Ray TA, Selber F, Gassmann M, Peachey NS, Gregg RG, Enzmann V.

Mol Vis. 2013 Dec 31;19:2615-25.

12.

TRPM1 is a component of the retinal ON bipolar cell transduction channel in the mGluR6 cascade.

Koike C, Obara T, Uriu Y, Numata T, Sanuki R, Miyata K, Koyasu T, Ueno S, Funabiki K, Tani A, Ueda H, Kondo M, Mori Y, Tachibana M, Furukawa T.

Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):332-7. doi: 10.1073/pnas.0912730107.

13.

Defective retinal depolarizing bipolar cells in regulators of G protein signaling (RGS) 7 and 11 double null mice.

Shim H, Wang CT, Chen YL, Chau VQ, Fu KG, Yang J, McQuiston AR, Fisher RA, Chen CK.

J Biol Chem. 2012 Apr 27;287(18):14873-9. doi: 10.1074/jbc.M112.345751.

14.

A transient receptor potential-like channel mediates synaptic transmission in rod bipolar cells.

Shen Y, Heimel JA, Kamermans M, Peachey NS, Gregg RG, Nawy S.

J Neurosci. 2009 May 13;29(19):6088-93. doi: 10.1523/JNEUROSCI.0132-09.2009.

15.

TRPM1 is required for the depolarizing light response in retinal ON-bipolar cells.

Morgans CW, Zhang J, Jeffrey BG, Nelson SM, Burke NS, Duvoisin RM, Brown RL.

Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):19174-8. doi: 10.1073/pnas.0908711106.

16.

Localization of Cacna1s to ON bipolar dendritic tips requires mGluR6-related cascade elements.

Tummala SR, Neinstein A, Fina ME, Dhingra A, Vardi N.

Invest Ophthalmol Vis Sci. 2014 Mar 10;55(3):1483-92. doi: 10.1167/iovs.13-13766.

17.

Regulators of G protein signaling RGS7 and RGS11 determine the onset of the light response in ON bipolar neurons.

Cao Y, Pahlberg J, Sarria I, Kamasawa N, Sampath AP, Martemyanov KA.

Proc Natl Acad Sci U S A. 2012 May 15;109(20):7905-10. doi: 10.1073/pnas.1202332109.

18.

Synaptic pathology and therapeutic repair in adult retinoschisis mouse by AAV-RS1 transfer.

Ou J, Vijayasarathy C, Ziccardi L, Chen S, Zeng Y, Marangoni D, Pope JG, Bush RA, Wu Z, Li W, Sieving PA.

J Clin Invest. 2015 Jul 1;125(7):2891-903. doi: 10.1172/JCI81380.

19.

A role for nyctalopin, a small leucine-rich repeat protein, in localizing the TRP melastatin 1 channel to retinal depolarizing bipolar cell dendrites.

Pearring JN, Bojang P Jr, Shen Y, Koike C, Furukawa T, Nawy S, Gregg RG.

J Neurosci. 2011 Jul 6;31(27):10060-6. doi: 10.1523/JNEUROSCI.1014-11.2011.

20.

Gβ3 is required for normal light ON responses and synaptic maintenance.

Dhingra A, Ramakrishnan H, Neinstein A, Fina ME, Xu Y, Li J, Chung DC, Lyubarsky A, Vardi N.

J Neurosci. 2012 Aug 15;32(33):11343-55. doi: 10.1523/JNEUROSCI.1436-12.2012.

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