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Items: 1 to 20 of 109

1.

An integrative analysis of colon cancer identifies an essential function for PRPF6 in tumor growth.

Adler AS, McCleland ML, Yee S, Yaylaoglu M, Hussain S, Cosino E, Quinones G, Modrusan Z, Seshagiri S, Torres E, Chopra VS, Haley B, Zhang Z, Blackwood EM, Singh M, Junttila M, Stephan JP, Liu J, Pau G, Fearon ER, Jiang Z, Firestein R.

Genes Dev. 2014 May 15;28(10):1068-84. doi: 10.1101/gad.237206.113. Epub 2014 May 1.

2.

A missense mutation in PRPF6 causes impairment of pre-mRNA splicing and autosomal-dominant retinitis pigmentosa.

Tanackovic G, Ransijn A, Ayuso C, Harper S, Berson EL, Rivolta C.

Am J Hum Genet. 2011 May 13;88(5):643-9. doi: 10.1016/j.ajhg.2011.04.008. Epub 2011 May 5.

3.

SMNrp is an essential pre-mRNA splicing factor required for the formation of the mature spliceosome.

Meister G, Hannus S, Plöttner O, Baars T, Hartmann E, Fakan S, Laggerbauer B, Fischer U.

EMBO J. 2001 May 1;20(9):2304-14.

4.

SPF30 is an essential human splicing factor required for assembly of the U4/U5/U6 tri-small nuclear ribonucleoprotein into the spliceosome.

Rappsilber J, Ajuh P, Lamond AI, Mann M.

J Biol Chem. 2001 Aug 17;276(33):31142-50. Epub 2001 Apr 30.

5.

The splicing factor Prp17 interacts with the U2, U5 and U6 snRNPs and associates with the spliceosome pre- and post-catalysis.

Sapra AK, Khandelia P, Vijayraghavan U.

Biochem J. 2008 Dec 15;416(3):365-74. doi: 10.1042/BJ20081195.

PMID:
18691155
6.

Stable tri-snRNP integration is accompanied by a major structural rearrangement of the spliceosome that is dependent on Prp8 interaction with the 5' splice site.

Boesler C, Rigo N, Agafonov DE, Kastner B, Urlaub H, Will CL, Lührmann R.

RNA. 2015 Nov;21(11):1993-2005. doi: 10.1261/rna.053991.115. Epub 2015 Sep 18.

7.

Human PRP4 kinase is required for stable tri-snRNP association during spliceosomal B complex formation.

Schneider M, Hsiao HH, Will CL, Giet R, Urlaub H, Lührmann R.

Nat Struct Mol Biol. 2010 Feb;17(2):216-21. doi: 10.1038/nsmb.1718. Epub 2010 Jan 31.

PMID:
20118938
8.

Splicing factor SPF30 bridges an interaction between the prespliceosome protein U2AF35 and tri-small nuclear ribonucleoprotein protein hPrp3.

Little JT, Jurica MS.

J Biol Chem. 2008 Mar 28;283(13):8145-52. doi: 10.1074/jbc.M707984200. Epub 2008 Jan 22.

9.

The nuclear cap-binding complex interacts with the U4/U6·U5 tri-snRNP and promotes spliceosome assembly in mammalian cells.

Pabis M, Neufeld N, Steiner MC, Bojic T, Shav-Tal Y, Neugebauer KM.

RNA. 2013 Aug;19(8):1054-63. doi: 10.1261/rna.037069.112. Epub 2013 Jun 21.

10.
11.

Mammalian splicing factor SF1 interacts with SURP domains of U2 snRNP-associated proteins.

Crisci A, Raleff F, Bagdiul I, Raabe M, Urlaub H, Rain JC, Krämer A.

Nucleic Acids Res. 2015 Dec 2;43(21):10456-73. doi: 10.1093/nar/gkv952. Epub 2015 Sep 29.

12.

A split luciferase-based reporter for detection of a cellular macromolecular complex.

Maita H, Tomita K, Ariga H.

Anal Biochem. 2014 May 1;452:1-9. doi: 10.1016/j.ab.2014.01.015. Epub 2014 Feb 3.

PMID:
24503441
13.

Stem-loop 4 of U1 snRNA is essential for splicing and interacts with the U2 snRNP-specific SF3A1 protein during spliceosome assembly.

Sharma S, Wongpalee SP, Vashisht A, Wohlschlegel JA, Black DL.

Genes Dev. 2014 Nov 15;28(22):2518-31. doi: 10.1101/gad.248625.114.

14.

Regulation of constitutive and alternative mRNA splicing across the human transcriptome by PRPF8 is determined by 5' splice site strength.

Wickramasinghe VO, Gonzàlez-Porta M, Perera D, Bartolozzi AR, Sibley CR, Hallegger M, Ule J, Marioni JC, Venkitaraman AR.

Genome Biol. 2015 Sep 21;16:201. doi: 10.1186/s13059-015-0749-3.

15.

Interactions between SAP155 and FUSE-binding protein-interacting repressor bridges c-Myc and P27Kip1 expression.

Matsushita K, Tamura M, Tanaka N, Tomonaga T, Matsubara H, Shimada H, Levens D, He L, Liu J, Yoshida M, Nomura F.

Mol Cancer Res. 2013 Jul;11(7):689-98. doi: 10.1158/1541-7786.MCR-12-0673. Epub 2013 Apr 17.

16.

A novel yeast U2 snRNP protein, Snu17p, is required for the first catalytic step of splicing and for progression of spliceosome assembly.

Gottschalk A, Bartels C, Neubauer G, Lührmann R, Fabrizio P.

Mol Cell Biol. 2001 May;21(9):3037-46.

18.

Alternative splicing: aberrant splicing promotes colon tumour growth.

Lokody I.

Nat Rev Cancer. 2014 Jun;14(6):382-3. doi: 10.1038/nrc3753. No abstract available.

PMID:
24854075
19.

The large N-terminal region of the Brr2 RNA helicase guides productive spliceosome activation.

Absmeier E, Wollenhaupt J, Mozaffari-Jovin S, Becke C, Lee CT, Preussner M, Heyd F, Urlaub H, Lührmann R, Santos KF, Wahl MC.

Genes Dev. 2015 Dec 15;29(24):2576-87. doi: 10.1101/gad.271528.115. Epub 2015 Dec 4.

20.

A homolog of splicing factor SF1 is essential for development and is involved in the alternative splicing of pre-mRNA in Arabidopsis thaliana.

Jang YH, Park HY, Lee KC, Thu MP, Kim SK, Suh MC, Kang H, Kim JK.

Plant J. 2014 May;78(4):591-603. doi: 10.1111/tpj.12491. Epub 2014 Apr 23.

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