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Myocardial perfusion and oxygenation are impaired during stress in severe aortic stenosis and correlate with impaired energetics and subclinical left ventricular dysfunction.

Mahmod M, Francis JM, Pal N, Lewis A, Dass S, De Silva R, Petrou M, Sayeed R, Westaby S, Robson MD, Ashrafian H, Neubauer S, Karamitsos TD.

J Cardiovasc Magn Reson. 2014 Apr 29;16:29. doi: 10.1186/1532-429X-16-29.


Adenosine stress native T1 mapping in severe aortic stenosis: evidence for a role of the intravascular compartment on myocardial T1 values.

Mahmod M, Piechnik SK, Levelt E, Ferreira VM, Francis JM, Lewis A, Pal N, Dass S, Ashrafian H, Neubauer S, Karamitsos TD.

J Cardiovasc Magn Reson. 2014 Nov 20;16:92. doi: 10.1186/s12968-014-0092-y.


Myocardial steatosis and left ventricular contractile dysfunction in patients with severe aortic stenosis.

Mahmod M, Bull S, Suttie JJ, Pal N, Holloway C, Dass S, Myerson SG, Schneider JE, De Silva R, Petrou M, Sayeed R, Westaby S, Clelland C, Francis JM, Ashrafian H, Karamitsos TD, Neubauer S.

Circ Cardiovasc Imaging. 2013 Sep;6(5):808-16. doi: 10.1161/CIRCIMAGING.113.000559. Epub 2013 Jul 5.


Relationship between regional myocardial oxygenation and perfusion in patients with coronary artery disease: insights from cardiovascular magnetic resonance and positron emission tomography.

Karamitsos TD, Leccisotti L, Arnold JR, Recio-Mayoral A, Bhamra-Ariza P, Howells RK, Searle N, Robson MD, Rimoldi OE, Camici PG, Neubauer S, Selvanayagam JB.

Circ Cardiovasc Imaging. 2010 Jan;3(1):32-40. doi: 10.1161/CIRCIMAGING.109.860148. Epub 2009 Nov 17.


Cardiac energetics, oxygenation, and perfusion during increased workload in patients with type 2 diabetes mellitus.

Levelt E, Rodgers CT, Clarke WT, Mahmod M, Ariga R, Francis JM, Liu A, Wijesurendra RS, Dass S, Sabharwal N, Robson MD, Holloway CJ, Rider OJ, Clarke K, Karamitsos TD, Neubauer S.

Eur Heart J. 2016 Dec 7;37(46):3461-3469. doi: 10.1093/eurheartj/ehv442. Epub 2015 Sep 20.


Absolute concentrations of high-energy phosphate metabolites in normal, hypertrophied, and failing human myocardium measured noninvasively with (31)P-SLOOP magnetic resonance spectroscopy.

Beer M, Seyfarth T, Sandstede J, Landschütz W, Lipke C, Köstler H, von Kienlin M, Harre K, Hahn D, Neubauer S.

J Am Coll Cardiol. 2002 Oct 2;40(7):1267-74.


Coronary Microvascular Dysfunction as a Mechanism of Angina in Severe AS: Prospective Adenosine-Stress CMR Study.

Ahn JH, Kim SM, Park SJ, Jeong DS, Woo MA, Jung SH, Lee SC, Park SW, Choe YH, Park PW, Oh JK.

J Am Coll Cardiol. 2016 Mar 29;67(12):1412-1422. doi: 10.1016/j.jacc.2016.01.013.


Navigator-gated 3D blood oxygen level-dependent CMR at 3.0-T for detection of stress-induced myocardial ischemic reactions.

Jahnke C, Gebker R, Manka R, Schnackenburg B, Fleck E, Paetsch I.

JACC Cardiovasc Imaging. 2010 Apr;3(4):375-84. doi: 10.1016/j.jcmg.2009.12.008.


Blunted myocardial oxygenation response during vasodilator stress in patients with hypertrophic cardiomyopathy.

Karamitsos TD, Dass S, Suttie J, Sever E, Birks J, Holloway CJ, Robson MD, Jerosch-Herold M, Watkins H, Neubauer S.

J Am Coll Cardiol. 2013 Mar 19;61(11):1169-76. doi: 10.1016/j.jacc.2012.12.024.


Patients with syndrome X have normal transmural myocardial perfusion and oxygenation: a 3-T cardiovascular magnetic resonance imaging study.

Karamitsos TD, Arnold JR, Pegg TJ, Francis JM, Birks J, Jerosch-Herold M, Neubauer S, Selvanayagam JB.

Circ Cardiovasc Imaging. 2012 Mar;5(2):194-200. doi: 10.1161/CIRCIMAGING.111.969667. Epub 2012 Feb 8. Erratum in: Circ Cardiovasc Imaging. 2012 Jul;5(4):e56.


Myocardial high-energy phosphate and substrate metabolism in swine with moderate left ventricular hypertrophy.

Massie BM, Schaefer S, Garcia J, McKirnan MD, Schwartz GG, Wisneski JA, Weiner MW, White FC.

Circulation. 1995 Mar 15;91(6):1814-23.


Impaired Myocardial Oxygenation Response to Stress in Patients With Chronic Kidney Disease.

Parnham S, Gleadle JM, Bangalore S, Grover S, Perry R, Woodman RJ, De Pasquale CG, Selvanayagam JB.

J Am Heart Assoc. 2015 Aug 10;4(8):e002249. doi: 10.1161/JAHA.115.002249.


Effects of exenatide on cardiac function, perfusion, and energetics in type 2 diabetic patients with cardiomyopathy: a randomized controlled trial against insulin glargine.

Chen WJY, Diamant M, de Boer K, Harms HJ, Robbers LFHJ, van Rossum AC, Kramer MHH, Lammertsma AA, Knaapen P.

Cardiovasc Diabetol. 2017 May 19;16(1):67. doi: 10.1186/s12933-017-0549-z.


Cardiovascular magnetic resonance detects the progression of impaired myocardial perfusion reserve and increased left-ventricular mass in mice fed a high-fat diet.

Naresh NK, Butcher JT, Lye RJ, Chen X, Isakson BE, Gan LM, Kramer CM, Annex BH, Epstein FH.

J Cardiovasc Magn Reson. 2016 Sep 9;18(1):53. doi: 10.1186/s12968-016-0273-y.


Aortic valve replacement in patients with aortic valve stenosis improves myocardial metabolism and diastolic function.

Beyerbacht HP, Lamb HJ, van Der Laarse A, Vliegen HW, Leujes F, Hazekamp MG, de Roos A, van Der Wall EE.

Radiology. 2001 Jun;219(3):637-43.


Automated left ventricular diastolic function evaluation from phase-contrast cardiovascular magnetic resonance and comparison with Doppler echocardiography.

Bollache E, Redheuil A, Clément-Guinaudeau S, Defrance C, Perdrix L, Ladouceur M, Lefort M, De Cesare A, Herment A, Diebold B, Mousseaux E, Kachenoura N.

J Cardiovasc Magn Reson. 2010 Nov 9;12:63. doi: 10.1186/1532-429X-12-63.


No Evidence of Myocardial Oxygen Deprivation in Nonischemic Heart Failure.

Dass S, Holloway CJ, Cochlin LE, Rider OJ, Mahmod M, Robson M, Sever E, Clarke K, Watkins H, Ashrafian H, Karamitsos TD, Neubauer S.

Circ Heart Fail. 2015 Nov;8(6):1088-93. doi: 10.1161/CIRCHEARTFAILURE.114.002169. Epub 2015 Sep 2.


Left ventricular remodeling and hypertrophy in patients with aortic stenosis: insights from cardiovascular magnetic resonance.

Dweck MR, Joshi S, Murigu T, Gulati A, Alpendurada F, Jabbour A, Maceira A, Roussin I, Northridge DB, Kilner PJ, Cook SA, Boon NA, Pepper J, Mohiaddin RH, Newby DE, Pennell DJ, Prasad SK.

J Cardiovasc Magn Reson. 2012 Jul 28;14:50.


Physiologic compensation is supranormal in compensated aortic stenosis: does it return to normal after aortic valve replacement or is it blunted by coexistent coronary artery disease? An intramyocardial magnetic resonance imaging study.

Biederman RW, Doyle M, Yamrozik J, Williams RB, Rathi VK, Vido D, Caruppannan K, Osman N, Bress V, Rayarao G, Biederman CM, Mankad S, Magovern JA, Reichek N.

Circulation. 2005 Aug 30;112(9 Suppl):I429-36.


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