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Items: 1 to 20 of 121

1.

T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease.

Petersen J, Montserrat V, Mujico JR, Loh KL, Beringer DX, van Lummel M, Thompson A, Mearin ML, Schweizer J, Kooy-Winkelaar Y, van Bergen J, Drijfhout JW, Kan WT, La Gruta NL, Anderson RP, Reid HH, Koning F, Rossjohn J.

Nat Struct Mol Biol. 2014 May;21(5):480-8. doi: 10.1038/nsmb.2817. Epub 2014 Apr 28.

PMID:
24777060
2.

Design of gliadin peptide analogues with low affinity for the celiac disease associated HLA-DQ2 protein.

Fraccalvieri D, Motta S, Galliani G, Cavaletti L, Bonati L.

Mol Biosyst. 2014 Aug;10(8):2064-73. doi: 10.1039/c4mb00085d.

PMID:
24841193
3.

Biased T cell receptor usage directed against human leukocyte antigen DQ8-restricted gliadin peptides is associated with celiac disease.

Broughton SE, Petersen J, Theodossis A, Scally SW, Loh KL, Thompson A, van Bergen J, Kooy-Winkelaar Y, Henderson KN, Beddoe T, Tye-Din JA, Mannering SI, Purcell AW, McCluskey J, Anderson RP, Koning F, Reid HH, Rossjohn J.

Immunity. 2012 Oct 19;37(4):611-21. doi: 10.1016/j.immuni.2012.07.013. Epub 2012 Oct 11.

4.

Determinants of gliadin-specific T cell selection in celiac disease.

Petersen J, van Bergen J, Loh KL, Kooy-Winkelaar Y, Beringer DX, Thompson A, Bakker SF, Mulder CJ, Ladell K, McLaren JE, Price DA, Rossjohn J, Reid HH, Koning F.

J Immunol. 2015 Jun 15;194(12):6112-22. doi: 10.4049/jimmunol.1500161. Epub 2015 May 6.

5.

Diverse T Cell Receptor Gene Usage in HLA-DQ8-Associated Celiac Disease Converges into a Consensus Binding Solution.

Petersen J, Kooy-Winkelaar Y, Loh KL, Tran M, van Bergen J, Koning F, Rossjohn J, Reid HH.

Structure. 2016 Oct 4;24(10):1643-1657. doi: 10.1016/j.str.2016.07.010. Epub 2016 Aug 25.

6.

Resistance to celiac disease in humanized HLA-DR3-DQ2-transgenic mice expressing specific anti-gliadin CD4+ T cells.

de Kauwe AL, Chen Z, Anderson RP, Keech CL, Price JD, Wijburg O, Jackson DC, Ladhams J, Allison J, McCluskey J.

J Immunol. 2009 Jun 15;182(12):7440-50. doi: 10.4049/jimmunol.0900233.

7.

Discriminative T-cell receptor recognition of highly homologous HLA-DQ2-bound gluten epitopes.

Dahal-Koirala S, Ciacchi L, Petersen J, Risnes LF, Neumann RS, Christophersen A, Lundin KEA, Reid HH, Qiao SW, Rossjohn J, Sollid LM.

J Biol Chem. 2019 Jan 18;294(3):941-952. doi: 10.1074/jbc.RA118.005736. Epub 2018 Nov 19.

8.

Celiac Immunogenic Potential of α-Gliadin Epitope Variants from Triticum and Aegilops Species.

Ruiz-Carnicer Á, Comino I, Segura V, Ozuna CV, Moreno ML, López-Casado MÁ, Torres MI, Barro F, Sousa C.

Nutrients. 2019 Jan 22;11(2). pii: E220. doi: 10.3390/nu11020220.

9.

TCR sequencing of single cells reactive to DQ2.5-glia-α2 and DQ2.5-glia-ω2 reveals clonal expansion and epitope-specific V-gene usage.

Dahal-Koirala S, Risnes LF, Christophersen A, Sarna VK, Lundin KE, Sollid LM, Qiao SW.

Mucosal Immunol. 2016 May;9(3):587-96. doi: 10.1038/mi.2015.147. Epub 2016 Feb 3.

PMID:
26838051
10.

Celiac disease T-cell epitopes from gamma-gliadins: immunoreactivity depends on the genome of origin, transcript frequency, and flanking protein variation.

Salentijn EM, Mitea DC, Goryunova SV, van der Meer IM, Padioleau I, Gilissen LJ, Koning F, Smulders MJ.

BMC Genomics. 2012 Jun 22;13:277. doi: 10.1186/1471-2164-13-277.

11.

Human genome search in celiac disease: mutated gliadin T-cell-like epitope in two human proteins promotes T-cell activation.

Kumar R, Eastwood AL, Brown ML, Laurie GW.

J Mol Biol. 2002 Jun 7;319(3):593-602.

PMID:
12054857
12.

HLA-DQ2 and -DQ8 signatures of gluten T cell epitopes in celiac disease.

Tollefsen S, Arentz-Hansen H, Fleckenstein B, Molberg O, Ráki M, Kwok WW, Jung G, Lundin KE, Sollid LM.

J Clin Invest. 2006 Aug;116(8):2226-36. Epub 2006 Jul 27.

13.

How T cells taste gluten in celiac disease.

Jabri B, Chen X, Sollid LM.

Nat Struct Mol Biol. 2014 May;21(5):429-31. doi: 10.1038/nsmb.2826. Epub 2014 Apr 28. No abstract available.

PMID:
24777059
14.

HLA-DQ molecules as affinity matrix for identification of gluten T cell epitopes.

Dørum S, Bodd M, Fallang LE, Bergseng E, Christophersen A, Johannesen MK, Qiao SW, Stamnaes J, de Souza GA, Sollid LM.

J Immunol. 2014 Nov 1;193(9):4497-506. doi: 10.4049/jimmunol.1301466. Epub 2014 Sep 26.

15.
16.

Effective shutdown in the expression of celiac disease-related wheat gliadin T-cell epitopes by RNA interference.

Gil-Humanes J, Pistón F, Tollefsen S, Sollid LM, Barro F.

Proc Natl Acad Sci U S A. 2010 Sep 28;107(39):17023-8. doi: 10.1073/pnas.1007773107. Epub 2010 Sep 9.

17.

Posttranslational modification of gluten shapes TCR usage in celiac disease.

Qiao SW, Ráki M, Gunnarsen KS, Løset GÅ, Lundin KE, Sandlie I, Sollid LM.

J Immunol. 2011 Sep 15;187(6):3064-71. doi: 10.4049/jimmunol.1101526. Epub 2011 Aug 17.

18.

A TCRα framework-centered codon shapes a biased T cell repertoire through direct MHC and CDR3β interactions.

Gunnarsen KS, Høydahl LS, Risnes LF, Dahal-Koirala S, Neumann RS, Bergseng E, Frigstad T, Frick R, du Pré MF, Dalhus B, Lundin KE, Qiao SW, Sollid LM, Sandlie I, Løset GÅ.

JCI Insight. 2017 Sep 7;2(17). pii: 95193. doi: 10.1172/jci.insight.95193. eCollection 2017 Sep 7.

19.

Structure of celiac disease-associated HLA-DQ8 and non-associated HLA-DQ9 alleles in complex with two disease-specific epitopes.

Moustakas AK, van de Wal Y, Routsias J, Kooy YM, van Veelen P, Drijfhout JW, Koning F, Papadopoulos GK.

Int Immunol. 2000 Aug;12(8):1157-66.

PMID:
10917890
20.

Single-chain recombinant HLA-DQ2.5/peptide molecules block α2-gliadin-specific pathogenic CD4+ T-cell proliferation and attenuate production of inflammatory cytokines: a potential therapy for celiac disease.

Huan J, Meza-Romero R, Mooney JL, Vandenbark AA, Offner H, Burrows GG.

Mucosal Immunol. 2011 Jan;4(1):112-20. doi: 10.1038/mi.2010.44. Epub 2010 Aug 25.

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