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Items: 1 to 20 of 181

1.

Prevalence of TPMT and ITPA gene polymorphisms and effect on mercaptopurine dosage in Chilean children with acute lymphoblastic leukemia.

Farfan MJ, Salas C, Canales C, Silva F, Villarroel M, Kopp K, Torres JP, Santolaya ME, Morales J.

BMC Cancer. 2014 Apr 28;14:299. doi: 10.1186/1471-2407-14-299.

2.

Thiopurine S-methyltransferase (TPMT) polymorphisms in children with acute lymphoblastic leukemia, and the need for reduction or cessation of 6-mercaptopurine doses during maintenance therapy: the Polish multicenter analysis.

Peregud-Pogorzelski J, Tetera-Rudnicka E, Kurzawski M, Brodkiewicz A, Adrianowska N, Mlynarski W, Januszkiewicz D, Drozdzik M.

Pediatr Blood Cancer. 2011 Oct;57(4):578-82. doi: 10.1002/pbc.23013. Epub 2011 Feb 11.

PMID:
21319286
3.

Epistatic interactions between thiopurine methyltransferase (TPMT) and inosine triphosphate pyrophosphatase (ITPA) variations determine 6-mercaptopurine toxicity in Indian children with acute lymphoblastic leukemia.

Dorababu P, Nagesh N, Linga VG, Gundeti S, Kutala VK, Reddanna P, Digumarti R.

Eur J Clin Pharmacol. 2012 Apr;68(4):379-87. doi: 10.1007/s00228-011-1133-1. Epub 2011 Oct 19.

PMID:
22009189
5.

NUDT15 and TPMT genetic polymorphisms are related to 6-mercaptopurine intolerance in children treated for acute lymphoblastic leukemia at the Children's Cancer Center of Lebanon.

Zgheib NK, Akika R, Mahfouz R, Aridi CA, Ghanem KM, Saab R, Abboud MR, Tarek N, El Solh H, Muwakkit SA.

Pediatr Blood Cancer. 2017 Jan;64(1):146-150. doi: 10.1002/pbc.26189. Epub 2016 Aug 31.

PMID:
27577869
6.

Polymorphism of ITPA 94C>A and risk of adverse effects among patients with acute lymphoblastic leukaemia treated with 6-mercaptopurine.

Wan Rosalina WR, Teh LK, Mohamad N, Nasir A, Yusoff R, Baba AA, Salleh MZ.

J Clin Pharm Ther. 2012 Apr;37(2):237-41. doi: 10.1111/j.1365-2710.2011.01272.x. Epub 2011 May 5.

PMID:
21545474
7.

Analysis of thiopurine S-methyltransferase polymorphism in the population of Serbia and Montenegro and mercaptopurine therapy tolerance in childhood acute lymphoblastic leukemia.

Dokmanovic L, Urosevic J, Janic D, Jovanovic N, Petrucev B, Tosic N, Pavlovic S.

Ther Drug Monit. 2006 Dec;28(6):800-6.

PMID:
17164697
8.

Possible implication of thiopurine S-methyltransferase in occurrence of infectious episodes during maintenance therapy for childhood lymphoblastic leukemia with mercaptopurine.

Dervieux T, Médard Y, Verpillat P, Guigonis V, Duval M, Lescoeur B, Suciu S, Vilmer E, Jacqz-Aigrain E.

Leukemia. 2001 Nov;15(11):1706-12.

PMID:
11681411
9.

The low frequency of defective TPMT alleles in Turkish population: a study on pediatric patients with acute lymphoblastic leukemia.

Tumer TB, Ulusoy G, Adali O, Sahin G, Gozdasoglu S, Arinç E.

Am J Hematol. 2007 Oct;82(10):906-10.

10.

[Importance of genotyping of thiopurine S-methyltransferase in children with acute lymphoblastic leukaemia during maintenance therapy].

Dokmanović L, Janić D, Krstovski N, Zukić B, Tosić N, Pavlović S.

Srp Arh Celok Lek. 2008 Nov-Dec;136(11-12):609-16. Serbian.

11.

Thiopurine S-methyltransferase phenotype-genotype correlation in children with acute lymphoblastic leukemia.

Chrzanowska M, Kuehn M, Januszkiewicz-Lewandowska D, Kurzawski M, Droździk M.

Acta Pol Pharm. 2012 May-Jun;69(3):405-10.

12.

Thiopurine methyltransferase polymorphisms and mercaptopurine tolerance in Turkish children with acute lymphoblastic leukemia.

Albayrak M, Konyssova U, Kaya Z, Gursel T, Guntekin S, Percin EF, Kocak U.

Cancer Chemother Pharmacol. 2011 Nov;68(5):1155-9. doi: 10.1007/s00280-011-1599-7. Epub 2011 Mar 13.

PMID:
21400026
13.

Genetic polymorphism of inosine triphosphate pyrophosphatase is a determinant of mercaptopurine metabolism and toxicity during treatment for acute lymphoblastic leukemia.

Stocco G, Cheok MH, Crews KR, Dervieux T, French D, Pei D, Yang W, Cheng C, Pui CH, Relling MV, Evans WE.

Clin Pharmacol Ther. 2009 Feb;85(2):164-72. doi: 10.1038/clpt.2008.154. Epub 2008 Aug 6.

14.

TPMT and ITPA genetic variants in Lithuanian inflammatory bowel disease patients: Prevalence and azathioprine-related side effects.

Steponaitiene R, Kupcinskas J, Survilaite S, Varkalaite G, Jonaitis L, Kiudelis G, Denapiene G, Valantinas J, Skieceviciene J, Kupcinskas L.

Adv Med Sci. 2016 Mar;61(1):135-40. doi: 10.1016/j.advms.2015.09.008. Epub 2015 Dec 10.

PMID:
26674571
15.

[Relationship between single nucleotide polymorphisms in thiopurine methyltransferase gene and tolerance to thiopurines in acute leukemia].

Ma XL, Zhu P, Wu MY, Li ZG, Hu YM.

Zhonghua Er Ke Za Zhi. 2003 Dec;41(12):929-33. Chinese.

PMID:
14723818
16.

Frequency of ITPA gene polymorphisms in Iranian patients with acute lymphoblastic leukemia and prediction of its myelosuppressive effects.

Azimi F, Mortazavi Y, Alavi S, Khalili M, Ramazani A.

Leuk Res. 2015 Oct;39(10):1048-54. doi: 10.1016/j.leukres.2015.06.016. Epub 2015 Jul 4.

PMID:
26242828
17.

Thiopurine S-methyltransferase gene polymorphism and 6-mercaptopurine dose intensity in Indian children with acute lymphoblastic leukemia.

Kapoor G, Sinha R, Naithani R, Chandgothia M.

Leuk Res. 2010 Aug;34(8):1023-6. doi: 10.1016/j.leukres.2010.01.029. Epub 2010 Feb 13.

PMID:
20153897
18.

Allele frequency of thiopurine methyltransferase and inosine triphosphate pyrophosphatase gene polymorphisms in Korean patients with inflammatory bowel diseases.

Cheon JH, Kim JH, Kim BY, Kim SW, Hong SY, Eun CS, Hong SS, Byeon JS, Kim TI, Han DS, Yang SK, Lee KR, Kim WH.

Hepatogastroenterology. 2009 Mar-Apr;56(90):421-3.

PMID:
19579612
19.

Thiopurine methyltransferase polymorphisms in a multiracial asian population and children with acute lymphoblastic leukemia.

Kham SK, Tan PL, Tay AH, Heng CK, Yeoh AE, Quah TC.

J Pediatr Hematol Oncol. 2002 Jun-Jul;24(5):353-9.

PMID:
12142782
20.

Genetic variants of thiopurine and folate metabolic pathways determine 6-MP-mediated hematological toxicity in childhood ALL.

Dorababu P, Naushad SM, Linga VG, Gundeti S, Nagesh N, Kutala VK, Reddanna P, Digumarti R.

Pharmacogenomics. 2012 Jul;13(9):1001-8. doi: 10.2217/pgs.12.70.

PMID:
22838948

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