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Detection and Treatment of Long-Chain Omega-3 Fatty Acid Deficiency in Adolescents with SSRI-Resistant Major Depressive Disorder.

McNamara RK, Strimpfel J, Jandacek R, Rider T, Tso P, Welge JA, Strawn JR, Delbello MP.

PharmaNutrition. 2014 Apr 1;2(2):38-46.


Effects of fish oil supplementation on prefrontal metabolite concentrations in adolescents with major depressive disorder: a preliminary 1H MRS study.

McNamara RK, Jandacek R, Rider T, Tso P, Chu WJ, Weber WA, Welge JA, Strawn JR, Adler CM, DelBello MP.

Nutr Neurosci. 2016 May;19(4):145-55. doi: 10.1179/1476830514Y.0000000135. Epub 2016 Mar 2.


Adolescents with or at ultra-high risk for bipolar disorder exhibit erythrocyte docosahexaenoic acid and eicosapentaenoic acid deficits: a candidate prodromal risk biomarker.

McNamara RK, Jandacek R, Tso P, Blom TJ, Welge JA, Strawn JR, Adler CM, Strakowski SM, DelBello MP.

Early Interv Psychiatry. 2016 Jun;10(3):203-11. doi: 10.1111/eip.12282. Epub 2015 Oct 20.


Selective deficits in erythrocyte docosahexaenoic acid composition in adult patients with bipolar disorder and major depressive disorder.

McNamara RK, Jandacek R, Rider T, Tso P, Dwivedi Y, Pandey GN.

J Affect Disord. 2010 Oct;126(1-2):303-11. doi: 10.1016/j.jad.2010.03.015. Epub 2010 Apr 21.


First-episode bipolar disorder is associated with erythrocyte membrane docosahexaenoic acid deficits: Dissociation from clinical response to lithium or quetiapine.

McNamara RK, Jandacek R, Tso P, Blom TJ, Welge JA, Strawn JR, Adler CM, DelBello MP, Strakowski SM.

Psychiatry Res. 2015 Dec 15;230(2):447-53. doi: 10.1016/j.psychres.2015.09.035. Epub 2015 Oct 9.


Edivoxetine compared to placebo as adjunctive therapy to selective serotonin reuptake inhibitors in the prevention of symptom re-emergence in major depressive disorder.

Oakes TM, Dellva MA, Waterman K, Greenbaum M, Poppe C, Goldberger C, Ahl J, Perahia DG.

Curr Med Res Opin. 2015 Jun;31(6):1179-89. doi: 10.1185/03007995.2015.1037732. Epub 2015 May 6.


Detection and treatment of omega-3 fatty acid deficiency in psychiatric practice: Rationale and implementation.

Messamore E, McNamara RK.

Lipids Health Dis. 2016 Feb 10;15:25. doi: 10.1186/s12944-016-0196-5. Review.


Low doses of eicosapentaenoic acid and docosahexaenoic acid from fish oil dose-dependently decrease serum triglyceride concentrations in the presence of plant sterols in hypercholesterolemic men and women.

Ras RT, Demonty I, Zebregs YE, Quadt JF, Olsson J, Trautwein EA.

J Nutr. 2014 Oct;144(10):1564-70. doi: 10.3945/jn.114.192229. Epub 2014 Aug 13.


Fatty acid metabolism and its longitudinal relationship with the hypothalamic-pituitary-adrenal axis in major depression: Associations with prospective antidepressant response.

Mocking RJ, Verburg HF, Westerink AM, Assies J, Vaz FM, Koeter MW, Ruhé HG, Schene AH.

Psychoneuroendocrinology. 2015 Sep;59:1-13. doi: 10.1016/j.psyneuen.2015.04.027. Epub 2015 May 11.


Low unesterified:esterified eicosapentaenoic acid (EPA) plasma concentration ratio is associated with bipolar disorder episodes, and omega-3 plasma concentrations are altered by treatment.

Saunders EF, Reider A, Singh G, Gelenberg AJ, Rapoport SI.

Bipolar Disord. 2015 Nov;17(7):729-42. doi: 10.1111/bdi.12337. Epub 2015 Oct 1.


The mothers, Omega-3 and mental health study.

Mozurkewich E, Chilimigras J, Klemens C, Keeton K, Allbaugh L, Hamilton S, Berman D, Vazquez D, Marcus S, Djuric Z, Vahratian A.

BMC Pregnancy Childbirth. 2011 Jun 22;11:46. doi: 10.1186/1471-2393-11-46.


Mitigation of Inflammation-Induced Mood Dysregulation by Long-Chain Omega-3 Fatty Acids.

McNamara RK.

J Am Coll Nutr. 2015;34 Suppl 1:48-55. doi: 10.1080/07315724.2015.1080527.


Effects of 1-year treatment with highly purified omega-3 fatty acids on depression after myocardial infarction: results from the OMEGA trial.

Zimmer R, Riemer T, Rauch B, Schneider S, Schiele R, Gohlke H, Diller F, Steinbeck G, Katus H, Senges J; OMEGA-Study Group.

J Clin Psychiatry. 2013 Nov;74(11):e1037-45. doi: 10.4088/JCP.13m08453.


Effects of n-3 fatty acids on depressive symptoms and dispositional optimism after myocardial infarction.

Giltay EJ, Geleijnse JM, Kromhout D.

Am J Clin Nutr. 2011 Dec;94(6):1442-50. doi: 10.3945/ajcn.111.018259. Epub 2011 Oct 26.


Role of Long-Chain Omega-3 Fatty Acids in Psychiatric Practice.

McNamara RK, Strawn JR.

PharmaNutrition. 2013 Apr;1(2):41-49.


Effects of fish-oil and folate supplementation of pregnant women on maternal and fetal plasma concentrations of docosahexaenoic acid and eicosapentaenoic acid: a European randomized multicenter trial.

Krauss-Etschmann S, Shadid R, Campoy C, Hoster E, Demmelmair H, Jiménez M, Gil A, Rivero M, Veszprémi B, Decsi T, Koletzko BV; Nutrition and Health Lifestyle (NUHEAL) Study Group.

Am J Clin Nutr. 2007 May;85(5):1392-400.


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