Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 146

1.

LC-MS/MS and GC-MS/MS measurement of plasma and urine di-paracetamol and 3-nitro-paracetamol: proof-of-concept studies on a novel human model of oxidative stress based on oral paracetamol administration.

Trettin A, Modun D, Madunic S, Vukovic J, Radman M, Batkai S, Thum T, Jordan J, Tsikas D.

J Chromatogr B Analyt Technol Biomed Life Sci. 2014 May 15;959:71-81. doi: 10.1016/j.jchromb.2014.03.031. Epub 2014 Apr 2.

PMID:
24768921
2.

Trapping of NAPQI, the intermediate toxic paracetamol metabolite, by aqueous sulfide (S²⁻) and analysis by GC-MS/MS.

Trettin A, Batkai S, Thum T, Jordan J, Tsikas D.

J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Jul 15;963:99-105. doi: 10.1016/j.jchromb.2014.05.050. Epub 2014 Jun 2.

PMID:
24950097
3.

In-source formation of N-acetyl-p-benzoquinone imine (NAPQI), the putatively toxic acetaminophen (paracetamol) metabolite, after derivatization with pentafluorobenzyl bromide and GC-ECNICI-MS analysis.

Tsikas D, Trettin A, Zörner AA, Gutzki FM.

J Chromatogr B Analyt Technol Biomed Life Sci. 2011 May 15;879(17-18):1476-84. doi: 10.1016/j.jchromb.2011.01.025. Epub 2011 Feb 4.

PMID:
21353649
4.

LC-MS/MS analysis of uncommon paracetamol metabolites derived through in vitro polymerization and nitration reactions in liquid nitrogen.

Trettin A, Jordan J, Tsikas D.

J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Sep 1;966:171-8. doi: 10.1016/j.jchromb.2013.11.055. Epub 2013 Dec 4.

PMID:
24365200
5.

Quantification of acetaminophen (paracetamol) in human plasma and urine by stable isotope-dilution GC-MS and GC-MS/MS as pentafluorobenzyl ether derivative.

Trettin A, Zoerner AA, Böhmer A, Gutzki FM, Stichtenoth DO, Jordan J, Tsikas D.

J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Aug 1;879(23):2274-80. doi: 10.1016/j.jchromb.2011.06.012. Epub 2011 Jun 15.

PMID:
21733763
6.

Specific GC-MS/MS stable-isotope dilution methodology for free 9- and 10-nitro-oleic acid in human plasma challenges previous LC-MS/MS reports.

Tsikas D, Zoerner A, Mitschke A, Homsi Y, Gutzki FM, Jordan J.

J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Sep 15;877(26):2895-908. doi: 10.1016/j.jchromb.2008.12.062. Epub 2009 Jan 6.

PMID:
19162569
7.
8.

Bioavailability of two oral-tablet and two oral-suspension formulations of naproxen sodium/paracetamol (acetaminophen): single-dose, randomized, open-label, two-period crossover comparisons in healthy Mexican adult subjects.

Palma-Aguirre JA, Villalpando-Hernández J, Novoa-Heckel G, Oliva I, Cariño L, López-Bojórquez E, Burke-Fraga V, Namur S, González-de la Parra M.

Clin Ther. 2009 Feb;31(2):399-410. doi: 10.1016/j.clinthera.2009.02.002.

PMID:
19302912
9.

Measurement of 3-nitro-tyrosine in human plasma and urine by gas chromatography-tandem mass spectrometry.

Tsikas D, Mitschke A, Gutzki FM.

Methods Mol Biol. 2012;828:255-70. doi: 10.1007/978-1-61779-445-2_20.

PMID:
22125150
10.

Bio-generation of stable isotope-labeled internal standards for absolute and relative quantitation of phase II drug metabolites in plasma samples using LC-MS/MS.

Li P, Li Z, Beck WD, Callahan PM, Terry AV Jr, Bar-Peled M, Bartlett MG.

Anal Bioanal Chem. 2015 May;407(14):4053-63. doi: 10.1007/s00216-015-8614-5. Epub 2015 Mar 25.

PMID:
25804729
11.

On-line liquid chromatography coupled with high field NMR and mass spectrometry (LC-NMR-MS): a new technique for drug metabolite structure elucidation.

Burton KI, Everett JR, Newman MJ, Pullen FS, Richards DS, Swanson AG.

J Pharm Biomed Anal. 1997 Aug;15(12):1903-12.

PMID:
9278896
12.

Contribution of CYP2E1 and CYP3A to acetaminophen reactive metabolite formation.

Manyike PT, Kharasch ED, Kalhorn TF, Slattery JT.

Clin Pharmacol Ther. 2000 Mar;67(3):275-82.

PMID:
10741631
13.

Pediatric microdose study of [(14)C]paracetamol to study drug metabolism using accelerated mass spectrometry: proof of concept.

Mooij MG, van Duijn E, Knibbe CA, Windhorst AD, Hendrikse NH, Vaes WH, Spaans E, Fabriek BO, Sandman H, Grossouw D, Hanff LM, Janssen PJ, Koch BC, Tibboel D, de Wildt SN.

Clin Pharmacokinet. 2014 Nov;53(11):1045-51. doi: 10.1007/s40262-014-0176-8.

14.

Determination of 3-nitrotyrosine in human urine at the basal state by gas chromatography-tandem mass spectrometry and evaluation of the excretion after oral intake.

Tsikas D, Mitschke A, Suchy MT, Gutzki FM, Stichtenoth DO.

J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Nov 15;827(1):146-56. Epub 2005 Apr 22.

PMID:
16260382
15.

Rapid determination of N-acetyl-4-aminophenol (paracetamol) in urine by tandem mass spectrometry coupled with on-line clean-up by two dimensional turbulent flow/reversed phase liquid chromatography.

Modick H, Schütze A, Pälmke C, Weiss T, Brüning T, Koch HM.

J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Apr 15;925:33-9. doi: 10.1016/j.jchromb.2013.02.023. Epub 2013 Feb 27.

PMID:
23518644
16.
17.

GC-MS/MS and LC-MS/MS studies on unlabelled and deuterium-labelled oleic acid (C18:1) reactions with peroxynitrite (O=N-O-O⁻) in buffer and hemolysate support the pM/nM-range of nitro-oleic acids in human plasma.

Trettin A, Böhmer A, Zoerner AA, Gutzki FM, Jordan J, Tsikas D.

J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Aug 1;964:172-9. doi: 10.1016/j.jchromb.2014.01.016. Epub 2014 Jan 15.

PMID:
24507967
18.

Development, validation and biomedical applications of stable-isotope dilution GC-MS and GC-MS/MS techniques for circulating malondialdehyde (MDA) after pentafluorobenzyl bromide derivatization: MDA as a biomarker of oxidative stress and its relation to 15(S)-8-iso-prostaglandin F2α and nitric oxide (NO).

Tsikas D, Rothmann S, Schneider JY, Suchy MT, Trettin A, Modun D, Stuke N, Maassen N, Frölich JC.

J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Apr 15;1019:95-111. doi: 10.1016/j.jchromb.2015.10.009. Epub 2015 Oct 17.

PMID:
26522895
20.

Development of an HPLC-MS/MS method for the selective determination of paracetamol metabolites in mouse urine.

Hewavitharana AK, Lee S, Dawson PA, Markovich D, Shaw PN.

Anal Biochem. 2008 Mar 1;374(1):106-11. Epub 2007 Nov 17.

PMID:
18082126

Supplemental Content

Support Center