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Items: 1 to 20 of 103

1.

Pkd1 regulates lymphatic vascular morphogenesis during development.

Coxam B, Sabine A, Bower NI, Smith KA, Pichol-Thievend C, Skoczylas R, Astin JW, Frampton E, Jaquet M, Crosier PS, Parton RG, Harvey NL, Petrova TV, Schulte-Merker S, Francois M, Hogan BM.

Cell Rep. 2014 May 8;7(3):623-33. doi: 10.1016/j.celrep.2014.03.063. Epub 2014 Apr 24.

2.

Polycystin signaling is required for directed endothelial cell migration and lymphatic development.

Outeda P, Huso DL, Fisher SA, Halushka MK, Kim H, Qian F, Germino GG, Watnick T.

Cell Rep. 2014 May 8;7(3):634-44. doi: 10.1016/j.celrep.2014.03.064. Epub 2014 Apr 24.

3.

An Evolutionarily Conserved Role for Polydom/Svep1 During Lymphatic Vessel Formation.

Karpanen T, Padberg Y, van de Pavert SA, Dierkes C, Morooka N, Peterson-Maduro J, van de Hoek G, Adrian M, Mochizuki N, Sekiguchi K, Kiefer F, Schulte D, Schulte-Merker S.

Circ Res. 2017 Apr 14;120(8):1263-1275. doi: 10.1161/CIRCRESAHA.116.308813. Epub 2017 Feb 8.

4.

TGFβ signaling is required for sprouting lymphangiogenesis during lymphatic network development in the skin.

James JM, Nalbandian A, Mukouyama YS.

Development. 2013 Sep;140(18):3903-14. doi: 10.1242/dev.095026. Epub 2013 Aug 14.

5.

Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling.

Morooka N, Futaki S, Sato-Nishiuchi R, Nishino M, Totani Y, Shimono C, Nakano I, Nakajima H, Mochizuki N, Sekiguchi K.

Circ Res. 2017 Apr 14;120(8):1276-1288. doi: 10.1161/CIRCRESAHA.116.308825. Epub 2017 Feb 8.

PMID:
28179430
6.

Impaired glomerulogenesis and endothelial cell migration in Pkd1-deficient renal organ cultures.

Rowe I, Chiaravalli M, Piontek KB, Germino GG, Boletta A.

Biochem Biophys Res Commun. 2014 Feb 21;444(4):473-9. doi: 10.1016/j.bbrc.2014.01.068. Epub 2014 Jan 25.

7.

Progressive renal distortion by multiple cysts in transgenic mice expressing artificial microRNAs against Pkd1.

Wang E, Hsieh-Li HM, Chiou YY, Chien YL, Ho HH, Chin HJ, Wang CK, Liang SC, Jiang ST.

J Pathol. 2010 Nov;222(3):238-48. doi: 10.1002/path.2765.

PMID:
20814903
8.

Functional polycystin-1 dosage governs autosomal dominant polycystic kidney disease severity.

Hopp K, Ward CJ, Hommerding CJ, Nasr SH, Tuan HF, Gainullin VG, Rossetti S, Torres VE, Harris PC.

J Clin Invest. 2012 Nov;122(11):4257-73. doi: 10.1172/JCI64313. Epub 2012 Oct 15.

9.

Divergence of zebrafish and mouse lymphatic cell fate specification pathways.

van Impel A, Zhao Z, Hermkens DM, Roukens MG, Fischer JC, Peterson-Maduro J, Duckers H, Ober EA, Ingham PW, Schulte-Merker S.

Development. 2014 Mar;141(6):1228-38. doi: 10.1242/dev.105031. Epub 2014 Feb 12.

10.

Fatty Acid Oxidation is Impaired in An Orthologous Mouse Model of Autosomal Dominant Polycystic Kidney Disease.

Menezes LF, Lin CC, Zhou F, Germino GG.

EBioMedicine. 2016 Jan 26;5:183-92. doi: 10.1016/j.ebiom.2016.01.027. eCollection 2016 Mar.

11.

Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation.

Lu W, Peissel B, Babakhanlou H, Pavlova A, Geng L, Fan X, Larson C, Brent G, Zhou J.

Nat Genet. 1997 Oct;17(2):179-81.

PMID:
9326937
12.

Protein kinase X (PRKX) can rescue the effects of polycystic kidney disease-1 gene (PKD1) deficiency.

Li X, Burrow CR, Polgar K, Hyink DP, Gusella GL, Wilson PD.

Biochim Biophys Acta. 2008 Jan;1782(1):1-9. Epub 2007 Sep 29.

13.

Neuropilin-2 mediates VEGF-C-induced lymphatic sprouting together with VEGFR3.

Xu Y, Yuan L, Mak J, Pardanaud L, Caunt M, Kasman I, Larrivée B, Del Toro R, Suchting S, Medvinsky A, Silva J, Yang J, Thomas JL, Koch AW, Alitalo K, Eichmann A, Bagri A.

J Cell Biol. 2010 Jan 11;188(1):115-30. doi: 10.1083/jcb.200903137.

14.

mafba is a downstream transcriptional effector of Vegfc signaling essential for embryonic lymphangiogenesis in zebrafish.

Koltowska K, Paterson S, Bower NI, Baillie GJ, Lagendijk AK, Astin JW, Chen H, Francois M, Crosier PS, Taft RJ, Simons C, Smith KA, Hogan BM.

Genes Dev. 2015 Aug 1;29(15):1618-30. doi: 10.1101/gad.263210.115.

15.

Planar cell polarity protein Celsr1 regulates endothelial adherens junctions and directed cell rearrangements during valve morphogenesis.

Tatin F, Taddei A, Weston A, Fuchs E, Devenport D, Tissir F, Makinen T.

Dev Cell. 2013 Jul 15;26(1):31-44. doi: 10.1016/j.devcel.2013.05.015. Epub 2013 Jun 20.

16.

A Pkd1-Fbn1 genetic interaction implicates TGF-β signaling in the pathogenesis of vascular complications in autosomal dominant polycystic kidney disease.

Liu D, Wang CJ, Judge DP, Halushka MK, Ni J, Habashi JP, Moslehi J, Bedja D, Gabrielson KL, Xu H, Qian F, Huso D, Dietz HC, Germino GG, Watnick T.

J Am Soc Nephrol. 2014 Jan;25(1):81-91. doi: 10.1681/ASN.2012050486. Epub 2013 Sep 26.

17.

A human PKD1 transgene generates functional polycystin-1 in mice and is associated with a cystic phenotype.

Pritchard L, Sloane-Stanley JA, Sharpe JA, Aspinwall R, Lu W, Buckle V, Strmecki L, Walker D, Ward CJ, Alpers CE, Zhou J, Wood WG, Harris PC.

Hum Mol Genet. 2000 Nov 1;9(18):2617-27.

PMID:
11063721
18.

Nedd9 restrains renal cystogenesis in Pkd1-/- mice.

Nikonova AS, Plotnikova OV, Serzhanova V, Efimov A, Bogush I, Cai KQ, Hensley HH, Egleston BL, Klein-Szanto A, Seeger-Nukpezah T, Golemis EA.

Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12859-64. doi: 10.1073/pnas.1405362111. Epub 2014 Aug 19.

19.

Vegfc acts through ERK to induce sprouting and differentiation of trunk lymphatic progenitors.

Shin M, Male I, Beane TJ, Villefranc JA, Kok FO, Zhu LJ, Lawson ND.

Development. 2016 Oct 15;143(20):3785-3795. Epub 2016 Sep 12. Erratum in: Development. 2017 Feb 1;144(3):531.

20.

Scattered Deletion of PKD1 in Kidneys Causes a Cystic Snowball Effect and Recapitulates Polycystic Kidney Disease.

Leonhard WN, Zandbergen M, Veraar K, van den Berg S, van der Weerd L, Breuning M, de Heer E, Peters DJ.

J Am Soc Nephrol. 2015 Jun;26(6):1322-33. doi: 10.1681/ASN.2013080864. Epub 2014 Oct 31.

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