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Items: 1 to 20 of 130

1.

Allosteric sodium in class A GPCR signaling.

Katritch V, Fenalti G, Abola EE, Roth BL, Cherezov V, Stevens RC.

Trends Biochem Sci. 2014 May;39(5):233-44. doi: 10.1016/j.tibs.2014.03.002.

2.

Allosteric effects of sodium ion binding on activation of the m3 muscarinic g-protein-coupled receptor.

Miao Y, Caliman AD, McCammon JA.

Biophys J. 2015 Apr 7;108(7):1796-806. doi: 10.1016/j.bpj.2015.03.003.

3.

7TM Domain Structure of Adhesion GPCRs.

de Graaf C, Nijmeijer S, Wolf S, Ernst OP.

Handb Exp Pharmacol. 2016;234:43-66.

PMID:
27832483
4.

Emerging opportunities for allosteric modulation of G-protein coupled receptors.

Wang CI, Lewis RJ.

Biochem Pharmacol. 2013 Jan 15;85(2):153-62. doi: 10.1016/j.bcp.2012.09.001. Review.

PMID:
22975406
5.

Allosteric mechanisms of G protein-Coupled Receptor signaling: a structural perspective.

Thaker TM, Kaya AI, Preininger AM, Hamm HE, Iverson TM.

Methods Mol Biol. 2012;796:133-74. doi: 10.1007/978-1-61779-334-9_8.

6.

Emerging structural insights into biased GPCR signaling.

Shukla AK, Singh G, Ghosh E.

Trends Biochem Sci. 2014 Dec;39(12):594-602. doi: 10.1016/j.tibs.2014.10.001. Review.

PMID:
25458114
7.

The role of a sodium ion binding site in the allosteric modulation of the A(2A) adenosine G protein-coupled receptor.

Gutiérrez-de-Terán H, Massink A, Rodríguez D, Liu W, Han GW, Joseph JS, Katritch I, Heitman LH, Xia L, Ijzerman AP, Cherezov V, Katritch V, Stevens RC.

Structure. 2013 Dec 3;21(12):2175-85. doi: 10.1016/j.str.2013.09.020.

8.

Allosteric inhibition of g-protein coupled receptor oligomerization: strategies and challenges for drug development.

Hurevich M, Talhami A, Shalev DE, Gilon C.

Curr Top Med Chem. 2014;14(15):1842-63. Review.

PMID:
25175995
9.

Novel Allosteric Modulators of G Protein-coupled Receptors.

Gentry PR, Sexton PM, Christopoulos A.

J Biol Chem. 2015 Aug 7;290(32):19478-88. doi: 10.1074/jbc.R115.662759. Review.

10.

Allosteric coupling from G protein to the agonist-binding pocket in GPCRs.

DeVree BT, Mahoney JP, Vélez-Ruiz GA, Rasmussen SG, Kuszak AJ, Edwald E, Fung JJ, Manglik A, Masureel M, Du Y, Matt RA, Pardon E, Steyaert J, Kobilka BK, Sunahara RK.

Nature. 2016 Jul 7;535(7610):182-6.

PMID:
27362234
11.

Structural biology of glycoprotein hormones and their receptors: insights to signaling.

Jiang X, Dias JA, He X.

Mol Cell Endocrinol. 2014 Jan 25;382(1):424-51. doi: 10.1016/j.mce.2013.08.021. Review.

12.

Allosteric modulation of family C G-protein-coupled receptors: from molecular insights to therapeutic perspectives.

Urwyler S.

Pharmacol Rev. 2011 Mar;63(1):59-126. doi: 10.1124/pr.109.002501. Review.

13.

Identification of G protein-coupled receptor signaling pathway proteins in marine diatoms using comparative genomics.

Port JA, Parker MS, Kodner RB, Wallace JC, Armbrust EV, Faustman EM.

BMC Genomics. 2013 Jul 24;14:503. doi: 10.1186/1471-2164-14-503.

14.

Strategies for the identification of allosteric modulators of G-protein-coupled receptors.

Burford NT, Watson J, Bertekap R, Alt A.

Biochem Pharmacol. 2011 Mar 15;81(6):691-702. doi: 10.1016/j.bcp.2010.12.012. Review.

PMID:
21184747
15.

Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator.

Wu H, Wang C, Gregory KJ, Han GW, Cho HP, Xia Y, Niswender CM, Katritch V, Meiler J, Cherezov V, Conn PJ, Stevens RC.

Science. 2014 Apr 4;344(6179):58-64. doi: 10.1126/science.1249489.

16.

Structural and functional insights into the juxtamembranous amino-terminal tail and extracellular loop regions of class B GPCRs.

Dong M, Koole C, Wootten D, Sexton PM, Miller LJ.

Br J Pharmacol. 2014 Mar;171(5):1085-101. doi: 10.1111/bph.12293. Review.

17.

G protein-coupled receptors--recent advances.

Latek D, Modzelewska A, Trzaskowski B, Palczewski K, Filipek S.

Acta Biochim Pol. 2012;59(4):515-29. Review.

18.

Dualsteric GPCR targeting: a novel route to binding and signaling pathway selectivity.

Antony J, Kellershohn K, Mohr-Andrä M, Kebig A, Prilla S, Muth M, Heller E, Disingrini T, Dallanoce C, Bertoni S, Schrobang J, Tränkle C, Kostenis E, Christopoulos A, Höltje HD, Barocelli E, De Amici M, Holzgrabe U, Mohr K.

FASEB J. 2009 Feb;23(2):442-50. doi: 10.1096/fj.08-114751.

19.

Domain coupling in GPCRs: the engine for induced conformational changes.

Unal H, Karnik SS.

Trends Pharmacol Sci. 2012 Feb;33(2):79-88. doi: 10.1016/j.tips.2011.09.007. Review.

20.

Sticky signaling--adhesion class G protein-coupled receptors take the stage.

Langenhan T, Aust G, Hamann J.

Sci Signal. 2013 May 21;6(276):re3. doi: 10.1126/scisignal.2003825. Review.

PMID:
23695165
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