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Items: 1 to 20 of 102

1.

A crucial role for DOK1 in PDGF-BB-stimulated glioma cell invasion through p130Cas and Rap1 signalling.

Barrett A, Evans IM, Frolov A, Britton G, Pellet-Many C, Yamaji M, Mehta V, Bandopadhyay R, Li N, Brandner S, Zachary IC, Frankel P.

J Cell Sci. 2014 Jun 15;127(Pt 12):2647-58. doi: 10.1242/jcs.135988. Epub 2014 Apr 24. Erratum in: J Cell Sci. 2014 Aug 1;127(Pt 15):3397.

2.

HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells.

Natarajan M, Stewart JE, Golemis EA, Pugacheva EN, Alexandropoulos K, Cox BD, Wang W, Grammer JR, Gladson CL.

Oncogene. 2006 Mar 16;25(12):1721-32. Erratum in: Oncogene. 2007 Nov 8;26(51):7282.

PMID:
16288224
3.

Neuropilin-1 mediates PDGF stimulation of vascular smooth muscle cell migration and signalling via p130Cas.

Pellet-Many C, Frankel P, Evans IM, Herzog B, Jünemann-Ramírez M, Zachary IC.

Biochem J. 2011 May 1;435(3):609-18. doi: 10.1042/BJ20100580.

5.

Activation of Rac1 by Src-dependent phosphorylation of Dock180(Y1811) mediates PDGFRα-stimulated glioma tumorigenesis in mice and humans.

Feng H, Hu B, Liu KW, Li Y, Lu X, Cheng T, Yiin JJ, Lu S, Keezer S, Fenton T, Furnari FB, Hamilton RL, Vuori K, Sarkaria JN, Nagane M, Nishikawa R, Cavenee WK, Cheng SY.

J Clin Invest. 2011 Dec;121(12):4670-84. doi: 10.1172/JCI58559. Epub 2011 Nov 14.

6.

Tamoxifen treatment promotes phosphorylation of the adhesion molecules, p130Cas/BCAR1, FAK and Src, via an adhesion-dependent pathway.

Cowell LN, Graham JD, Bouton AH, Clarke CL, O'Neill GM.

Oncogene. 2006 Dec 7;25(58):7597-607. Epub 2006 Jun 26.

PMID:
16799644
7.

Mutation of a Src phosphorylation site in the PDGF beta-receptor leads to increased PDGF-stimulated chemotaxis but decreased mitogenesis.

Hansen K, Johnell M, Siegbahn A, Rorsman C, Engström U, Wernstedt C, Heldin CH, Rönnstrand L.

EMBO J. 1996 Oct 1;15(19):5299-313.

8.

Src tyrosine kinase mediates platelet-derived growth factor BB-induced and redox-dependent migration in metanephric mesenchymal cells.

Wagner B, Gorin Y.

Am J Physiol Renal Physiol. 2014 Jan 1;306(1):F85-97. doi: 10.1152/ajprenal.00371.2013. Epub 2013 Nov 6.

9.

Chondroitin sulphate-modified neuropilin 1 is expressed in human tumour cells and modulates 3D invasion in the U87MG human glioblastoma cell line through a p130Cas-mediated pathway.

Frankel P, Pellet-Many C, Lehtolainen P, D'Abaco GM, Tickner ML, Cheng L, Zachary IC.

EMBO Rep. 2008 Oct;9(10):983-9. doi: 10.1038/embor.2008.151. Epub 2008 Aug 15.

10.

Identification of Tyr-762 in the platelet-derived growth factor alpha-receptor as the binding site for Crk proteins.

Yokote K, Hellman U, Ekman S, Saito Y, Rönnstrand L, Saito Y, Heldin CH, Mori S.

Oncogene. 1998 Mar 12;16(10):1229-39.

13.

The Ubiquitin Ligases c-Cbl and Cbl-b Negatively Regulate Platelet-derived Growth Factor (PDGF) BB-induced Chemotaxis by Affecting PDGF Receptor β (PDGFRβ) Internalization and Signaling.

Rorsman C, Tsioumpekou M, Heldin CH, Lennartsson J.

J Biol Chem. 2016 May 27;291(22):11608-18. doi: 10.1074/jbc.M115.705814. Epub 2016 Apr 5.

PMID:
27048651
14.
16.

The Fer tyrosine kinase is important for platelet-derived growth factor-BB-induced signal transducer and activator of transcription 3 (STAT3) protein phosphorylation, colony formation in soft agar, and tumor growth in vivo.

Lennartsson J, Ma H, Wardega P, Pelka K, Engström U, Hellberg C, Heldin CH.

J Biol Chem. 2013 May 31;288(22):15736-44. doi: 10.1074/jbc.M113.476424. Epub 2013 Apr 15.

17.

Ets-1 mediates platelet-derived growth factor-BB-induced thrombomodulin expression in human vascular smooth muscle cells.

Lo IC, Lin TM, Chou LH, Liu SL, Wu LW, Shi GY, Wu HL, Jiang MJ.

Cardiovasc Res. 2009 Mar 1;81(4):771-9. doi: 10.1093/cvr/cvn351. Epub 2008 Dec 17.

PMID:
19091791
18.

Role of Dok1 in cell signaling mediated by RET tyrosine kinase.

Murakami H, Yamamura Y, Shimono Y, Kawai K, Kurokawa K, Takahashi M.

J Biol Chem. 2002 Sep 6;277(36):32781-90. Epub 2002 Jun 26.

19.

Beta-platelet-derived growth factor receptor mediates motility and growth of Ewing's sarcoma cells.

Uren A, Merchant MS, Sun CJ, Vitolo MI, Sun Y, Tsokos M, Illei PB, Ladanyi M, Passaniti A, Mackall C, Toretsky JA.

Oncogene. 2003 Apr 17;22(15):2334-42.

PMID:
12700668
20.

Requirement of the p130CAS-Crk coupling for metastasis suppressor KAI1/CD82-mediated inhibition of cell migration.

Zhang XA, He B, Zhou B, Liu L.

J Biol Chem. 2003 Jul 18;278(29):27319-28. Epub 2003 May 8.

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