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Lentivirus-mediated RNA interference targeting the long noncoding RNA HOTAIR inhibits proliferation and invasion of endometrial carcinoma cells in vitro and in vivo.

Huang J, Ke P, Guo L, Wang W, Tan H, Liang Y, Yao S.

Int J Gynecol Cancer. 2014 May;24(4):635-42. doi: 10.1097/IGC.0000000000000121.


HOTAIR, a cell cycle-associated long noncoding RNA and a strong predictor of survival, is preferentially expressed in classical and mesenchymal glioma.

Zhang JX, Han L, Bao ZS, Wang YY, Chen LY, Yan W, Yu SZ, Pu PY, Liu N, You YP, Jiang T, Kang CS; Chinese Glioma Cooperative Group.

Neuro Oncol. 2013 Dec;15(12):1595-603. doi: 10.1093/neuonc/not131. Epub 2013 Nov 7.


The long non-coding RNA HOTAIR indicates a poor prognosis and promotes metastasis in non-small cell lung cancer.

Liu XH, Liu ZL, Sun M, Liu J, Wang ZX, De W.

BMC Cancer. 2013 Oct 8;13:464. doi: 10.1186/1471-2407-13-464.


Long non-coding RNA HOTAIR, a driver of malignancy, predicts negative prognosis and exhibits oncogenic activity in oesophageal squamous cell carcinoma.

Li X, Wu Z, Mei Q, Li X, Guo M, Fu X, Han W.

Br J Cancer. 2013 Oct 15;109(8):2266-78. doi: 10.1038/bjc.2013.548. Epub 2013 Sep 10.


MicroRNA-199a-3p regulates endometrial cancer cell proliferation by targeting mammalian target of rapamycin (mTOR).

Wu D, Huang HJ, He CN, Wang KY.

Int J Gynecol Cancer. 2013 Sep;23(7):1191-7. doi: 10.1097/IGC.0b013e31829ea779.


Overexpression of long noncoding RNA, NEAT1 promotes cell proliferation, invasion and migration in endometrial endometrioid adenocarcinoma.

Li Z, Wei D, Yang C, Sun H, Lu T, Kuang D.

Biomed Pharmacother. 2016 Dec;84:244-251. doi: 10.1016/j.biopha.2016.09.008. Epub 2016 Sep 21.


Metastasis-associated long non-coding RNA drives gastric cancer development and promotes peritoneal metastasis.

Okugawa Y, Toiyama Y, Hur K, Toden S, Saigusa S, Tanaka K, Inoue Y, Mohri Y, Kusunoki M, Boland CR, Goel A.

Carcinogenesis. 2014 Dec;35(12):2731-9. doi: 10.1093/carcin/bgu200. Epub 2014 Oct 3.


Silencing of long noncoding RNA MALAT1 by miR-101 and miR-217 inhibits proliferation, migration, and invasion of esophageal squamous cell carcinoma cells.

Wang X, Li M, Wang Z, Han S, Tang X, Ge Y, Zhou L, Zhou C, Yuan Q, Yang M.

J Biol Chem. 2015 Feb 13;290(7):3925-35. doi: 10.1074/jbc.M114.596866. Epub 2014 Dec 23.


Lnc RNA HOTAIR functions as a competing endogenous RNA to regulate HER2 expression by sponging miR-331-3p in gastric cancer.

Liu XH, Sun M, Nie FQ, Ge YB, Zhang EB, Yin DD, Kong R, Xia R, Lu KH, Li JH, De W, Wang KM, Wang ZX.

Mol Cancer. 2014 Apr 28;13:92. doi: 10.1186/1476-4598-13-92.


Inhibitory effect of upregulated DR-nm23 expression on invasion and metastasis in colorectal cancer.

Qu L, Liang L, Su J, Yang Z.

Eur J Cancer Prev. 2013 Nov;22(6):512-22. doi: 10.1097/CEJ.0b013e328361625d.


Inhibition of enhancer of zeste homolog 2 (EZH2) expression is associated with decreased tumor cell proliferation, migration, and invasion in endometrial cancer cell lines.

Eskander RN, Ji T, Huynh B, Wardeh R, Randall LM, Hoang B.

Int J Gynecol Cancer. 2013 Jul;23(6):997-1005. doi: 10.1097/IGC.0b013e318296a265.


Long non-coding RNA HOTAIR promotes cell migration and invasion via down-regulation of RNA binding motif protein 38 in hepatocellular carcinoma cells.

Ding C, Cheng S, Yang Z, Lv Z, Xiao H, Du C, Peng C, Xie H, Zhou L, Wu J, Zheng S.

Int J Mol Sci. 2014 Mar 6;15(3):4060-76. doi: 10.3390/ijms15034060.


TESTIN suppresses tumor growth and invasion via manipulating cell cycle progression in endometrial carcinoma.

Gu Z, Ding G, Liang K, Zhang H, Guo G, Zhang L, Cui J.

Med Sci Monit. 2014 Jun 14;20:980-7. doi: 10.12659/MSM.890544.


Long non-coding RNA HOTAIR promotes carcinogenesis and invasion of gastric adenocarcinoma.

Lee NK, Lee JH, Park CH, Yu D, Lee YC, Cheong JH, Noh SH, Lee SK.

Biochem Biophys Res Commun. 2014 Aug 22;451(2):171-8. doi: 10.1016/j.bbrc.2014.07.067. Epub 2014 Jul 22.


Inhibition of CXCR4 and CXCR7 for reduction of cell proliferation and invasion in human endometrial cancer.

Long P, Sun F, Ma Y, Huang Y.

Tumour Biol. 2016 Jun;37(6):7473-80. doi: 10.1007/s13277-015-4580-y. Epub 2015 Dec 17.


Targeting HOTAIR Induces Mitochondria Related Apoptosis and Inhibits Tumor Growth in Head and Neck Squamous Cell Carcinoma in vitro and in vivo.

Kong L, Zhou X, Wu Y, Wang Y, Chen L, Li P, Liu S, Sun S, Ren Y, Mei M, Wang X, Zhang L.

Curr Mol Med. 2015;15(10):952-60.


Nidogen 1 and Nuclear Protein 1: novel targets of ETV5 transcription factor involved in endometrial cancer invasion.

Pedrola N, Devis L, Llauradó M, Campoy I, Martinez-Garcia E, Garcia M, Muinelo-Romay L, Alonso-Alconada L, Abal M, Alameda F, Mancebo G, Carreras R, Castellví J, Cabrera S, Gil-Moreno A, Matias-Guiu X, Iovanna JL, Colas E, Reventós J, Ruiz A.

Clin Exp Metastasis. 2015 Jun;32(5):467-78. doi: 10.1007/s10585-015-9720-7. Epub 2015 Apr 30.


Large noncoding RNA HOTAIR enhances aggressive biological behavior and is associated with short disease-free survival in human non-small cell lung cancer.

Nakagawa T, Endo H, Yokoyama M, Abe J, Tamai K, Tanaka N, Sato I, Takahashi S, Kondo T, Satoh K.

Biochem Biophys Res Commun. 2013 Jun 28;436(2):319-24. doi: 10.1016/j.bbrc.2013.05.101. Epub 2013 Jun 4.


The long non-coding RNA HOTAIR is upregulated in endometrial carcinoma and correlates with poor prognosis.

He X, Bao W, Li X, Chen Z, Che Q, Wang H, Wan XP.

Int J Mol Med. 2014 Feb;33(2):325-32. doi: 10.3892/ijmm.2013.1570. Epub 2013 Nov 27.


Expression and clinical significance of HMGB1 in human liver cancer: Knockdown inhibits tumor growth and metastasis in vitro and in vivo.

Dong YD, Cui L, Peng CH, Cheng DF, Han BS, Huang F.

Oncol Rep. 2013 Jan;29(1):87-94. doi: 10.3892/or.2012.2070. Epub 2012 Oct 4.


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