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Items: 1 to 20 of 107

1.

Modulation of STAT3 folding and function by TRiC/CCT chaperonin.

Kasembeli M, Lau WC, Roh SH, Eckols TK, Frydman J, Chiu W, Tweardy DJ.

PLoS Biol. 2014 Apr 22;12(4):e1001844. doi: 10.1371/journal.pbio.1001844. eCollection 2014 Apr.

2.

The cytosolic chaperonin CCT/TRiC and cancer cell proliferation.

Boudiaf-Benmammar C, Cresteil T, Melki R.

PLoS One. 2013 Apr 16;8(4):e60895. doi: 10.1371/journal.pone.0060895. Print 2013.

3.
4.

Folding of large multidomain proteins by partial encapsulation in the chaperonin TRiC/CCT.

Rüßmann F, Stemp MJ, Mönkemeyer L, Etchells SA, Bracher A, Hartl FU.

Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21208-15. doi: 10.1073/pnas.1218836109. Epub 2012 Nov 28.

5.

The Hsp70 and TRiC/CCT chaperone systems cooperate in vivo to assemble the von Hippel-Lindau tumor suppressor complex.

Melville MW, McClellan AJ, Meyer AS, Darveau A, Frydman J.

Mol Cell Biol. 2003 May;23(9):3141-51.

6.

The structural basis of substrate recognition by the eukaryotic chaperonin TRiC/CCT.

Joachimiak LA, Walzthoeni T, Liu CW, Aebersold R, Frydman J.

Cell. 2014 Nov 20;159(5):1042-1055. doi: 10.1016/j.cell.2014.10.042.

7.

The molecular chaperone TRiC/CCT binds to the Trp-Asp 40 (WD40) repeat protein WDR68 and promotes its folding, protein kinase DYRK1A binding, and nuclear accumulation.

Miyata Y, Shibata T, Aoshima M, Tsubata T, Nishida E.

J Biol Chem. 2014 Nov 28;289(48):33320-32. doi: 10.1074/jbc.M114.586115. Epub 2014 Oct 22.

9.

A gradient of ATP affinities generates an asymmetric power stroke driving the chaperonin TRIC/CCT folding cycle.

Reissmann S, Joachimiak LA, Chen B, Meyer AS, Nguyen A, Frydman J.

Cell Rep. 2012 Oct 25;2(4):866-77. doi: 10.1016/j.celrep.2012.08.036. Epub 2012 Oct 4.

10.

Overexpression of chaperonin containing TCP1, subunit 3 predicts poor prognosis in hepatocellular carcinoma.

Cui X, Hu ZP, Li Z, Gao PJ, Zhu JY.

World J Gastroenterol. 2015 Jul 28;21(28):8588-604. doi: 10.3748/wjg.v21.i28.8588.

11.

Interactions of subunit CCT3 in the yeast chaperonin CCT/TRiC with Q/N-rich proteins revealed by high-throughput microscopy analysis.

Nadler-Holly M, Breker M, Gruber R, Azia A, Gymrek M, Eisenstein M, Willison KR, Schuldiner M, Horovitz A.

Proc Natl Acad Sci U S A. 2012 Nov 13;109(46):18833-8. doi: 10.1073/pnas.1209277109. Epub 2012 Oct 29.

12.

Cytosolic chaperonin protects folding intermediates of Gbeta from aggregation by recognizing hydrophobic beta-strands.

Kubota S, Kubota H, Nagata K.

Proc Natl Acad Sci U S A. 2006 May 30;103(22):8360-5. Epub 2006 May 22.

13.

Contribution of the Type II Chaperonin, TRiC/CCT, to Oncogenesis.

Roh SH, Kasembeli M, Bakthavatsalam D, Chiu W, Tweardy DJ.

Int J Mol Sci. 2015 Nov 6;16(11):26706-20. doi: 10.3390/ijms161125975. Review.

14.

The molecular architecture of the eukaryotic chaperonin TRiC/CCT.

Leitner A, Joachimiak LA, Bracher A, Mönkemeyer L, Walzthoeni T, Chen B, Pechmann S, Holmes S, Cong Y, Ma B, Ludtke S, Chiu W, Hartl FU, Aebersold R, Frydman J.

Structure. 2012 May 9;20(5):814-25. doi: 10.1016/j.str.2012.03.007. Epub 2012 Apr 12.

15.

Vaccinia-related kinase 2 mediates accumulation of polyglutamine aggregates via negative regulation of the chaperonin TRiC.

Kim S, Park DY, Lee D, Kim W, Jeong YH, Lee J, Chung SK, Ha H, Choi BH, Kim KT.

Mol Cell Biol. 2014 Feb;34(4):643-52. doi: 10.1128/MCB.00756-13. Epub 2013 Dec 2.

16.

The CCT/TRiC chaperonin is required for maturation of sphingosine kinase 1.

Zebol JR, Hewitt NM, Moretti PA, Lynn HE, Lake JA, Li P, Vadas MA, Wattenberg BW, Pitson SM.

Int J Biochem Cell Biol. 2009 Apr;41(4):822-7. doi: 10.1016/j.biocel.2008.08.012. Epub 2008 Aug 14.

17.

Chaperonin TRiC/CCT Recognizes Fusion Oncoprotein AML1-ETO through Subunit-Specific Interactions.

Roh SH, Kasembeli MM, Galaz-Montoya JG, Chiu W, Tweardy DJ.

Biophys J. 2016 Jun 7;110(11):2377-2385. doi: 10.1016/j.bpj.2016.04.045.

18.

Tumorigenic mutations in VHL disrupt folding in vivo by interfering with chaperonin binding.

Feldman DE, Spiess C, Howard DE, Frydman J.

Mol Cell. 2003 Nov;12(5):1213-24.

19.

Vaccinia-Related Kinase 2 Controls the Stability of the Eukaryotic Chaperonin TRiC/CCT by Inhibiting the Deubiquitinating Enzyme USP25.

Kim S, Lee D, Lee J, Song H, Kim HJ, Kim KT.

Mol Cell Biol. 2015 May;35(10):1754-62. doi: 10.1128/MCB.01325-14. Epub 2015 Mar 9.

20.

Formation of the VHL-elongin BC tumor suppressor complex is mediated by the chaperonin TRiC.

Feldman DE, Thulasiraman V, Ferreyra RG, Frydman J.

Mol Cell. 1999 Dec;4(6):1051-61.

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