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Enhanced Anti-Cancer Effect of Snake Venom Activated NK Cells on Lung Cancer Cells by Inactivation of NF-κB.

Kollipara PS, Won do H, Hwang CJ, Jung YY, Yoon HS, Park MH, Song MJ, Song HS, Hong JT.

Biomol Ther (Seoul). 2014 Feb;22(2):106-13. doi: 10.4062/biomolther.2013.103.


Co-culture with NK-92MI cells enhanced the anti-cancer effect of bee venom on NSCLC cells by inactivation of NF-κB.

Kollipara PS, Kim JH, Won D, Lee SM, Sung HC, Chang HS, Lee KT, Lee KS, Park MH, Song MJ, Song HS, Hong JT.

Arch Pharm Res. 2014 Mar;37(3):379-89. doi: 10.1007/s12272-013-0319-8. Epub 2014 Jan 1.


Cell growth inhibition and induction of apoptosis by snake venom toxin in ovarian cancer cell via inactivation of nuclear factor κB and signal transducer and activator of transcription 3.

Song JK, Jo MR, Park MH, Song HS, An BJ, Song MJ, Han SB, Hong JT.

Arch Pharm Res. 2012 May;35(5):867-76. doi: 10.1007/s12272-012-0512-1. Epub 2012 May 29.


Inhibitory effect of snake venom toxin on NF-κB activity prevents human cervical cancer cell growth via increase of death receptor 3 and 5 expression.

Lee HL, Park MH, Hong JE, Kim DH, Kim JY, Seo HO, Han SB, Yoon JH, Lee WH, Song HS, Lee JI, Lee US, Song MJ, Hong JT.

Arch Toxicol. 2016 Feb;90(2):463-77. doi: 10.1007/s00204-014-1393-5. Epub 2014 Nov 23.


Cancer cell growth inhibitory effect of bee venom via increase of death receptor 3 expression and inactivation of NF-kappa B in NSCLC cells.

Choi KE, Hwang CJ, Gu SM, Park MH, Kim JH, Park JH, Ahn YJ, Kim JY, Song MJ, Song HS, Han SB, Hong JT.

Toxins (Basel). 2014 Jul 25;6(8):2210-28. doi: 10.3390/toxins6082210.


Anti-cancer effect of tectochrysin in NSCLC cells through overexpression of death receptor and inactivation of STAT3.

Oh SB, Hwang CJ, Song SY, Jung YY, Yun HM, Sok CH, Sung HC, Yi JM, Park DH, Ham YW, Han SB, Hwang BY, Hong JT.

Cancer Lett. 2014 Oct 10;353(1):95-103. doi: 10.1016/j.canlet.2014.07.007. Epub 2014 Jul 30.


Anti-cancer effect of bee venom on colon cancer cell growth by activation of death receptors and inhibition of nuclear factor kappa B.

Zheng J, Lee HL, Ham YW, Song HS, Song MJ, Hong JT.

Oncotarget. 2015 Dec 29;6(42):44437-51. doi: 10.18632/oncotarget.6295.


Anti-cancer effect of bee venom in prostate cancer cells through activation of caspase pathway via inactivation of NF-κB.

Park MH, Choi MS, Kwak DH, Oh KW, Yoon DY, Han SB, Song HS, Song MJ, Hong JT.

Prostate. 2011 Jun 1;71(8):801-12. doi: 10.1002/pros.21296. Epub 2010 Nov 17.


Anti-cancer effect of snake venom toxin through down regulation of AP-1 mediated PRDX6 expression.

Lee HL, Park MH, Son DJ, Song HS, Kim JH, Ko SC, Song MJ, Lee WH, Yoon JH, Ham YW, Han SB, Hong JT.

Oncotarget. 2015 Sep 8;6(26):22139-51.


Snake venom toxin from Vipera lebetina turanica induces apoptosis of colon cancer cells via upregulation of ROS- and JNK-mediated death receptor expression.

Park MH, Jo M, Won D, Song HS, Han SB, Song MJ, Hong JT.

BMC Cancer. 2012 Jun 8;12:228. doi: 10.1186/1471-2407-12-228.


Anti-cancer effect of bee venom toxin and melittin in ovarian cancer cells through induction of death receptors and inhibition of JAK2/STAT3 pathway.

Jo M, Park MH, Kollipara PS, An BJ, Song HS, Han SB, Kim JH, Song MJ, Hong JT.

Toxicol Appl Pharmacol. 2012 Jan 1;258(1):72-81. doi: 10.1016/j.taap.2011.10.009. Epub 2011 Oct 15.


Enhanced cell growth inhibition by thiacremonone in paclitaxel-treated lung cancer cells.

Ban JO, Hwang CJ, Park MH, Hwang IK, Jeong HS, Lee HP, Hyun BK, Kim JY, Youn HS, Ham YW, Yoon DY, Han SB, Song MJ, Hong JT.

Arch Pharm Res. 2015 Jul;38(7):1351-62. doi: 10.1007/s12272-015-0589-4. Epub 2015 Mar 20.


Bee venom inhibits growth of human cervical tumors in mice.

Lee HL, Park SH, Kim TM, Jung YY, Park MH, Oh SH, Yun HS, Jun HO, Yoo HS, Han SB, Lee US, Yoon JH, Song MJ, Hong JT.

Oncotarget. 2015 Mar 30;6(9):7280-92.


Interleukin-32 enhances cytotoxic effect of natural killer cells to cancer cells via activation of death receptor 3.

Park MH, Song MJ, Cho MC, Moon DC, Yoon DY, Han SB, Hong JT.

Immunology. 2012 Jan;135(1):63-72. doi: 10.1111/j.1365-2567.2011.03513.x.


Gambogic acid synergistically potentiates cisplatin-induced apoptosis in non-small-cell lung cancer through suppressing NF-κB and MAPK/HO-1 signalling.

Wang LH, Li Y, Yang SN, Wang FY, Hou Y, Cui W, Chen K, Cao Q, Wang S, Zhang TY, Wang ZZ, Xiao W, Yang JY, Wu CF.

Br J Cancer. 2014 Jan 21;110(2):341-52. doi: 10.1038/bjc.2013.752. Epub 2013 Dec 3.


Therapeutic efficacy and molecular mechanisms of snake (Walterinnesia aegyptia) venom-loaded silica nanoparticles in the treatment of breast cancer- and prostate cancer-bearing experimental mouse models.

Badr G, Al-Sadoon MK, Rabah DM.

Free Radic Biol Med. 2013 Dec;65:175-89. doi: 10.1016/j.freeradbiomed.2013.06.018. Epub 2013 Jun 27.


Snake venom toxin inhibits cell growth through induction of apoptosis in neuroblastoma cells.

Park MH, Son DJ, Kwak DH, Song HS, Oh KW, Yoo HS, Lee YM, Song MJ, Hong JT.

Arch Pharm Res. 2009 Nov;32(11):1545-54. doi: 10.1007/s12272-009-2106-0.


Transfection of chimeric anti-CD138 gene enhances natural killer cell activation and killing of multiple myeloma cells.

Jiang H, Zhang W, Shang P, Zhang H, Fu W, Ye F, Zeng T, Huang H, Zhang X, Sun W, Man-Yuen Sze D, Yi Q, Hou J.

Mol Oncol. 2014 Mar;8(2):297-310. doi: 10.1016/j.molonc.2013.12.001. Epub 2013 Dec 12.

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