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Items: 1 to 20 of 103

1.

Engineering class I cytochrome P450 by gene fusion with NADPH-dependent reductase and S. avermitilis host development for daidzein biotransformation.

Choi KY, Jung E, Yun H, Yang YH, Kim BG.

Appl Microbiol Biotechnol. 2014 Oct;98(19):8191-200. doi: 10.1007/s00253-014-5706-7. Epub 2014 Apr 22.

PMID:
24752838
2.

Engineering of daidzein 3'-hydroxylase P450 enzyme into catalytically self-sufficient cytochrome P450.

Choi KY, Jung E, Jung DH, An BR, Pandey BP, Yun H, Sung C, Park HY, Kim BG.

Microb Cell Fact. 2012 Jun 14;11:81. doi: 10.1186/1475-2859-11-81.

3.

Cloning, expression and characterization of CYP102D1, a self-sufficient P450 monooxygenase from Streptomyces avermitilis.

Choi KY, Jung E, Jung DH, Pandey BP, Yun H, Park HY, Kazlauskas RJ, Kim BG.

FEBS J. 2012 May;279(9):1650-62. doi: 10.1111/j.1742-4658.2011.08462.x. Epub 2012 Jan 23.

4.

Coexpression of genetically engineered fused enzyme between yeast NADPH-P450 reductase and human cytochrome P450 3A4 and human cytochrome b5 in yeast.

Hayashi K, Sakaki T, Kominami S, Inouye K, Yabusaki Y.

Arch Biochem Biophys. 2000 Sep 1;381(1):164-70.

PMID:
11019832
5.

Regioselectivity-driven evolution of CYP102D1 for improved synthesis of 3'-ortho-dihydroxyisoflavone.

Choi KY, Yang YH, Kim BG.

Enzyme Microb Technol. 2015 Apr;71:20-7. doi: 10.1016/j.enzmictec.2015.01.004. Epub 2015 Jan 25.

PMID:
25765306
6.

Novel iron-sulfur containing NADPH-reductase from Nocardia farcinica IFM10152 and fusion construction with CYP51 lanosterol demethylase.

Choi KY, Jung EO, Jung DH, Pandey BP, Lee N, Yun H, Park HY, Kim BG.

Biotechnol Bioeng. 2012 Mar;109(3):630-6. doi: 10.1002/bit.24359. Epub 2011 Nov 13.

PMID:
22038382
8.
9.

Regioselective hydroxylation of daidzein using P450 (CYP105D7) from Streptomyces avermitilis MA4680.

Pandey BP, Roh C, Choi KY, Lee N, Kim EJ, Ko S, Kim T, Yun H, Kim BG.

Biotechnol Bioeng. 2010 Mar 1;105(4):697-704. doi: 10.1002/bit.22582.

PMID:
19845003
10.
11.

Biochemical characterization of rat P450 2C11 fused to rat or bacterial NADPH-P450 reductase domains.

Helvig C, Capdevila JH.

Biochemistry. 2000 May 2;39(17):5196-205.

PMID:
10819987
12.

A-ring ortho-specific monohydroxylation of daidzein by cytochrome P450s of Nocardia farcinica IFM10152.

Choi KY, Kim TJ, Koh SK, Roh CH, Pandey BP, Lee N, Kim BG.

Biotechnol J. 2009 Nov;4(11):1586-95. doi: 10.1002/biot.200900157.

PMID:
19918785
13.

P450BM-3; a tale of two domains--or is it three?

Peterson JA, Sevrioukova I, Truan G, Graham-Lorence SE.

Steroids. 1997 Jan;62(1):117-23. Review.

PMID:
9029725
14.

Switching pyridine nucleotide specificity in P450 BM3: mechanistic analysis of the W1046H and W1046A enzymes.

Neeli R, Roitel O, Scrutton NS, Munro AW.

J Biol Chem. 2005 May 6;280(18):17634-44. Epub 2005 Feb 14.

15.

Catalytically functional flavocytochrome chimeras of P450 BM3 and nitric oxide synthase.

Fuziwara S, Sagami I, Rozhkova E, Craig D, Noble MA, Munro AW, Chapman SK, Shimizu T.

J Inorg Biochem. 2002 Sep 20;91(4):515-26.

PMID:
12237219
16.

Biotransformation of isoflavone using enzymatic reactions.

Roh C.

Molecules. 2013 Mar 6;18(3):3028-40. doi: 10.3390/molecules18033028.

17.

Regioselective hydroxylation of isoflavones by Streptomyces avermitilis MA-4680.

Roh C, Seo SH, Choi KY, Cha M, Pandey BP, Kim JH, Park JS, Kim DH, Chang IS, Kim BG.

J Biosci Bioeng. 2009 Jul;108(1):41-6. doi: 10.1016/j.jbiosc.2009.02.021.

PMID:
19577190
18.

Improved NADPH Regeneration for Fungal Cytochrome P450 Monooxygenase by Co-Expressing Bacterial Glucose Dehydrogenase in Resting-Cell Biotransformation of Recombinant Yeast.

Jeon H, Durairaj P, Lee D, Ahsan MM, Yun H.

J Microbiol Biotechnol. 2016 Dec 28;26(12):2076-2086. doi: 10.4014/jmb.1605.05090.

19.

Production of a novel O-methyl-isoflavone by regioselective sequential hydroxylation and O-methylation reactions in Streptomyces avermitilis host system.

Choi KY, Jung E, Yang YH, Kim BG.

Biotechnol Bioeng. 2013 Oct;110(10):2591-9. doi: 10.1002/bit.24931. Epub 2013 Apr 26.

PMID:
23592181
20.

In vitro metabolism of terfenadine by a purified recombinant fusion protein containing cytochrome P4503A4 and NADPH-P450 reductase. Comparison to human liver microsomes and precision-cut liver tissue slices.

Rodrigues AD, Mulford DJ, Lee RD, Surber BW, Kukulka MJ, Ferrero JL, Thomas SB, Shet MS, Estabrook RW.

Drug Metab Dispos. 1995 Jul;23(7):765-75.

PMID:
7587966

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