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Items: 1 to 20 of 234

1.

LL-202, a newly synthesized flavonoid, inhibits tumor growth via inducing G(2)/M phase arrest and cell apoptosis in MCF-7 human breast cancer cells in vitro and in vivo.

Tao L, Fu R, Wang X, Yao J, Zhou Y, Dai Q, Li Z, Lu N, Wang W.

Toxicol Lett. 2014 Jul 3;228(1):1-12. doi: 10.1016/j.toxlet.2014.04.002.

PMID:
24752227
2.

Magnolol induces apoptosis in MCF-7 human breast cancer cells through G2/M phase arrest and caspase-independent pathway.

Zhou Y, Bi Y, Yang C, Yang J, Jiang Y, Meng F, Yu B, Khan M, Ma T, Yang H.

Pharmazie. 2013 Sep;68(9):755-62.

PMID:
24147344
3.

A novel synthetic 2-(3-methoxyphenyl)-6,7-methylenedioxoquinolin-4-one arrests the G2/M phase arrest via Cdc25c and induces apoptosis through caspase- and mitochondria-dependent pathways in TSGH8301 human bladder cancer cells.

Hsu SC, Yu CC, Yang JS, Lai KC, Wu SH, Lin JJ, Kuo JH, Yang ST, Huang CC, Kuo SC, Chung JG.

Int J Oncol. 2012 Mar;40(3):731-8. doi: 10.3892/ijo.2011.1241.

PMID:
22021033
4.

LW-214, a newly synthesized flavonoid, induces intrinsic apoptosis pathway by down-regulating Trx-1 in MCF-7 human breast cells.

Pan D, Li W, Miao H, Yao J, Li Z, Wei L, Zhao L, Guo Q.

Biochem Pharmacol. 2014 Feb 15;87(4):598-610. doi: 10.1016/j.bcp.2013.12.010.

PMID:
24374359
5.

GL-V9, a newly synthetic flavonoid derivative, induces mitochondrial-mediated apoptosis and G2/M cell cycle arrest in human hepatocellular carcinoma HepG2 cells.

Li L, Lu N, Dai Q, Wei L, Zhao Q, Li Z, He Q, Dai Y, Guo Q.

Eur J Pharmacol. 2011 Nov 16;670(1):13-21. doi: 10.1016/j.ejphar.2011.08.054.

PMID:
21944925
6.

NCPMF-60 induces G2/M cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells.

Dai QS, Liu W, Wang XB, Lu N, Gong DD, Kong LY, Guo QL.

Anticancer Drugs. 2011 Jan;22(1):46-57. doi: 10.1097/CAD.0b013e3283405801.

PMID:
20948430
7.
8.

LYG-202 exerts antitumor effect on PI3K/Akt signaling pathway in human breast cancer cells.

Zhao Y, Wang X, Sun Y, Zhou Y, Yin Y, Ding Y, Li Z, Guo Q, Lu N.

Apoptosis. 2015 Sep;20(9):1253-69. doi: 10.1007/s10495-015-1145-x.

PMID:
26153346
9.

Cantharidin induces G2/M phase arrest and apoptosis in human colorectal cancer colo 205 cells through inhibition of CDK1 activity and caspase-dependent signaling pathways.

Huang WW, Ko SW, Tsai HY, Chung JG, Chiang JH, Chen KT, Chen YC, Chen HY, Chen YF, Yang JS.

Int J Oncol. 2011 Apr;38(4):1067-73. doi: 10.3892/ijo.2011.922.

PMID:
21271215
10.

Benzyl isothiocyanate (BITC) induces G2/M phase arrest and apoptosis in human melanoma A375.S2 cells through reactive oxygen species (ROS) and both mitochondria-dependent and death receptor-mediated multiple signaling pathways.

Huang SH, Wu LW, Huang AC, Yu CC, Lien JC, Huang YP, Yang JS, Yang JH, Hsiao YP, Wood WG, Yu CS, Chung JG.

J Agric Food Chem. 2012 Jan 18;60(2):665-75. doi: 10.1021/jf204193v.

PMID:
22148415
11.

Apoptotic death in curcumin-treated NPC-TW 076 human nasopharyngeal carcinoma cells is mediated through the ROS, mitochondrial depolarization and caspase-3-dependent signaling responses.

Kuo CL, Wu SY, Ip SW, Wu PP, Yu CS, Yang JS, Chen PY, Wu SH, Chung JG.

Int J Oncol. 2011 Aug;39(2):319-28. doi: 10.3892/ijo.2011.1057.

PMID:
21617861
13.

Aminoflavone induces oxidative DNA damage and reactive oxidative species-mediated apoptosis in breast cancer cells.

McLean L, Soto U, Agama K, Francis J, Jimenez R, Pommier Y, Sowers L, Brantley E.

Int J Cancer. 2008 Apr 1;122(7):1665-74.

16.

Antineoplastic effects of α-santalol on estrogen receptor-positive and estrogen receptor-negative breast cancer cells through cell cycle arrest at G2/M phase and induction of apoptosis.

Santha S, Bommareddy A, Rule B, Guillermo R, Kaushik RS, Young A, Dwivedi C.

PLoS One. 2013;8(2):e56982. doi: 10.1371/journal.pone.0056982. Erratum in: PLoS One. 2013;8(6). doi:10.1371/annotation/c732480c-eb97-4eff-acb6-300797f4efa9.

17.
18.

Phenethyl isothiocyanate (PEITC) promotes G2/M phase arrest via p53 expression and induces apoptosis through caspase- and mitochondria-dependent signaling pathways in human prostate cancer DU 145 cells.

Tang NY, Huang YT, Yu CS, Ko YC, Wu SH, Ji BC, Yang JS, Yang JL, Hsia TC, Chen YY, Chung JG.

Anticancer Res. 2011 May;31(5):1691-702.

PMID:
21617228
19.

The novel synthesized 2-(3-(methylamino)phenyl)-6-(pyrrolidin-1-yl)quinolin-4-one (Smh-3) compound induces G2/M phase arrest and mitochondrial-dependent apoptotic cell death through inhibition of CDK1 and AKT activity in HL-60 human leukemia cells.

Huang SM, Yang JS, Tsai SC, Chen MH, Hsu MH, Lin HY, Chou LC, Chinag JH, Lee KH, Huang LJ, Kuo SC.

Int J Oncol. 2011 May;38(5):1357-64. doi: 10.3892/ijo.2011.952.

PMID:
21344160
20.

Ridaifen-SB8, a novel tamoxifen derivative, induces apoptosis via reactive oxygen species-dependent signaling pathway.

Guo WZ, Shiina I, Wang Y, Umeda E, Watanabe C, Uetake S, Ohashi Y, Yamori T, Dan S.

Biochem Pharmacol. 2013 Nov 1;86(9):1272-84. doi: 10.1016/j.bcp.2013.08.020.

PMID:
23973528
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