Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 123

1.

Zinc transporter 8 (ZnT8) and β cell function.

Davidson HW, Wenzlau JM, O'Brien RM.

Trends Endocrinol Metab. 2014 Aug;25(8):415-24. doi: 10.1016/j.tem.2014.03.008. Epub 2014 Apr 18. Review.

2.

Combined Deletion of Slc30a7 and Slc30a8 Unmasks a Critical Role for ZnT8 in Glucose-Stimulated Insulin Secretion.

Syring KE, Boortz KA, Oeser JK, Ustione A, Platt KA, Shadoan MK, McGuinness OP, Piston DW, Powell DR, O'Brien RM.

Endocrinology. 2016 Dec;157(12):4534-4541. Epub 2016 Oct 18.

3.

Molecular Genetic Regulation of Slc30a8/ZnT8 Reveals a Positive Association With Glucose Tolerance.

Mitchell RK, Hu M, Chabosseau PL, Cane MC, Meur G, Bellomo EA, Carzaniga R, Collinson LM, Li WH, Hodson DJ, Rutter GA.

Mol Endocrinol. 2016 Jan;30(1):77-91. doi: 10.1210/me.2015-1227. Epub 2015 Nov 19.

4.

Hypoxia lowers SLC30A8/ZnT8 expression and free cytosolic Zn2+ in pancreatic beta cells.

Gerber PA, Bellomo EA, Hodson DJ, Meur G, Solomou A, Mitchell RK, Hollinshead M, Chimienti F, Bosco D, Hughes SJ, Johnson PR, Rutter GA.

Diabetologia. 2014 Aug;57(8):1635-44. doi: 10.1007/s00125-014-3266-0. Epub 2014 May 28.

5.

Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants.

Nicolson TJ, Bellomo EA, Wijesekara N, Loder MK, Baldwin JM, Gyulkhandanyan AV, Koshkin V, Tarasov AI, Carzaniga R, Kronenberger K, Taneja TK, da Silva Xavier G, Libert S, Froguel P, Scharfmann R, Stetsyuk V, Ravassard P, Parker H, Gribble FM, Reimann F, Sladek R, Hughes SJ, Johnson PR, Masseboeuf M, Burcelin R, Baldwin SA, Liu M, Lara-Lemus R, Arvan P, Schuit FC, Wheeler MB, Chimienti F, Rutter GA.

Diabetes. 2009 Sep;58(9):2070-83. doi: 10.2337/db09-0551. Epub 2009 Jun 19.

6.

Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion.

Wijesekara N, Dai FF, Hardy AB, Giglou PR, Bhattacharjee A, Koshkin V, Chimienti F, Gaisano HY, Rutter GA, Wheeler MB.

Diabetologia. 2010 Aug;53(8):1656-68. doi: 10.1007/s00125-010-1733-9. Epub 2010 Apr 28.

PMID:
20424817
7.

Different role of zinc transporter 8 between type 1 diabetes mellitus and type 2 diabetes mellitus.

Yi B, Huang G, Zhou Z.

J Diabetes Investig. 2016 Jul;7(4):459-65. doi: 10.1111/jdi.12441. Epub 2016 Jan 9. Review.

8.

Zinc and diabetes.

Chabosseau P, Rutter GA.

Arch Biochem Biophys. 2016 Dec 1;611:79-85. doi: 10.1016/j.abb.2016.05.022. Epub 2016 Jun 1. Review.

9.

The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearance.

Tamaki M, Fujitani Y, Hara A, Uchida T, Tamura Y, Takeno K, Kawaguchi M, Watanabe T, Ogihara T, Fukunaka A, Shimizu T, Mita T, Kanazawa A, Imaizumi MO, Abe T, Kiyonari H, Hojyo S, Fukada T, Kawauchi T, Nagamatsu S, Hirano T, Kawamori R, Watada H.

J Clin Invest. 2013 Oct;123(10):4513-24. doi: 10.1172/JCI68807. Epub 2013 Sep 24.

10.

Zinc, a regulator of islet function and glucose homeostasis.

Wijesekara N, Chimienti F, Wheeler MB.

Diabetes Obes Metab. 2009 Nov;11 Suppl 4:202-14. doi: 10.1111/j.1463-1326.2009.01110.x. Review.

PMID:
19817803
11.

Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice.

Lemaire K, Ravier MA, Schraenen A, Creemers JW, Van de Plas R, Granvik M, Van Lommel L, Waelkens E, Chimienti F, Rutter GA, Gilon P, in't Veld PA, Schuit FC.

Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):14872-7. doi: 10.1073/pnas.0906587106. Epub 2009 Aug 18.

12.

Zinc, zinc transporters and diabetes.

Rungby J.

Diabetologia. 2010 Aug;53(8):1549-51. doi: 10.1007/s00125-010-1793-x. Epub 2010 May 21.

PMID:
20490449
13.

The Zinc Transporter Slc30a8/ZnT8 Is Required in a Subpopulation of Pancreatic α-Cells for Hypoglycemia-induced Glucagon Secretion.

Solomou A, Meur G, Bellomo E, Hodson DJ, Tomas A, Li SM, Philippe E, Herrera PL, Magnan C, Rutter GA.

J Biol Chem. 2015 Aug 28;290(35):21432-42. doi: 10.1074/jbc.M115.645291. Epub 2015 Jul 15.

14.

Coupling of Insulin Secretion and Display of a Granule-resident Zinc Transporter ZnT8 on the Surface of Pancreatic Beta Cells.

Huang Q, Merriman C, Zhang H, Fu D.

J Biol Chem. 2017 Mar 10;292(10):4034-4043. doi: 10.1074/jbc.M116.772152. Epub 2017 Jan 27.

15.

In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion.

Chimienti F, Devergnas S, Pattou F, Schuit F, Garcia-Cuenca R, Vandewalle B, Kerr-Conte J, Van Lommel L, Grunwald D, Favier A, Seve M.

J Cell Sci. 2006 Oct 15;119(Pt 20):4199-206. Epub 2006 Sep 19.

16.

Down-regulation of ZnT8 expression in INS-1 rat pancreatic beta cells reduces insulin content and glucose-inducible insulin secretion.

Fu Y, Tian W, Pratt EB, Dirling LB, Shyng SL, Meshul CK, Cohen DM.

PLoS One. 2009 May 25;4(5):e5679. doi: 10.1371/journal.pone.0005679.

17.

The Role of Oxidative Stress and Hypoxia in Pancreatic Beta-Cell Dysfunction in Diabetes Mellitus.

Gerber PA, Rutter GA.

Antioxid Redox Signal. 2017 Apr 1;26(10):501-518. doi: 10.1089/ars.2016.6755. Epub 2016 Jun 30. Review.

18.

Lipid-tuned Zinc Transport Activity of Human ZnT8 Protein Correlates with Risk for Type-2 Diabetes.

Merriman C, Huang Q, Rutter GA, Fu D.

J Biol Chem. 2016 Dec 30;291(53):26950-26957. doi: 10.1074/jbc.M116.764605. Epub 2016 Nov 8.

19.

Downregulation of ZnT8 expression in pancreatic β-cells of diabetic mice.

Tamaki M, Fujitani Y, Uchida T, Hirose T, Kawamori R, Watada H.

Islets. 2009 Sep-Oct;1(2):124-8. doi: 10.4161/isl.1.2.9433.

PMID:
21099260
20.

The zinc transporter ZnT8 (slc30A8) is expressed exclusively in beta cells in porcine islets.

Schweiger M, Steffl M, Amselgruber WM.

Histochem Cell Biol. 2013 Dec;140(6):677-84. doi: 10.1007/s00418-013-1137-2. Epub 2013 Sep 13.

PMID:
24029898

Supplemental Content

Support Center