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Items: 1 to 20 of 142

1.

High-fat diet increases tau expression in the brain of T2DM and AD mice independently of peripheral metabolic status.

Takalo M, Haapasalo A, Martiskainen H, Kurkinen KM, Koivisto H, Miettinen P, Khandelwal VK, Kemppainen S, Kaminska D, Mäkinen P, Leinonen V, Pihlajamäki J, Soininen H, Laakso M, Tanila H, Hiltunen M.

J Nutr Biochem. 2014 Jun;25(6):634-41. doi: 10.1016/j.jnutbio.2014.02.003. Epub 2014 Mar 12.

PMID:
24746833
2.

Increased expression of three-repeat isoforms of tau contributes to tau pathology in a rat model of chronic type 2 diabetes.

Jung HJ, Park SS, Mok JO, Lee TK, Park CS, Park SA.

Exp Neurol. 2011 Apr;228(2):232-41. doi: 10.1016/j.expneurol.2011.01.012. Epub 2011 Jan 31.

PMID:
21281635
3.

Detrimental effects of diet-induced obesity on τ pathology are independent of insulin resistance in τ transgenic mice.

Leboucher A, Laurent C, Fernandez-Gomez FJ, Burnouf S, Troquier L, Eddarkaoui S, Demeyer D, Caillierez R, Zommer N, Vallez E, Bantubungi K, Breton C, Pigny P, Buée-Scherrer V, Staels B, Hamdane M, Tailleux A, Buée L, Blum D.

Diabetes. 2013 May;62(5):1681-8. doi: 10.2337/db12-0866. Epub 2012 Dec 18.

4.

The ε3 and ε4 alleles of human APOE differentially affect tau phosphorylation in hyperinsulinemic and pioglitazone treated mice.

To AW, Ribe EM, Chuang TT, Schroeder JE, Lovestone S.

PLoS One. 2011 Feb 10;6(2):e16991. doi: 10.1371/journal.pone.0016991.

5.

Agmatine ameliorates type 2 diabetes induced-Alzheimer's disease-like alterations in high-fat diet-fed mice via reactivation of blunted insulin signalling.

Kang S, Kim CH, Jung H, Kim E, Song HT, Lee JE.

Neuropharmacology. 2017 Feb;113(Pt A):467-479. doi: 10.1016/j.neuropharm.2016.10.029. Epub 2016 Oct 31.

6.

Intranasal insulin ameliorates tau hyperphosphorylation in a rat model of type 2 diabetes.

Yang Y, Ma D, Wang Y, Jiang T, Hu S, Zhang M, Yu X, Gong CX.

J Alzheimers Dis. 2013;33(2):329-38. doi: 10.3233/JAD-2012-121294.

PMID:
22936005
7.

Contribution of genetic and dietary insulin resistance to Alzheimer phenotype in APP/PS1 transgenic mice.

Hiltunen M, Khandelwal VK, Yaluri N, Tiilikainen T, Tusa M, Koivisto H, Krzisch M, Vepsäläinen S, Mäkinen P, Kemppainen S, Miettinen P, Haapasalo A, Soininen H, Laakso M, Tanila H.

J Cell Mol Med. 2012 Jun;16(6):1206-22. doi: 10.1111/j.1582-4934.2011.01384.x.

8.

Chronic peripheral hyperinsulinemia has no substantial influence on tau phosphorylation in vivo.

Becker K, Freude S, Zemva J, Stöhr O, Krone W, Schubert M.

Neurosci Lett. 2012 May 16;516(2):306-10. doi: 10.1016/j.neulet.2012.04.022. Epub 2012 Apr 12.

PMID:
22521314
9.

Sex-specific effects of high fat diet on indices of metabolic syndrome in 3xTg-AD mice: implications for Alzheimer's disease.

Barron AM, Rosario ER, Elteriefi R, Pike CJ.

PLoS One. 2013 Oct 28;8(10):e78554. doi: 10.1371/journal.pone.0078554. eCollection 2013.

10.

High-fat diet aggravates amyloid-beta and tau pathologies in the 3xTg-AD mouse model.

Julien C, Tremblay C, Phivilay A, Berthiaume L, Emond V, Julien P, Calon F.

Neurobiol Aging. 2010 Sep;31(9):1516-31. doi: 10.1016/j.neurobiolaging.2008.08.022. Epub 2008 Oct 15.

PMID:
18926603
11.

Subcutaneous administration of liraglutide ameliorates Alzheimer-associated tau hyperphosphorylation in rats with type 2 diabetes.

Yang Y, Zhang J, Ma D, Zhang M, Hu S, Shao S, Gong CX.

J Alzheimers Dis. 2013;37(3):637-48. doi: 10.3233/JAD-130491.

PMID:
23948890
12.

Chronic temporal lobe epilepsy is associated with enhanced Alzheimer-like neuropathology in 3×Tg-AD mice.

Yan XX, Cai Y, Shelton J, Deng SH, Luo XG, Oddo S, Laferla FM, Cai H, Rose GM, Patrylo PR.

PLoS One. 2012;7(11):e48782. doi: 10.1371/journal.pone.0048782. Epub 2012 Nov 14.

13.

Brain Insulin Signaling Is Increased in Insulin-Resistant States and Decreases in FOXOs and PGC-1α and Increases in Aβ1-40/42 and Phospho-Tau May Abet Alzheimer Development.

Sajan M, Hansen B, Ivey R 3rd, Sajan J, Ari C, Song S, Braun U, Leitges M, Farese-Higgs M, Farese RV.

Diabetes. 2016 Jul;65(7):1892-903. doi: 10.2337/db15-1428. Epub 2016 Feb 19.

14.

Limited Alzheimer-type neurodegeneration in experimental obesity and type 2 diabetes mellitus.

Moroz N, Tong M, Longato L, Xu H, de la Monte SM.

J Alzheimers Dis. 2008 Sep;15(1):29-44.

PMID:
18780965
15.

Leptin restores the insulinotropic effect of exenatide in a mouse model of type 2 diabetes with increased adiposity induced by streptozotocin and high-fat diet.

Sakai T, Kusakabe T, Ebihara K, Aotani D, Yamamoto-Kataoka S, Zhao M, Gumbilai VM, Ebihara C, Aizawa-Abe M, Yamamoto Y, Noguchi M, Fujikura J, Hosoda K, Inagaki N, Nakao K.

Am J Physiol Endocrinol Metab. 2014 Oct 15;307(8):E712-9. doi: 10.1152/ajpendo.00272.2014. Epub 2014 Aug 26.

PMID:
25159327
16.

Effect of high-fat diet on cognitive impairment in triple-transgenic mice model of Alzheimer's disease.

Sah SK, Lee C, Jang JH, Park GH.

Biochem Biophys Res Commun. 2017 Nov 4;493(1):731-736. doi: 10.1016/j.bbrc.2017.08.122. Epub 2017 Sep 1.

PMID:
28865961
17.

High-fat diet-induced memory impairment in triple-transgenic Alzheimer's disease (3xTgAD) mice is independent of changes in amyloid and tau pathology.

Knight EM, Martins IV, Gümüsgöz S, Allan SM, Lawrence CB.

Neurobiol Aging. 2014 Aug;35(8):1821-32. doi: 10.1016/j.neurobiolaging.2014.02.010. Epub 2014 Feb 15.

18.

Ursodeoxycholic acid improves insulin sensitivity and hepatic steatosis by inducing the excretion of hepatic lipids in high-fat diet-fed KK-Ay mice.

Tsuchida T, Shiraishi M, Ohta T, Sakai K, Ishii S.

Metabolism. 2012 Jul;61(7):944-53. doi: 10.1016/j.metabol.2011.10.023. Epub 2011 Dec 7.

PMID:
22154323
19.

Abnormal serine phosphorylation of insulin receptor substrate 1 is associated with tau pathology in Alzheimer's disease and tauopathies.

Yarchoan M, Toledo JB, Lee EB, Arvanitakis Z, Kazi H, Han LY, Louneva N, Lee VM, Kim SF, Trojanowski JQ, Arnold SE.

Acta Neuropathol. 2014 Nov;128(5):679-89. doi: 10.1007/s00401-014-1328-5. Epub 2014 Aug 9.

20.

Experimental induction of type 2 diabetes in aging-accelerated mice triggered Alzheimer-like pathology and memory deficits.

Mehla J, Chauhan BC, Chauhan NB.

J Alzheimers Dis. 2014;39(1):145-62. doi: 10.3233/JAD-131238.

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