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Items: 1 to 20 of 221

1.

L1CAM promotes enrichment of immunosuppressive T cells in human pancreatic cancer correlating with malignant progression.

Grage-Griebenow E, Jerg E, Gorys A, Wicklein D, Wesch D, Freitag-Wolf S, Goebel L, Vogel I, Becker T, Ebsen M, Röcken C, Altevogt P, Schumacher U, Schäfer H, Sebens S.

Mol Oncol. 2014 Jul;8(5):982-97. doi: 10.1016/j.molonc.2014.03.001. Epub 2014 Apr 2.

2.

CD4+ T cells potently induce epithelial-mesenchymal-transition in premalignant and malignant pancreatic ductal epithelial cells-novel implications of CD4+ T cells in pancreatic cancer development.

Goebel L, Grage-Griebenow E, Gorys A, Helm O, Genrich G, Lenk L, Wesch D, Ungefroren H, Freitag-Wolf S, Sipos B, Röcken C, Schäfer H, Sebens S.

Oncoimmunology. 2015 Jan 22;4(4):e1000083. eCollection 2015 Apr.

3.

Up-regulation of L1CAM in pancreatic duct cells is transforming growth factor beta1- and slug-dependent: role in malignant transformation of pancreatic cancer.

Geismann C, Morscheck M, Koch D, Bergmann F, Ungefroren H, Arlt A, Tsao MS, Bachem MG, Altevogt P, Sipos B, Fölsch UR, Schäfer H, Müerköster SS.

Cancer Res. 2009 May 15;69(10):4517-26. doi: 10.1158/0008-5472.CAN-08-3493. Epub 2009 May 12.

4.

Comparative characterization of stroma cells and ductal epithelium in chronic pancreatitis and pancreatic ductal adenocarcinoma.

Helm O, Mennrich R, Petrick D, Goebel L, Freitag-Wolf S, Röder C, Kalthoff H, Röcken C, Sipos B, Kabelitz D, Schäfer H, Oberg HH, Wesch D, Sebens S.

PLoS One. 2014 May 5;9(5):e94357. doi: 10.1371/journal.pone.0094357. eCollection 2014.

5.

Myofibroblast-induced tumorigenicity of pancreatic ductal epithelial cells is L1CAM dependent.

Schäfer H, Geismann C, Heneweer C, Egberts JH, Korniienko O, Kiefel H, Moldenhauer G, Bachem MG, Kalthoff H, Altevogt P, Sebens S.

Carcinogenesis. 2012 Jan;33(1):84-93. doi: 10.1093/carcin/bgr262. Epub 2011 Nov 17.

PMID:
22095073
6.

Monitoring and functional characterization of the lymphocytic compartment in pancreatic ductal adenocarcinoma patients.

Oberg HH, Grage-Griebenow E, Adam-Klages S, Jerg E, Peipp M, Kellner C, Petrick D, Gonnermann D, Freitag-Wolf S, Röcken C, Sebens T, Vogel I, Becker T, Ebsen M, Kabelitz D, Wesch D, Sebens S.

Pancreatology. 2016 Nov - Dec;16(6):1069-1079. doi: 10.1016/j.pan.2016.07.008. Epub 2016 Jul 11.

PMID:
27424476
7.

Binding of the transcription factor Slug to the L1CAM promoter is essential for transforming growth factor-β1 (TGF-β)-induced L1CAM expression in human pancreatic ductal adenocarcinoma cells.

Geismann C, Arlt A, Bauer I, Pfeifer M, Schirmer U, Altevogt P, Müerköster SS, Schäfer H.

Int J Oncol. 2011 Jan;38(1):257-66.

PMID:
21109948
8.

alpha5-integrin is crucial for L1CAM-mediated chemoresistance in pancreatic adenocarcinoma.

Sebens Müerköster S, Kötteritzsch J, Geismann C, Gast D, Kruse ML, Altevogt P, Fölsch UR, Schäfer H.

Int J Oncol. 2009 Jan;34(1):243-53.

PMID:
19082495
9.

The fatal alliance of cancer and T cells: How pancreatic tumor cells gather immunosuppressive T cells.

Grage-Griebenow E, Schäfer H, Sebens S.

Oncoimmunology. 2014 Jun 25;3:e29382. eCollection 2014.

10.
11.

Drug-induced expression of the cellular adhesion molecule L1CAM confers anti-apoptotic protection and chemoresistance in pancreatic ductal adenocarcinoma cells.

Sebens Müerköster S, Werbing V, Sipos B, Debus MA, Witt M, Grossmann M, Leisner D, Kötteritzsch J, Kappes H, Klöppel G, Altevogt P, Fölsch UR, Schäfer H.

Oncogene. 2007 Apr 26;26(19):2759-68. Epub 2006 Nov 6.

PMID:
17086212
12.

An increased abundance of tumor-infiltrating regulatory T cells is correlated with the progression and prognosis of pancreatic ductal adenocarcinoma.

Tang Y, Xu X, Guo S, Zhang C, Tang Y, Tian Y, Ni B, Lu B, Wang H.

PLoS One. 2014 Mar 17;9(3):e91551. doi: 10.1371/journal.pone.0091551. eCollection 2014.

13.

Elevated L1CAM expression in precursor lesions and primary and metastastic tissues of pancreatic ductal adenocarcinoma.

Bergmann F, Wandschneider F, Sipos B, Moldenhauer G, Schniewind B, Welsch T, Schirrmacher P, Klöppel G, Altevogt P, Schäfer H, Sebens Müerköster S.

Oncol Rep. 2010 Oct;24(4):909-15.

PMID:
20811670
14.

L1 Cell adhesion molecule (L1CAM) expression at the cancer invasive front is a novel prognostic marker of pancreatic ductal adenocarcinoma.

Tsutsumi S, Morohashi S, Kudo Y, Akasaka H, Ogasawara H, Ono M, Takasugi K, Ishido K, Hakamada K, Kijima H.

J Surg Oncol. 2011 Jun 1;103(7):669-73. doi: 10.1002/jso.21880. Epub 2011 Feb 28.

PMID:
21360711
15.

L1CAM-integrin interaction induces constitutive NF-kappaB activation in pancreatic adenocarcinoma cells by enhancing IL-1beta expression.

Kiefel H, Bondong S, Erbe-Hoffmann N, Hazin J, Riedle S, Wolf J, Pfeifer M, Arlt A, Schäfer H, Müerköster SS, Altevogt P.

Oncogene. 2010 Aug 26;29(34):4766-78. doi: 10.1038/onc.2010.230. Epub 2010 Jun 14.

PMID:
20543863
16.

Tumor-associated macrophages exhibit pro- and anti-inflammatory properties by which they impact on pancreatic tumorigenesis.

Helm O, Held-Feindt J, Grage-Griebenow E, Reiling N, Ungefroren H, Vogel I, Krüger U, Becker T, Ebsen M, Röcken C, Kabelitz D, Schäfer H, Sebens S.

Int J Cancer. 2014 Aug 15;135(4):843-61. doi: 10.1002/ijc.28736. Epub 2014 Feb 5.

17.

High Expression of Human Leukocyte Antigen-G is Associated with a Poor Prognosis in Patients with PDAC.

Xu YF, Lu Y, Cheng H, Jiang J, Xu J, Long J, Liu L, Ni Q, Liu C, Yu XJ.

Curr Mol Med. 2015;15(4):360-7.

PMID:
25829020
18.

Low intratumoral regulatory T cells and high peritumoral CD8(+) T cells relate to long-term survival in patients with pancreatic ductal adenocarcinoma after pancreatectomy.

Liu L, Zhao G, Wu W, Rong Y, Jin D, Wang D, Lou W, Qin X.

Cancer Immunol Immunother. 2016 Jan;65(1):73-82. doi: 10.1007/s00262-015-1775-4. Epub 2015 Dec 8.

PMID:
26646849
19.

Expansion and de novo generation of potentially therapeutic regulatory T cells in patients with autoimmune hepatitis.

Longhi MS, Meda F, Wang P, Samyn M, Mieli-Vergani G, Vergani D, Ma Y.

Hepatology. 2008 Feb;47(2):581-91. doi: 10.1002/hep.22071.

PMID:
18220288
20.

A gene expression signature of epithelial tubulogenesis and a role for ASPM in pancreatic tumor progression.

Wang WY, Hsu CC, Wang TY, Li CR, Hou YC, Chu JM, Lee CT, Liu MS, Su JJ, Jian KY, Huang SS, Jiang SS, Shan YS, Lin PW, Shen YY, Lee MT, Chan TS, Chang CC, Chen CH, Chang IS, Lee YL, Chen LT, Tsai KK.

Gastroenterology. 2013 Nov;145(5):1110-20. doi: 10.1053/j.gastro.2013.07.040. Epub 2013 Jul 27.

PMID:
23896173

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