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Items: 1 to 20 of 108

1.

Jun kinase-induced overexpression of leukemia-associated Rho GEF (LARG) mediates sustained hypercontraction of longitudinal smooth muscle in inflammation.

Al-Shboul O, Nalli AD, Kumar DP, Zhou R, Mahavadi S, Kuemmerle JF, Grider JR, Murthy KS.

Am J Physiol Cell Physiol. 2014 Jun 15;306(12):C1129-41. doi: 10.1152/ajpcell.00021.2014. Epub 2014 Apr 16.

2.

Hypercontractility of intestinal longitudinal smooth muscle induced by cytokines is mediated by the nuclear factor-κB/AMP-activated kinase/myosin light chain kinase pathway.

Nalli AD, Kumar DP, Mahavadi S, Al-Shboul O, Alkahtani R, Kuemmerle JF, Grider JR, Murthy KS.

J Pharmacol Exp Ther. 2014 Jul;350(1):89-98. doi: 10.1124/jpet.113.212522. Epub 2014 Apr 25.

3.

Upregulation of RGS4 and downregulation of CPI-17 mediate inhibition of colonic muscle contraction by interleukin-1beta.

Hu W, Mahavadi S, Li F, Murthy KS.

Am J Physiol Cell Physiol. 2007 Dec;293(6):C1991-2000. Epub 2007 Oct 24.

4.

Role of Ca2+-sensitization in attenuated carbachol-induced contraction of the colon in a rat model of colitis.

Al-Jarallah A, Khan I, Oriowo MA.

Eur J Pharmacol. 2008 Jan 28;579(1-3):365-73. Epub 2007 Nov 1.

PMID:
18037403
7.

Cytokine-induced iNOS and ERK1/2 inhibit adenylyl cyclase type 5/6 activity and stimulate phosphodiesterase 4D5 activity in intestinal longitudinal smooth muscle.

Mahavadi S, Nalli AD, Kumar DP, Hu W, Kuemmerle JF, Grider JR, Murthy KS.

Am J Physiol Cell Physiol. 2014 Aug 15;307(4):C402-11. doi: 10.1152/ajpcell.00123.2014. Epub 2014 Jun 18.

8.

Myosin light chain kinase activation and calcium sensitization in smooth muscle in vivo.

Mizuno Y, Isotani E, Huang J, Ding H, Stull JT, Kamm KE.

Am J Physiol Cell Physiol. 2008 Aug;295(2):C358-64. doi: 10.1152/ajpcell.90645.2007. Epub 2008 Jun 4.

9.

Signaling pathways mediating gastrointestinal smooth muscle contraction and MLC20 phosphorylation by motilin receptors.

Huang J, Zhou H, Mahavadi S, Sriwai W, Lyall V, Murthy KS.

Am J Physiol Gastrointest Liver Physiol. 2005 Jan;288(1):G23-31.

10.

Increased PDE5 activity and decreased Rho kinase and PKC activities in colonic muscle from caveolin-1-/- mice impair the peristaltic reflex and propulsion.

Mahavadi S, Bhattacharya S, Kumar DP, Clay C, Ross G, Akbarali HI, Grider JR, Murthy KS.

Am J Physiol Gastrointest Liver Physiol. 2013 Dec;305(12):G964-74. doi: 10.1152/ajpgi.00165.2013. Epub 2013 Oct 24.

11.

Immune/Inflammatory Response and Hypocontractility of Rabbit Colonic Smooth Muscle After TNBS-Induced Colitis.

Zhang Y, Li F, Wang H, Yin C, Huang J, Mahavadi S, Murthy KS, Hu W.

Dig Dis Sci. 2016 Jul;61(7):1925-40. doi: 10.1007/s10620-016-4078-5. Epub 2016 Feb 15.

12.

Role of TNF-alpha in muscularis inflammation and motility disorder in a TNBS-induced colitis model: clues from TNF-alpha-deficient mice.

Kinoshita K, Hori M, Fujisawa M, Sato K, Ohama T, Momotani E, Ozaki H.

Neurogastroenterol Motil. 2006 Jul;18(7):578-88.

PMID:
16771773
13.

Characterization of protein kinase pathways responsible for Ca2+ sensitization in rat ileal longitudinal smooth muscle.

Ihara E, Moffat L, Ostrander J, Walsh MP, MacDonald JA.

Am J Physiol Gastrointest Liver Physiol. 2007 Oct;293(4):G699-710. Epub 2007 Jul 26.

14.

ERK and p38MAPK pathways regulate myosin light chain phosphatase and contribute to Ca2+ sensitization of intestinal smooth muscle contraction.

Ihara E, Yu Q, Chappellaz M, MacDonald JA.

Neurogastroenterol Motil. 2015 Jan;27(1):135-46. doi: 10.1111/nmo.12491.

PMID:
25557225
15.

Gq/G13 signaling by ET-1 in smooth muscle: MYPT1 phosphorylation via ETA and CPI-17 dephosphorylation via ETB.

Hersch E, Huang J, Grider JR, Murthy KS.

Am J Physiol Cell Physiol. 2004 Nov;287(5):C1209-18.

16.

The contribution of protein kinase C and CPI-17 signaling pathways to hypercontractility in murine experimental colitis.

Ihara E, Chappellaz M, Turner SR, MacDonald JA.

Neurogastroenterol Motil. 2012 Jan;24(1):e15-26. doi: 10.1111/j.1365-2982.2011.01821.x. Epub 2011 Nov 16.

PMID:
22093175
17.

Carbachol-induced rabbit bladder smooth muscle contraction: roles of protein kinase C and Rho kinase.

Wang T, Kendig DM, Smolock EM, Moreland RS.

Am J Physiol Renal Physiol. 2009 Dec;297(6):F1534-42. doi: 10.1152/ajprenal.00095.2009. Epub 2009 Sep 30.

18.

Inflammatory gene expression by human colonic smooth muscle cells.

Salinthone S, Singer CA, Gerthoffer WT.

Am J Physiol Gastrointest Liver Physiol. 2004 Sep;287(3):G627-37. Epub 2004 Apr 29.

19.

Role of various kinases in muscarinic M3 receptor-mediated contraction of longitudinal muscle of rat colon.

Anderson CD Jr, Kendig DM, Al-Qudah M, Mahavadi S, Murthy KS, Grider JR.

J Smooth Muscle Res. 2014;50:103-19. doi: 10.1540/jsmr.50.103.

20.

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