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Varenicline, low dose naltrexone, and their combination for heavy-drinking smokers: human laboratory findings.

Ray LA, Courtney KE, Ghahremani DG, Miotto K, Brody A, London ED.

Psychopharmacology (Berl). 2014 Oct;231(19):3843-53. doi: 10.1007/s00213-014-3519-0. Epub 2014 Apr 15.


Varenicline, naltrexone, and their combination for heavy-drinking smokers: preliminary neuroimaging findings.

Ray LA, Courtney KE, Ghahremani DG, Miotto K, Brody A, London ED.

Am J Drug Alcohol Abuse. 2015 Jan;41(1):35-44. doi: 10.3109/00952990.2014.927881. Epub 2014 Jun 20.


Combined varenicline and naltrexone treatment reduces smoking topography intensity in heavy-drinking smokers.

Roche DJ, Bujarski S, Hartwell E, Green R, Ray LA.

Pharmacol Biochem Behav. 2015 Jul;134:92-8. doi: 10.1016/j.pbb.2015.04.013. Epub 2015 Apr 28.


A preliminary investigation of varenicline for heavy drinking smokers.

Fucito LM, Toll BA, Wu R, Romano DM, Tek E, O'Malley SS.

Psychopharmacology (Berl). 2011 Jun;215(4):655-63. doi: 10.1007/s00213-010-2160-9. Epub 2011 Jan 11.


Varenicline decreases alcohol consumption in heavy-drinking smokers.

Mitchell JM, Teague CH, Kayser AS, Bartlett SE, Fields HL.

Psychopharmacology (Berl). 2012 Oct;223(3):299-306. doi: 10.1007/s00213-012-2717-x. Epub 2012 May 1.


An open-label pilot trial of N-acetylcysteine and varenicline in adult cigarette smokers.

McClure EA, Baker NL, Gipson CD, Carpenter MJ, Roper AP, Froeliger BE, Kalivas PW, Gray KM.

Am J Drug Alcohol Abuse. 2015 Jan;41(1):52-6. doi: 10.3109/00952990.2014.933839. Epub 2014 Jul 25.


Combination varenicline and bupropion SR for tobacco-dependence treatment in cigarette smokers: a randomized trial.

Ebbert JO, Hatsukami DK, Croghan IT, Schroeder DR, Allen SS, Hays JT, Hurt RD.

JAMA. 2014 Jan 8;311(2):155-63. doi: 10.1001/jama.2013.283185.


The effects of varenicline on stress-induced and cue-induced craving for cigarettes.

Ray LA, Lunny K, Bujarski S, Moallem N, Krull JL, Miotto K.

Drug Alcohol Depend. 2013 Jul 1;131(1-2):136-42. doi: 10.1016/j.drugalcdep.2012.12.015. Epub 2013 Jan 5.


Combining varenicline and nicotine patches: a randomized controlled trial study in smoking cessation.

Ramon JM, Morchon S, Baena A, Masuet-Aumatell C.

BMC Med. 2014 Oct 8;12:172. doi: 10.1186/s12916-014-0172-8.


Combining Varenicline (Chantix) with Naltrexone Decreases Alcohol Drinking More Effectively Than Does Either Drug Alone in a Rodent Model of Alcoholism.

Froehlich JC, Fischer SM, Dilley JE, Nicholson ER, Smith TN, Filosa NJ, Rademacher LC.

Alcohol Clin Exp Res. 2016 Sep;40(9):1961-70. doi: 10.1111/acer.13157. Epub 2016 Jul 29.


Efficacy of varenicline to prompt quit attempts in smokers not currently trying to quit: a randomized placebo-controlled trial.

Hughes JR, Rennard SI, Fingar JR, Talbot SK, Callas PW, Fagerstrom KO.

Nicotine Tob Res. 2011 Oct;13(10):955-64. doi: 10.1093/ntr/ntr103. Epub 2011 Jun 7.


Increasing varenicline dose in smokers who do not respond to the standard dosage: a randomized clinical trial.

Hajek P, McRobbie H, Myers Smith K, Phillips A, Cornwall D, Dhanji AR.

JAMA Intern Med. 2015 Feb;175(2):266-71. doi: 10.1001/jamainternmed.2014.6916. Erratum in: JAMA Intern Med. 2016 Jan;176(1):143.


Varenicline reduces alcohol self-administration in heavy-drinking smokers.

McKee SA, Harrison EL, O'Malley SS, Krishnan-Sarin S, Shi J, Tetrault JM, Picciotto MR, Petrakis IL, Estevez N, Balchunas E.

Biol Psychiatry. 2009 Jul 15;66(2):185-90. doi: 10.1016/j.biopsych.2009.01.029. Epub 2009 Feb 27.


Effects of Varenicline Alone and in Combination With Low-dose Naltrexone on Alcohol-primed Smoking in Heavy-drinking Tobacco Users: A Preliminary Laboratory Study.

Roberts W, Shi JM, Tetrault JM, McKee SA.

J Addict Med. 2018 Feb 12. doi: 10.1097/ADM.0000000000000392. [Epub ahead of print]


Varenicline effects on drinking, craving and neural reward processing among non-treatment-seeking alcohol-dependent individuals.

Schacht JP, Anton RF, Randall PK, Li X, Henderson S, Myrick H.

Psychopharmacology (Berl). 2014 Sep;231(18):3799-807. doi: 10.1007/s00213-014-3518-1. Epub 2014 Mar 20.


Pharmacokinetic-pharmacodynamic modeling of the effect of varenicline on nicotine craving in adult smokers.

Ravva P, Gastonguay MR, Faessel HM, Lee TC, Niaura R.

Nicotine Tob Res. 2015 Jan;17(1):106-13. doi: 10.1093/ntr/ntu154. Epub 2014 Aug 21.


Varenicline for smoking cessation in bipolar disorder: a randomized, double-blind, placebo-controlled study.

Chengappa KN, Perkins KA, Brar JS, Schlicht PJ, Turkin SR, Hetrick ML, Levine MD, George TP.

J Clin Psychiatry. 2014 Jul;75(7):765-72. doi: 10.4088/JCP.13m08756.


Naltrexone improves quit rates, attenuates smoking urge, and reduces alcohol use in heavy drinking smokers attempting to quit smoking.

Fridberg DJ, Cao D, Grant JE, King AC.

Alcohol Clin Exp Res. 2014 Oct;38(10):2622-9. doi: 10.1111/acer.12513. Epub 2014 Oct 21.


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