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Items: 1 to 20 of 173

1.

Upregulation of tumor necrosis factor α and ADAMTS-5, but not ADAMTS-4, in human intervertebral cartilage endplate with modic changes.

Chen S, Huang Y, Zhou ZJ, Hu ZJ, Wang JY, Xu WB, Fang XQ, Fan SW.

Spine (Phila Pa 1976). 2014 Jun 15;39(14):E817-25. doi: 10.1097/BRS.0000000000000362.

PMID:
24732836
3.

TNF-α and IL-1β promote a disintegrin-like and metalloprotease with thrombospondin type I motif-5-mediated aggrecan degradation through syndecan-4 in intervertebral disc.

Wang J, Markova D, Anderson DG, Zheng Z, Shapiro IM, Risbud MV.

J Biol Chem. 2011 Nov 18;286(46):39738-49. doi: 10.1074/jbc.M111.264549. Epub 2011 Sep 23.

4.

Tumor necrosis factor-immunoreactive cells and PGP 9.5-immunoreactive nerve fibers in vertebral endplates of patients with discogenic low back Pain and Modic Type 1 or Type 2 changes on MRI.

Ohtori S, Inoue G, Ito T, Koshi T, Ozawa T, Doya H, Saito T, Moriya H, Takahashi K.

Spine (Phila Pa 1976). 2006 Apr 20;31(9):1026-31.

PMID:
16641780
5.

Expression of ADAMTS-4 (aggrecanase-1) and possible involvement in regression of lumbar disc herniation.

Hatano E, Fujita T, Ueda Y, Okuda T, Katsuda S, Okada Y, Matsumoto T.

Spine (Phila Pa 1976). 2006 Jun 1;31(13):1426-32.

PMID:
16741450
6.

Tumor necrosis factor-α induces ADAMTS-4 expression in human osteoarthritis chondrocytes.

Xue J, Wang J, Liu Q, Luo A.

Mol Med Rep. 2013 Dec;8(6):1755-60. doi: 10.3892/mmr.2013.1729. Epub 2013 Oct 14.

PMID:
24126638
7.

Inflammatory cytokines associated with degenerative disc disease control aggrecanase-1 (ADAMTS-4) expression in nucleus pulposus cells through MAPK and NF-κB.

Tian Y, Yuan W, Fujita N, Wang J, Wang H, Shapiro IM, Risbud MV.

Am J Pathol. 2013 Jun;182(6):2310-21. doi: 10.1016/j.ajpath.2013.02.037. Epub 2013 Apr 17.

8.

Aggrecan degradation in human articular cartilage explants is mediated by both ADAMTS-4 and ADAMTS-5.

Song RH, Tortorella MD, Malfait AM, Alston JT, Yang Z, Arner EC, Griggs DW.

Arthritis Rheum. 2007 Feb;56(2):575-85.

9.

Mechanical destabilization induced by controlled annular incision of the intervertebral disc dysregulates metalloproteinase expression and induces disc degeneration.

Melrose J, Shu C, Young C, Ho R, Smith MM, Young AA, Smith SS, Gooden B, Dart A, Podadera J, Appleyard RC, Little CB.

Spine (Phila Pa 1976). 2012 Jan 1;37(1):18-25. doi: 10.1097/BRS.0b013e31820cd8d5.

PMID:
22179320
10.

Protein kinase Czeta is up-regulated in osteoarthritic cartilage and is required for activation of NF-kappaB by tumor necrosis factor and interleukin-1 in articular chondrocytes.

LaVallie ER, Chockalingam PS, Collins-Racie LA, Freeman BA, Keohan CC, Leitges M, Dorner AJ, Morris EA, Majumdar MK, Arai M.

J Biol Chem. 2006 Aug 25;281(34):24124-37. Epub 2006 Jun 23.

11.

Negative effects of ADAMTS-7 and ADAMTS-12 on endplate cartilage differentiation.

Zhang Q, Huang M, Wang X, Xu X, Ni M, Wang Y.

J Orthop Res. 2012 Aug;30(8):1238-43. doi: 10.1002/jor.22069. Epub 2012 Jan 13.

12.

SOX9 is a regulator of ADAMTSs-induced cartilage degeneration at the early stage of human osteoarthritis.

Zhang Q, Ji Q, Wang X, Kang L, Fu Y, Yin Y, Li Z, Liu Y, Xu X, Wang Y.

Osteoarthritis Cartilage. 2015 Dec;23(12):2259-68. doi: 10.1016/j.joca.2015.06.014. Epub 2015 Jul 8.

13.

The NLRP3/Caspase-1/Interleukin-1β Axis Is Active in Human Lumbar Cartilaginous Endplate Degeneration.

Tang P, Zhu R, Ji WP, Wang JY, Chen S, Fan SW, Hu ZJ.

Clin Orthop Relat Res. 2016 Aug;474(8):1818-26. doi: 10.1007/s11999-016-4866-4. Epub 2016 May 4.

14.

Assessment of the matrix degenerative effects of MMP-3, ADAMTS-4, and HTRA1, injected into a bovine intervertebral disc organ culture model.

Furtwängler T, Chan SC, Bahrenberg G, Richards PJ, Gantenbein-Ritter B.

Spine (Phila Pa 1976). 2013 Oct 15;38(22):E1377-87. doi: 10.1097/BRS.0b013e31829ffde8.

PMID:
23778376
15.

Role of aggrecanase 1 in Lyme arthritis.

Behera AK, Hildebrand E, Szafranski J, Hung HH, Grodzinsky AJ, Lafyatis R, Koch AE, Kalish R, Perides G, Steere AC, Hu LT.

Arthritis Rheum. 2006 Oct;54(10):3319-29.

16.

Dual function of β-catenin in articular cartilage growth and degeneration at different stages of postnatal cartilage development.

Ning B, Wang P, Pei X, Kang Y, Song J, Wang D, Zhang W, Ma R.

Int Orthop. 2012 Mar;36(3):655-64. doi: 10.1007/s00264-011-1315-6. Epub 2011 Jul 14.

17.

Leptin induces ADAMTS-4, ADAMTS-5, and ADAMTS-9 genes expression by mitogen-activated protein kinases and NF-ĸB signaling pathways in human chondrocytes.

Yaykasli KO, Hatipoglu OF, Yaykasli E, Yildirim K, Kaya E, Ozsahin M, Uslu M, Gunduz E.

Cell Biol Int. 2015 Jan;39(1):104-12. doi: 10.1002/cbin.10336. Epub 2014 Jul 31.

PMID:
25045124
18.

Aggrecanases and aggrecanase-generated fragments in the human intervertebral disc at early and advanced stages of disc degeneration.

Patel KP, Sandy JD, Akeda K, Miyamoto K, Chujo T, An HS, Masuda K.

Spine (Phila Pa 1976). 2007 Nov 1;32(23):2596-603.

PMID:
17978660
19.

The effect of protease inhibitors on the induction of osteoarthritis-related biomarkers in bovine full-depth cartilage explants.

He Y, Zheng Q, Jiang M, Sun S, Christiansen TG, Kassem M, Karsdal MA, Bay-Jensen AC.

PLoS One. 2015 Apr 24;10(4):e0122700. doi: 10.1371/journal.pone.0122700. eCollection 2015.

20.

Interleukin-6 upregulates expression of ADAMTS-4 in fibroblast-like synoviocytes from patients with rheumatoid arthritis.

Mimata Y, Kamataki A, Oikawa S, Murakami K, Uzuki M, Shimamura T, Sawai T.

Int J Rheum Dis. 2012 Feb;15(1):36-44. doi: 10.1111/j.1756-185X.2011.01656.x. Epub 2011 Sep 14.

PMID:
22324945

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