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Items: 1 to 20 of 102

1.

T cells infiltrate the liver and kill hepatocytes in HLA-B(∗)57:01-associated floxacillin-induced liver injury.

Wuillemin N, Terracciano L, Beltraminelli H, Schlapbach C, Fontana S, Krähenbühl S, Pichler WJ, Yerly D.

Am J Pathol. 2014 Jun;184(6):1677-82. doi: 10.1016/j.ajpath.2014.02.018. Epub 2014 Apr 13.

PMID:
24731753
2.

HLA haplotype determines hapten or p-i T cell reactivity to flucloxacillin.

Wuillemin N, Adam J, Fontana S, Krähenbühl S, Pichler WJ, Yerly D.

J Immunol. 2013 May 15;190(10):4956-64. doi: 10.4049/jimmunol.1202949. Epub 2013 Apr 17.

3.

Human leukocyte antigen (HLA)-B*57:01-restricted activation of drug-specific T cells provides the immunological basis for flucloxacillin-induced liver injury.

Monshi MM, Faulkner L, Gibson A, Jenkins RE, Farrell J, Earnshaw CJ, Alfirevic A, Cederbrant K, Daly AK, French N, Pirmohamed M, Park BK, Naisbitt DJ.

Hepatology. 2013 Feb;57(2):727-39. doi: 10.1002/hep.26077.

PMID:
22987284
4.

Promiscuous T-cell responses to drugs and drug-haptens.

Yaseen FS, Saide K, Kim SH, Monshi M, Tailor A, Wood S, Meng X, Jenkins R, Faulkner L, Daly AK, Pirmohamed M, Park BK, Naisbitt DJ.

J Allergy Clin Immunol. 2015 Aug;136(2):474-6.e8. doi: 10.1016/j.jaci.2015.02.036. Epub 2015 Apr 22. No abstract available.

PMID:
25910715
5.

The safety of flucloxacillin in HIV-infected patients with positive HLA-B*5701 genotype.

Vera JH, Naous N, Mackie N, Winston A, Cooke G.

AIDS. 2013 Jan 28;27(3):484-5. doi: 10.1097/QAD.0b013e32835a9a0d.

PMID:
23032409
6.

Activation of Flucloxacillin-Specific CD8+ T-Cells With the Potential to Promote Hepatocyte Cytotoxicity in a Mouse Model.

Nattrass R, Faulkner L, Vocanson M, Antoine DJ, Kipar A, Kenna G, Nicolas JF, Park BK, Naisbitt DJ.

Toxicol Sci. 2015 Jul;146(1):146-56. doi: 10.1093/toxsci/kfv077. Epub 2015 Apr 14.

PMID:
25877613
7.

HLA-B*5701 and flucloxacillin associated drug-induced liver disease.

Phillips EJ, Mallal SA.

AIDS. 2013 Jan 28;27(3):491-2. doi: 10.1097/QAD.0b013e32835ca9d5. No abstract available.

PMID:
23291545
8.

Pharmacogenomics of severe cutaneous adverse reactions and drug-induced liver injury.

Kaniwa N, Saito Y.

J Hum Genet. 2013 Jun;58(6):317-26. doi: 10.1038/jhg.2013.37. Epub 2013 May 2. Review.

PMID:
23635947
9.

Genetic association studies in drug-induced liver injury.

Daly AK, Day CP.

Semin Liver Dis. 2009 Nov;29(4):400-11. doi: 10.1055/s-0029-1240009. Epub 2009 Oct 13. Review.

PMID:
19826974
10.

Pathology of immune-mediated liver injury.

Dienes HP, Drebber U.

Dig Dis. 2010;28(1):57-62. doi: 10.1159/000282065. Epub 2010 May 7. Review.

PMID:
20460891
11.

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin.

Daly AK, Donaldson PT, Bhatnagar P, Shen Y, Pe'er I, Floratos A, Daly MJ, Goldstein DB, John S, Nelson MR, Graham J, Park BK, Dillon JF, Bernal W, Cordell HJ, Pirmohamed M, Aithal GP, Day CP; DILIGEN Study.; International SAE Consortium..

Nat Genet. 2009 Jul;41(7):816-9. doi: 10.1038/ng.379. Epub 2009 May 31.

PMID:
19483685
12.

Dietary fish oil exacerbates concanavalin A induced hepatitis through promoting hepatocyte apoptosis and altering immune cell populations.

Xia S, Han M, Li X, Cheng L, Qiang Y, Wu S, Zhang M, Xu H, Liu X, Shao Q.

J Toxicol Sci. 2014 Apr;39(2):179-90.

13.

Role of immune reactions in drug-induced liver injury (DILI).

Ju C, Reilly T.

Drug Metab Rev. 2012 Feb;44(1):107-15. doi: 10.3109/03602532.2011.645579. Epub 2012 Jan 12. Review.

PMID:
22235834
14.

Predicting idiosyncratic drug-induced liver injury: some recent advances.

Chen M, Borlak J, Tong W.

Expert Rev Gastroenterol Hepatol. 2014 Sep;8(7):721-3. doi: 10.1586/17474124.2014.922871. Epub 2014 May 23.

PMID:
24857265
15.

Floxacillin-induced cholestatic hepatitis with evidence of lymphocyte sensitization.

Victorino RM, Maria VA, Correia AP, de Moura C.

Arch Intern Med. 1987 May;147(5):987-9.

PMID:
3579450
16.

Metformin aggravates immune-mediated liver injury in mice.

Volarevic V, Misirkic M, Vucicevic L, Paunovic V, Simovic Markovic B, Stojanovic M, Milovanovic M, Jakovljevic V, Micic D, Arsenijevic N, Trajkovic V, Lukic ML.

Arch Toxicol. 2015 Mar;89(3):437-50. doi: 10.1007/s00204-014-1263-1. Epub 2014 Apr 26.

PMID:
24770553
17.

Characterization of effector cells in lymphocytotoxicity to autologous hepatocytes in HBsAg-positive and autoimmune chronic active hepatitis (CAH).

Barnaba V, Levrero M, Franco A, Ruberti G, Musca A, Bonavita MS, Balsano F.

Liver. 1986 Feb;6(1):45-52.

PMID:
3487021
18.

Mouse liver-specific CD8(+) T-cells encounter their cognate antigen and acquire capacity to destroy target hepatocytes.

Chabot S, Fakhfakh A, Béland K, Lamarre A, Oldstone MB, Alvarez F, Djilali-Saiah I.

J Autoimmun. 2013 May;42:19-28. doi: 10.1016/j.jaut.2012.10.002. Epub 2012 Nov 5.

19.

Inter-individual differences in HLA expression can impact the CDC crossmatch.

Hönger G, Krähenbühl N, Dimeloe S, Stern M, Schaub S, Hess C.

Tissue Antigens. 2015 Apr;85(4):260-6. doi: 10.1111/tan.12537.

PMID:
25786570
20.

ANIT toxicity toward mouse hepatocytes in vivo is mediated primarily by neutrophils via CD18.

Kodali P, Wu P, Lahiji PA, Brown EJ, Maher JJ.

Am J Physiol Gastrointest Liver Physiol. 2006 Aug;291(2):G355-63. Epub 2006 Apr 13.

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