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Items: 1 to 20 of 168

1.

Repositioning: the fast track to new anti-malarial medicines?

Lotharius J, Gamo-Benito FJ, Angulo-Barturen I, Clark J, Connelly M, Ferrer-Bazaga S, Parkinson T, Viswanath P, Bandodkar B, Rautela N, Bharath S, Duffy S, Avery VM, Möhrle JJ, Guy RK, Wells T.

Malar J. 2014 Apr 14;13:143. doi: 10.1186/1475-2875-13-143.

2.

Antiplasmodial activity, in vivo pharmacokinetics and anti-malarial efficacy evaluation of hydroxypyridinone hybrids in a mouse model.

Dambuza NS, Smith P, Evans A, Norman J, Taylor D, Andayi A, Egan T, Chibale K, Wiesner L.

Malar J. 2015 Dec 16;14:505. doi: 10.1186/s12936-015-1032-5.

3.

Bioassay-guided isolation and characterization of active antiplasmodial compounds from Murraya koenigii extracts against Plasmodium falciparum and Plasmodium berghei.

Kamaraj C, Rahuman AA, Roopan SM, Bagavan A, Elango G, Zahir AA, Rajakumar G, Jayaseelan C, Santhoshkumar T, Marimuthu S, Kirthi AV.

Parasitol Res. 2014 May;113(5):1657-72. doi: 10.1007/s00436-014-3810-3. Epub 2014 Mar 18.

PMID:
24638906
4.
5.

Compounds from Sorindeia juglandifolia (Anacardiaceae) exhibit potent anti-plasmodial activities in vitro and in vivo.

Kamkumo RG, Ngoutane AM, Tchokouaha LR, Fokou PV, Madiesse EA, Legac J, Kezetas JJ, Lenta BN, Boyom FF, Dimo T, Mbacham WF, Gut J, Rosenthal PJ.

Malar J. 2012 Nov 21;11:382. doi: 10.1186/1475-2875-11-382.

6.

In vitro and in vivo anti-malarial activity of tigecycline, a glycylcycline antibiotic, in combination with chloroquine.

Sahu R, Walker LA, Tekwani BL.

Malar J. 2014 Oct 21;13:414. doi: 10.1186/1475-2875-13-414.

7.

In vitro and in vivo anti-malarial activity of plants from the Brazilian Amazon.

Lima RB, Rocha e Silva LF, Melo MR, Costa JS, Picanço NS, Lima ES, Vasconcellos MC, Boleti AP, Santos JM, Amorim RC, Chaves FC, Coutinho JP, Tadei WP, Krettli AU, Pohlit AM.

Malar J. 2015 Dec 18;14:508. doi: 10.1186/s12936-015-0999-2.

8.

Enantiomerically pure amino-alcohol quinolines: in vitro anti-malarial activity in combination with dihydroartemisinin, cytotoxicity and in vivo efficacy in a Plasmodium berghei mouse model.

Mullié C, Taudon N, Degrouas C, Jonet A, Pascual A, Agnamey P, Sonnet P.

Malar J. 2014 Oct 16;13:407. doi: 10.1186/1475-2875-13-407.

9.

Identifying rapidly parasiticidal anti-malarial drugs using a simple and reliable in vitro parasite viability fast assay.

Linares M, Viera S, Crespo B, Franco V, Gómez-Lorenzo MG, Jiménez-Díaz MB, Angulo-Barturen Í, Sanz LM, Gamo FJ.

Malar J. 2015 Nov 5;14:441. doi: 10.1186/s12936-015-0962-2.

10.

Activity of benzothiazoles and chemical derivatives on Plasmodium falciparum.

Hout S, Azas N, Darque A, Robin M, Di Giorgio C, Gasquet M, Galy J, Timon-David P.

Parasitology. 2004 Nov;129(Pt 5):525-35.

PMID:
15552398
11.

Development of cultured Plasmodium falciparum blood-stage malaria cell banks for early phase in vivo clinical trial assessment of anti-malaria drugs and vaccines.

Stanisic DI, Liu XQ, De SL, Batzloff MR, Forbes T, Davis CB, Sekuloski S, Chavchich M, Chung W, Trenholme K, McCarthy JS, Li T, Sim BK, Hoffman SL, Good MF.

Malar J. 2015 Apr 7;14:143. doi: 10.1186/s12936-015-0663-x.

12.

A lactate dehydrogenase ELISA-based assay for the in vitro determination of Plasmodium berghei sensitivity to anti-malarial drugs.

Orjuela-Sánchez P, Duggan E, Nolan J, Frangos JA, Carvalho LJ.

Malar J. 2012 Nov 5;11:366. doi: 10.1186/1475-2875-11-366.

13.

Protective activity of biflavanones from Garcinia kola against Plasmodium infection.

Konziase B.

J Ethnopharmacol. 2015 Aug 22;172:214-8. doi: 10.1016/j.jep.2015.06.038. Epub 2015 Jun 27.

PMID:
26129936
14.

Trisubstituted Pyrimidines as Efficacious and Fast-Acting Antimalarials.

Norcross NR, Baragaña B, Wilson C, Hallyburton I, Osuna-Cabello M, Norval S, Riley J, Stojanovski L, Simeons FR, Porzelle A, Grimaldi R, Wittlin S, Duffy S, Avery VM, Meister S, Sanz L, Jiménez-Díaz B, Angulo-Barturen I, Ferrer S, Martínez MS, Gamo FJ, Frearson JA, Gray DW, Fairlamb AH, Winzeler EA, Waterson D, Campbell SF, Willis P, Read KD, Gilbert IH.

J Med Chem. 2016 Jul 14;59(13):6101-20. doi: 10.1021/acs.jmedchem.6b00028. Epub 2016 Jun 17.

15.

Anti-malarial activities of Andrographis paniculata and Hedyotis corymbosa extracts and their combination with curcumin.

Mishra K, Dash AP, Swain BK, Dey N.

Malar J. 2009 Feb 12;8:26. doi: 10.1186/1475-2875-8-26.

16.

In vivo and in vitro antimalarial activity of 4-nerolidylcatechol.

Rocha E Silva LF, Silva Pinto AC, Pohlit AM, Quignard EL, Vieira PP, Tadei WP, Chaves FC, Samonek JF, Lima CA, Costa MR, Alecrim Md, Andrade-Neto VF.

Phytother Res. 2011 Aug;25(8):1181-8. doi: 10.1002/ptr.3424. Epub 2011 Feb 8.

PMID:
21302338
17.
18.

In vitro and in vivo antimalarial activity of amphiphilic naphthothiazolium salts with amine-bearing side chains.

Ulrich P, Gipson GR, Clark MA, Tripathi A, Sullivan DJ Jr, Cerami C.

Am J Trop Med Hyg. 2014 Oct;91(4):824-32. doi: 10.4269/ajtmh.13-0565. Epub 2014 Sep 2.

19.

Fast in vitro methods to determine the speed of action and the stage-specificity of anti-malarials in Plasmodium falciparum.

Le Manach C, Scheurer C, Sax S, Schleiferböck S, Cabrera DG, Younis Y, Paquet T, Street L, Smith P, Ding XC, Waterson D, Witty MJ, Leroy D, Chibale K, Wittlin S.

Malar J. 2013 Nov 16;12:424. doi: 10.1186/1475-2875-12-424.

20.

Novel 4-aminoquinoline analogs highly active against the blood and sexual stages of Plasmodium in vivo and in vitro.

Sáenz FE, Mutka T, Udenze K, Oduola AM, Kyle DE.

Antimicrob Agents Chemother. 2012 Sep;56(9):4685-92. doi: 10.1128/AAC.01061-12. Epub 2012 Jun 18.

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