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Necrostatin-1 reduces neurovascular injury after intracerebral hemorrhage.

King MD, Whitaker-Lea WA, Campbell JM, Alleyne CH Jr, Dhandapani KM.

Int J Cell Biol. 2014;2014:495817. doi: 10.1155/2014/495817. Epub 2014 Mar 6.


TNF-alpha receptor antagonist, R-7050, improves neurological outcomes following intracerebral hemorrhage in mice.

King MD, Alleyne CH Jr, Dhandapani KM.

Neurosci Lett. 2013 May 10;542:92-6. doi: 10.1016/j.neulet.2013.02.051. Epub 2013 Mar 7.


Attenuation of hematoma size and neurological injury with curcumin following intracerebral hemorrhage in mice.

King MD, McCracken DJ, Wade FM, Meiler SE, Alleyne CH Jr, Dhandapani KM.

J Neurosurg. 2011 Jul;115(1):116-23. doi: 10.3171/2011.2.JNS10784. Epub 2011 Mar 18.


Necrostatin-1 ameliorates intracerebral hemorrhage-induced brain injury in mice through inhibiting RIP1/RIP3 pathway.

Su X, Wang H, Kang D, Zhu J, Sun Q, Li T, Ding K.

Neurochem Res. 2015 Apr;40(4):643-50. doi: 10.1007/s11064-014-1510-0. Epub 2015 Jan 10.


Anti-necroptosis chemical necrostatin-1 can also suppress apoptotic and autophagic pathway to exert neuroprotective effect in mice intracerebral hemorrhage model.

Chang P, Dong W, Zhang M, Wang Z, Wang Y, Wang T, Gao Y, Meng H, Luo B, Luo C, Chen X, Tao L.

J Mol Neurosci. 2014 Feb;52(2):242-9.


Acute and delayed protective effects of pharmacologically induced hypothermia in an intracerebral hemorrhage stroke model of mice.

Wei S, Sun J, Li J, Wang L, Hall CL, Dix TA, Mohamad O, Wei L, Yu SP.

Neuroscience. 2013 Nov 12;252:489-500. doi: 10.1016/j.neuroscience.2013.07.052. Epub 2013 Jul 30.


Intranasal delivery of hypoxia-preconditioned bone marrow-derived mesenchymal stem cells enhanced regenerative effects after intracerebral hemorrhagic stroke in mice.

Sun J, Wei ZZ, Gu X, Zhang JY, Zhang Y, Li J, Wei L.

Exp Neurol. 2015 Oct;272:78-87. doi: 10.1016/j.expneurol.2015.03.011. Epub 2015 Mar 20.


Tin-mesoporphyrin, a potent heme oxygenase inhibitor, for treatment of intracerebral hemorrhage: in vivo and in vitro studies.

Wagner KR, Hua Y, de Courten-Myers GM, Broderick JP, Nishimura RN, Lu SY, Dwyer BE.

Cell Mol Biol (Noisy-le-grand). 2000 May;46(3):597-608.


Systemic administration of urocortin after intracerebral hemorrhage reduces neurological deficits and neuroinflammation in rats.

Liew HK, Pang CY, Hsu CW, Wang MJ, Li TY, Peng HF, Kuo JS, Wang JY.

J Neuroinflammation. 2012 Jan 19;9:13. doi: 10.1186/1742-2094-9-13.


Necrostatin-1 reduces histopathology and improves functional outcome after controlled cortical impact in mice.

You Z, Savitz SI, Yang J, Degterev A, Yuan J, Cuny GD, Moskowitz MA, Whalen MJ.

J Cereb Blood Flow Metab. 2008 Sep;28(9):1564-73. doi: 10.1038/jcbfm.2008.44. Epub 2008 May 21.


Transient receptor potential canonical 3 inhibitor Pyr3 improves outcomes and attenuates astrogliosis after intracerebral hemorrhage in mice.

Munakata M, Shirakawa H, Nagayasu K, Miyanohara J, Miyake T, Nakagawa T, Katsuki H, Kaneko S.

Stroke. 2013 Jul;44(7):1981-7. doi: 10.1161/STROKEAHA.113.679332. Epub 2013 May 14.


Effects of Aquaporin-4 on edema formation following intracerebral hemorrhage.

Tang Y, Wu P, Su J, Xiang J, Cai D, Dong Q.

Exp Neurol. 2010 Jun;223(2):485-95. doi: 10.1016/j.expneurol.2010.01.015. Epub 2010 Feb 2.


Isoflurane posttreatment reduces brain injury after an intracerebral hemorrhagic stroke in mice.

Khatibi NH, Ma Q, Rolland W, Ostrowski R, Fathali N, Martin R, Applegate R, Stier G, Tang J, Zhang JH.

Anesth Analg. 2011 Aug;113(2):343-8. doi: 10.1213/ANE.0b013e31821f9524. Epub 2011 May 19.


NC1900, an arginine vasopressin analogue, fails to reduce brain edema and improve neurobehavioral deficits in an intracerebral hemorrhagic stroke mice model.

Manaenko A, Lekic T, Zhang JH, Tang J.

Acta Neurochir Suppl. 2011;111:155-9. doi: 10.1007/978-3-7091-0693-8_26.


Mouse models of intracerebral hemorrhage in ventricle, cortex, and hippocampus by injections of autologous blood or collagenase.

Zhu W, Gao Y, Chang CF, Wan JR, Zhu SS, Wang J.

PLoS One. 2014 May 15;9(5):e97423. doi: 10.1371/journal.pone.0097423. eCollection 2014.


Treatment with TO901317, a synthetic liver X receptor agonist, reduces brain damage and attenuates neuroinflammation in experimental intracerebral hemorrhage.

Wu CH, Chen CC, Lai CY, Hung TH, Lin CC, Chao M, Chen SF.

J Neuroinflammation. 2016 Mar 11;13(1):62. doi: 10.1186/s12974-016-0524-8.


Arginine-vasopressin V1a receptor inhibition improves neurologic outcomes following an intracerebral hemorrhagic brain injury.

Manaenko A, Fathali N, Khatibi NH, Lekic T, Hasegawa Y, Martin R, Tang J, Zhang JH.

Neurochem Int. 2011 Mar;58(4):542-8. doi: 10.1016/j.neuint.2011.01.018. Epub 2011 Jan 20.


Serine protease inhibitor attenuates intracerebral hemorrhage-induced brain injury and edema formation in rat.

Nakamura T, Kuroda Y, Hosomi N, Okabe N, Kawai N, Tamiya T, Xi G, Keep RF, Itano T.

Acta Neurochir Suppl. 2010;106:307-10. doi: 10.1007/978-3-211-98811-4_57.


17β-Estradiol attenuates hematoma expansion through estrogen receptor α/silent information regulator 1/nuclear factor-kappa b pathway in hyperglycemic intracerebral hemorrhage mice.

Zheng Y, Hu Q, Manaenko A, Zhang Y, Peng Y, Xu L, Tang J, Tang J, Zhang JH.

Stroke. 2015 Feb;46(2):485-91. doi: 10.1161/STROKEAHA.114.006372. Epub 2014 Dec 18.


Dimethyl fumarate confers neuroprotection by casein kinase 2 phosphorylation of Nrf2 in murine intracerebral hemorrhage.

Iniaghe LO, Krafft PR, Klebe DW, Omogbai EK, Zhang JH, Tang J.

Neurobiol Dis. 2015 Oct;82:349-58. doi: 10.1016/j.nbd.2015.07.001. Epub 2015 Jul 12.

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