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Items: 1 to 20 of 101

1.

Immunosuppression in acutely decompensated cirrhosis is mediated by prostaglandin E2.

O'Brien AJ, Fullerton JN, Massey KA, Auld G, Sewell G, James S, Newson J, Karra E, Winstanley A, Alazawi W, Garcia-Martinez R, Cordoba J, Nicolaou A, Gilroy DW.

Nat Med. 2014 May;20(5):518-23. doi: 10.1038/nm.3516. Epub 2014 Apr 13.

2.

Tying up PGE2 with albumin to relieve immunosuppression in cirrhosis.

Arroyo V, Moreau R.

Nat Med. 2014 May;20(5):467-9. doi: 10.1038/nm.3553. No abstract available.

PMID:
24804750
3.

Prostaglandin E2 -mediated immunosuppression and the role of albumin as its modulator.

Choe WH, Baik SK.

Hepatology. 2015 Mar;61(3):1080-2. doi: 10.1002/hep.27644. Epub 2015 Jan 28. No abstract available.

PMID:
25482406
4.

Cyclooxygenase-2, prostaglandin E2, and prostanoid receptor EP2 in fluid flow shear stress-mediated injury in the solitary kidney.

Srivastava T, Alon US, Cudmore PA, Tarakji B, Kats A, Garola RE, Duncan RS, McCarthy ET, Sharma R, Johnson ML, Bonewald LF, El-Meanawy A, Savin VJ, Sharma M.

Am J Physiol Renal Physiol. 2014 Dec 15;307(12):F1323-33. doi: 10.1152/ajprenal.00335.2014. Epub 2014 Sep 18.

5.
6.

Innate immunity: A COX detox for the immune system?

Bordon Y.

Nat Rev Immunol. 2014 Jun;14(6):358. doi: 10.1038/nri3686. Epub 2014 May 6. No abstract available.

PMID:
24798368
7.

Ketoprofen impairs immunosuppression induced by severe sepsis and reveals an important role for prostaglandin E2.

Brogliato AR, Antunes CA, Carvalho RS, Monteiro AP, Tinoco RF, Bozza MT, Canetti C, Peters-Golden M, Kunkel SL, Vianna-Jorge R, Benjamim CF.

Shock. 2012 Dec;38(6):620-9. doi: 10.1097/SHK.0b013e318272ff8a.

PMID:
23143054
8.

E prostanoid 2 (EP2)/EP4-mediated suppression of antigen-specific human T-cell responses by prostaglandin E2.

Okano M, Sugata Y, Fujiwara T, Matsumoto R, Nishibori M, Shimizu K, Maeda M, Kimura Y, Kariya S, Hattori H, Yokoyama M, Kino K, Nishizaki K.

Immunology. 2006 Jul;118(3):343-52.

9.

Suppression of inflammation with conditional deletion of the prostaglandin E2 EP2 receptor in macrophages and brain microglia.

Johansson JU, Pradhan S, Lokteva LA, Woodling NS, Ko N, Brown HD, Wang Q, Loh C, Cekanaviciute E, Buckwalter M, Manning-Bog AB, Andreasson KI.

J Neurosci. 2013 Oct 2;33(40):16016-32. doi: 10.1523/JNEUROSCI.2203-13.2013.

10.

Prostaglandin E2 suppresses poly I: C-stimulated cytokine production via EP2 and EP3 in immortalized human corneal epithelial cells.

Ueta M, Matsuoka T, Sotozono C, Kinoshita S.

Cornea. 2012 Nov;31(11):1294-8. doi: 10.1097/ICO.0b013e318242fd7c.

PMID:
22475642
11.

CD40 engagement on dendritic cells induces cyclooxygenase-2 and EP2 receptor via p38 and ERK MAPKs.

Harizi H, Limem I, Gualde N.

Immunol Cell Biol. 2011 Feb;89(2):275-82. doi: 10.1038/icb.2010.94. Epub 2010 Aug 10.

PMID:
20697426
12.

Prostaglandin E2 Inhibits NLRP3 Inflammasome Activation through EP4 Receptor and Intracellular Cyclic AMP in Human Macrophages.

Sokolowska M, Chen LY, Liu Y, Martinez-Anton A, Qi HY, Logun C, Alsaaty S, Park YH, Kastner DL, Chae JJ, Shelhamer JH.

J Immunol. 2015 Jun 1;194(11):5472-87. doi: 10.4049/jimmunol.1401343. Epub 2015 Apr 27.

13.

Microsomal prostaglandin E synthase-1 deficiency exacerbates pulmonary fibrosis induced by bleomycin in mice.

Wei B, Cai L, Sun D, Wang Y, Wang C, Chai X, Xie F, Su M, Ding F, Liu J, Yang J, Guan Y, Liu X.

Molecules. 2014 Apr 21;19(4):4967-85. doi: 10.3390/molecules19044967.

14.

Low E-prostanoid 2 receptor levels and deficient induction of the IL-1β/IL-1 type I receptor/COX-2 pathway: Vicious circle in patients with aspirin-exacerbated respiratory disease.

Machado-Carvalho L, Martín M, Torres R, Gabasa M, Alobid I, Mullol J, Pujols L, Roca-Ferrer J, Picado C.

J Allergy Clin Immunol. 2016 Jan;137(1):99-107.e7. doi: 10.1016/j.jaci.2015.09.028. Epub 2015 Nov 10.

PMID:
26560040
15.

Role of the prostaglandin E2/E-prostanoid 2 receptor signalling pathway in TGFβ-induced mice mesangial cell damage.

Li NN, Xu YY, Chen XL, Fan YP, Wu JH.

Biosci Rep. 2014 Dec 12;34(6):e00159. doi: 10.1042/BSR20140130.

16.

Hypermethylation of PTGER2 confers prostaglandin E2 resistance in fibrotic fibroblasts from humans and mice.

Huang SK, Fisher AS, Scruggs AM, White ES, Hogaboam CM, Richardson BC, Peters-Golden M.

Am J Pathol. 2010 Nov;177(5):2245-55. doi: 10.2353/ajpath.2010.100446. Epub 2010 Oct 1.

17.

PGE2 Inhibits IL-10 Production via EP2-Mediated β-Arrestin Signaling in Neuroinflammatory Condition.

Chu CH, Chen SH, Wang Q, Langenbach R, Li H, Zeldin D, Chen SL, Wang S, Gao H, Lu RB, Hong JS.

Mol Neurobiol. 2015 Aug;52(1):587-600. doi: 10.1007/s12035-014-8889-0. Epub 2014 Sep 14.

18.

Modulation of host natural killer cell functions in breast cancer via prostaglandin E2 receptors EP2 and EP4.

Holt DM, Ma X, Kundu N, Collin PD, Fulton AM.

J Immunother. 2012 Feb-Mar;35(2):179-88. doi: 10.1097/CJI.0b013e318247a5e9.

19.

Prostaglandin receptor EP2 is responsible for cyclooxygenase-2 induction by prostaglandin E2 in mouse skin.

Ansari KM, Sung YM, He G, Fischer SM.

Carcinogenesis. 2007 Oct;28(10):2063-8. Epub 2007 Feb 2.

PMID:
17277233
20.

Possible involvement of brain prostaglandin E2 and prostanoid EP3 receptors in prostaglandin E2 glycerol ester-induced activation of central sympathetic outflow in the rat.

Shimizu T, Tanaka K, Nakamura K, Taniuchi K, Yawata T, Higashi Y, Ueba T, Dimitriadis F, Shimizu S, Yokotani K, Saito M.

Neuropharmacology. 2014 Jul;82:19-27. doi: 10.1016/j.neuropharm.2014.03.005. Epub 2014 Mar 19.

PMID:
24657150

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