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The effect of prolonged exposure to morphine on canine cerebral 5-HT2A receptors measured with (123)I-R91150 SPECT.

Adriaens A, Polis I, Vermeire S, Waelbers T, Croubels S, Duchateau L, Van Dorpe S, Eersels J, De Spiegeleer B, Peremans K.

Eur Neuropsychopharmacol. 2014 Jul;24(7):1133-8. doi: 10.1016/j.euroneuro.2014.03.004. Epub 2014 Mar 26.


The influence of morphine on cerebral 5-HT2A availability in dogs: a SPECT study.

Adriaens AM, Polis IE, Vermeire ST, Waelbers T, Duchateau L, Sys SU, Van Dorpe S, Eersels JL, De Spiegeleer B, Peremans K.

J Nucl Med. 2012 Dec;53(12):1969-73. doi: 10.2967/jnumed.112.103796. Epub 2012 Oct 22.


5-HT2A receptors in the feline brain: 123I-5-I-R91150 kinetics and the influence of ketamine measured with micro-SPECT.

Waelbers T, Polis I, Vermeire S, Dobbeleir A, Eersels J, De Spiegeleer B, Audenaert K, Slegers G, Peremans K.

J Nucl Med. 2013 Aug;54(8):1428-33. doi: 10.2967/jnumed.112.114637. Epub 2013 Jul 2.


Evaluation of the brain 5-HT2A receptor binding index in dogs with anxiety disorders, measured with 123I-5I-R91150 and SPECT.

Vermeire ST, Audenaert KR, Dobbeleir AA, De Meester RH, De Vos FJ, Peremans KY.

J Nucl Med. 2009 Feb;50(2):284-9. doi: 10.2967/jnumed.108.055731. Epub 2009 Jan 21.


Neuro-imaging the serotonin 2A receptor as a valid biomarker for canine behavioural disorders.

Vermeire S, Audenaert K, De Meester R, Vandermeulen E, Waelbers T, De Spiegeleer B, Eersels J, Dobbeleir A, Peremans K.

Res Vet Sci. 2011 Dec;91(3):465-72. doi: 10.1016/j.rvsc.2010.09.021. Epub 2010 Nov 3.


Decreased 5-HT2a receptor binding in patients with anorexia nervosa.

Audenaert K, Van Laere K, Dumont F, Vervaet M, Goethals I, Slegers G, Mertens J, van Heeringen C, Dierckx RA.

J Nucl Med. 2003 Feb;44(2):163-9.


Estimates of regional cerebral blood flow and 5-HT2A receptor density in impulsive, aggressive dogs with 99mTc-ECD and 123I-5-I-R91150.

Peremans K, Audenaert K, Coopman F, Blanckaert P, Jacobs F, Otte A, Verschooten F, van Bree H, van Heeringen K, Mertens J, Slegers G, Dierckx R.

Eur J Nucl Med Mol Imaging. 2003 Nov;30(11):1538-46. Epub 2003 Jul 3.


Effects of aging on brain perfusion and serotonin-2A receptor binding in the normal canine brain measured with single photon emission tomography.

Peremans K, Audenaert K, Blanckaert P, Jacobs F, Coopman F, Verschooten F, Van Bree H, Van Heeringen C, Mertens J, Slegers G, Dierckx R.

Prog Neuropsychopharmacol Biol Psychiatry. 2002 Dec;26(7-8):1393-404.


The effect of citalopram hydrobromide on 5-HT2A receptors in the impulsive-aggressive dog, as measured with 123I-5-I-R91150 SPECT.

Peremans K, Audenaert K, Hoybergs Y, Otte A, Goethals I, Gielen I, Blankaert P, Vervaet M, van Heeringen C, Dierckx R.

Eur J Nucl Med Mol Imaging. 2005 Jun;32(6):708-16.


Cortical serotonin 5-HT2A receptor binding and social communication in adults with Asperger's syndrome: an in vivo SPECT study.

Murphy DG, Daly E, Schmitz N, Toal F, Murphy K, Curran S, Erlandsson K, Eersels J, Kerwin R, Ell P, Travis M.

Am J Psychiatry. 2006 May;163(5):934-6.


The acute and chronic effects of MDMA ("ecstasy") on cortical 5-HT2A receptors in rat and human brain.

Reneman L, Endert E, de Bruin K, Lavalaye J, Feenstra MG, de Wolff FA, Booij J.

Neuropsychopharmacology. 2002 Mar;26(3):387-96.


Characterization of the SPECT 5-HT2A receptor ligand 123I-R91150 in healthy volunteers: part 2--ketanserin displacement.

Catafau AM, Danus M, Bullich S, Nucci G, Llop J, Abanades S, Cunningham VJ, Eersels JL, Pavia J, Farre M.

J Nucl Med. 2006 Jun;47(6):929-37.


Serotonin 2A receptor, serotonin transporter and dopamine transporter alterations in dogs with compulsive behaviour as a promising model for human obsessive-compulsive disorder.

Vermeire S, Audenaert K, De Meester R, Vandermeulen E, Waelbers T, De Spiegeleer B, Eersels J, Dobbeleir A, Peremans K.

Psychiatry Res. 2012 Jan 30;201(1):78-87. doi: 10.1016/j.pscychresns.2011.06.006. Epub 2012 Jan 27.


Regional binding index of the radiolabeled selective 5-HT2A antagonist 123I-5-I-R91150 in the normal canine brain imaged with single photon emission computed tomography.

Peremans K, Audenaert K, Coopman F, Jacobs F, Dumont F, Slegers G, Verschooten F, van Bree H, Mertens J, Dierckx R.

Vet Radiol Ultrasound. 2003 May-Jun;44(3):344-51.


Cortical and subcortical 5-HT2A receptor binding in neuroleptic-naive first-episode schizophrenic patients.

Erritzoe D, Rasmussen H, Kristiansen KT, Frokjaer VG, Haugbol S, Pinborg L, Baaré W, Svarer C, Madsen J, Lublin H, Knudsen GM, Glenthoj BY.

Neuropsychopharmacology. 2008 Sep;33(10):2435-41. doi: 10.1038/sj.npp.1301656. Epub 2008 Feb 20.


Morphine desensitization, internalization, and down-regulation of the mu opioid receptor is facilitated by serotonin 5-hydroxytryptamine2A receptor coactivation.

Lopez-Gimenez JF, Vilaró MT, Milligan G.

Mol Pharmacol. 2008 Nov;74(5):1278-91. doi: 10.1124/mol.108.048272. Epub 2008 Aug 14.


Comparison of cortical 5-HT2A receptor binding in bulimia nervosa patients and healthy volunteers.

Goethals I, Vervaet M, Audenaert K, Van de Wiele C, Ham H, Vandecapelle M, Slegers G, Dierckx R, van Heeringen C.

Am J Psychiatry. 2004 Oct;161(10):1916-8.


Evaluation of serotonin-2A receptor occupancy with 123I-5-I-R91150 and single-photon emission tomography before and after low-dose pipamperone administration in the canine brain.

Peremans K, De Spiegeleer B, Buntinx E, Dobbeleir A, Vermeire S, Vandermeulen E, De Vos F, Megens A, Eersels J, Audenaert K.

Nucl Med Commun. 2008 Aug;29(8):724-9. doi: 10.1097/MNM.0b013e3282fdc989.


Alterations in 5-HT2A receptor signaling in male and female transgenic rats over-expressing either Gq or RGS-insensitive Gq protein.

Shi J, Damjanoska KJ, Zemaitaitis B, Garcia F, Carrasco G, Sullivan NR, She Y, Young KH, Battaglia G, Van De kar LD, Howland DS, Muma NA.

Neuropharmacology. 2006 Sep;51(3):524-35.


The effect of morphine on regional cerebral blood flow measured by 99mTc-ECD SPECT in dogs.

Adriaens A, Peremans K, Waelbers T, Vandermeulen E, Croubels S, Duchateau L, Dobbeleir A, Audenaert K, Eersels J, Vermeire S, De Spiegeleer B, Polis I.

PLoS One. 2014 Oct 8;9(10):e109680. doi: 10.1371/journal.pone.0109680. eCollection 2014.

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