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Items: 1 to 20 of 92

1.

The NS5A-binding heat shock proteins HSC70 and HSP70 play distinct roles in the hepatitis C viral life cycle.

Khachatoorian R, Ganapathy E, Ahmadieh Y, Wheatley N, Sundberg C, Jung CL, Arumugaswami V, Raychaudhuri S, Dasgupta A, French SW.

Virology. 2014 Apr;454-455:118-27. doi: 10.1016/j.virol.2014.02.016. Epub 2014 Feb 28.

2.

Allosteric heat shock protein 70 inhibitors block hepatitis C virus assembly.

Khachatoorian R, Riahi R, Ganapathy E, Shao H, Wheatley NM, Sundberg C, Jung CL, Ruchala P, Dasgupta A, Arumugaswami V, Gestwicki JE, French SW.

Int J Antimicrob Agents. 2016 Apr;47(4):289-96. doi: 10.1016/j.ijantimicag.2016.01.012. Epub 2016 Mar 2.

3.

Heat shock protein 70 is associated with CSFV NS5A protein and enhances viral RNA replication.

Zhang C, Kang K, Ning P, Peng Y, Lin Z, Cui H, Cao Z, Wang J, Zhang Y.

Virology. 2015 Aug;482:9-18. doi: 10.1016/j.virol.2015.02.014. Epub 2015 Mar 30.

4.

The heat shock protein inhibitor Quercetin attenuates hepatitis C virus production.

Gonzalez O, Fontanes V, Raychaudhuri S, Loo R, Loo J, Arumugaswami V, Sun R, Dasgupta A, French SW.

Hepatology. 2009 Dec;50(6):1756-64. doi: 10.1002/hep.23232.

5.

A cell-permeable hairpin peptide inhibits hepatitis C viral nonstructural protein 5A-mediated translation and virus production.

Khachatoorian R, Arumugaswami V, Ruchala P, Raychaudhuri S, Maloney EM, Miao E, Dasgupta A, French SW.

Hepatology. 2012 Jun;55(6):1662-72. doi: 10.1002/hep.25533. Epub 2012 Jan 30.

6.

The lysine methyltransferase SMYD3 interacts with hepatitis C virus NS5A and is a negative regulator of viral particle production.

Eberle CA, Zayas M, Stukalov A, Pichlmair A, Alvisi G, Müller AC, Bennett KL, Bartenschlager R, Superti-Furga G.

Virology. 2014 Aug;462-463:34-41. doi: 10.1016/j.virol.2014.05.016. Epub 2014 Jun 14.

7.

Involvement of hepatitis C virus NS5A hyperphosphorylation mediated by casein kinase I-α in infectious virus production.

Masaki T, Matsunaga S, Takahashi H, Nakashima K, Kimura Y, Ito M, Matsuda M, Murayama A, Kato T, Hirano H, Endo Y, Lemon SM, Wakita T, Sawasaki T, Suzuki T.

J Virol. 2014 Jul;88(13):7541-55. doi: 10.1128/JVI.03170-13. Epub 2014 Apr 23.

8.

Essential role of domain III of nonstructural protein 5A for hepatitis C virus infectious particle assembly.

Appel N, Zayas M, Miller S, Krijnse-Locker J, Schaller T, Friebe P, Kallis S, Engel U, Bartenschlager R.

PLoS Pathog. 2008 Mar 28;4(3):e1000035. doi: 10.1371/journal.ppat.1000035.

9.

Phosphatidylserine-specific phospholipase A1 involved in hepatitis C virus assembly through NS2 complex formation.

Guo M, Pei R, Yang Q, Cao H, Wang Y, Wu C, Chen J, Zhou Y, Hu X, Lu M, Chen X.

J Virol. 2015 Feb;89(4):2367-77. doi: 10.1128/JVI.02982-14. Epub 2014 Dec 10.

10.

Nonstructural 5A Protein of Hepatitis C Virus Regulates Soluble Resistance-Related Calcium-Binding Protein Activity for Viral Propagation.

Tran GV, Luong TT, Park EM, Kim JW, Choi JW, Park C, Lim YS, Hwang SB.

J Virol. 2015 Dec 30;90(6):2794-805. doi: 10.1128/JVI.02493-15.

11.

Hepatitis C Virus Particle Assembly Involves Phosphorylation of NS5A by the c-Abl Tyrosine Kinase.

Yamauchi S, Takeuchi K, Chihara K, Sun X, Honjoh C, Yoshiki H, Hotta H, Sada K.

J Biol Chem. 2015 Sep 4;290(36):21857-64. doi: 10.1074/jbc.M115.666859. Epub 2015 Jul 22.

12.

Physical and functional interaction between hepatitis C virus NS5A protein and ovarian tumor protein deubiquitinase 7B.

Sianipar IR, Matsui C, Minami N, Gan X, Deng L, Hotta H, Shoji I.

Microbiol Immunol. 2015 Aug;59(8):466-76. doi: 10.1111/1348-0421.12278.

13.

Regulation of hepatitis C virion production via phosphorylation of the NS5A protein.

Tellinghuisen TL, Foss KL, Treadaway J.

PLoS Pathog. 2008 Mar 21;4(3):e1000032. doi: 10.1371/journal.ppat.1000032.

14.

Y-Box Binding Protein 1 Stabilizes Hepatitis C Virus NS5A via Phosphorylation-Mediated Interaction with NS5A To Regulate Viral Propagation.

Wang WT, Tsai TY, Chao CH, Lai BY, Wu Lee YH.

J Virol. 2015 Nov;89(22):11584-602. doi: 10.1128/JVI.01513-15. Epub 2015 Sep 9.

15.

Cucumber Necrosis Virus Recruits Cellular Heat Shock Protein 70 Homologs at Several Stages of Infection.

Alam SB, Rochon D.

J Virol. 2015 Dec 30;90(7):3302-17. doi: 10.1128/JVI.02833-15.

16.

Polo-like kinase 1 is involved in hepatitis C virus replication by hyperphosphorylating NS5A.

Chen YC, Su WC, Huang JY, Chao TC, Jeng KS, Machida K, Lai MM.

J Virol. 2010 Aug;84(16):7983-93. doi: 10.1128/JVI.00068-10. Epub 2010 Jun 9.

17.

Apolipoprotein J, a glucose-upregulated molecular chaperone, stabilizes core and NS5A to promote infectious hepatitis C virus virion production.

Lin CC, Tsai P, Sun HY, Hsu MC, Lee JC, Wu IC, Tsao CW, Chang TT, Young KC.

J Hepatol. 2014 Nov;61(5):984-93. doi: 10.1016/j.jhep.2014.06.026. Epub 2014 Jul 1.

PMID:
24996046
18.

Nonstructural 5A protein of hepatitis C virus regulates heat shock protein 72 for its own propagation.

Lim YS, Shin KS, Oh SH, Kang SM, Won SJ, Hwang SB.

J Viral Hepat. 2012 May;19(5):353-63. doi: 10.1111/j.1365-2893.2011.01556.x. Epub 2011 Nov 21.

PMID:
22497815
19.

Heat shock protein 72 is associated with the hepatitis C virus replicase complex and enhances viral RNA replication.

Chen YJ, Chen YH, Chow LP, Tsai YH, Chen PH, Huang CY, Chen WT, Hwang LH.

J Biol Chem. 2010 Sep 3;285(36):28183-90. doi: 10.1074/jbc.M110.118323. Epub 2010 Jul 2.

20.

The lipid kinase phosphatidylinositol-4 kinase III alpha regulates the phosphorylation status of hepatitis C virus NS5A.

Reiss S, Harak C, Romero-Brey I, Radujkovic D, Klein R, Ruggieri A, Rebhan I, Bartenschlager R, Lohmann V.

PLoS Pathog. 2013 May;9(5):e1003359. doi: 10.1371/journal.ppat.1003359. Epub 2013 May 9.

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