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Items: 1 to 20 of 95


A systematic comparison of the anti-tumoural activity and toxicity of the three Adv-TKs.

Gao Q, Chen C, Ji T, Wu P, Han Z, Fang H, Li F, Liu Y, Hu W, Gong D, Zhang Z, Wang S, Zhou J, Ma D.

PLoS One. 2014 Apr 10;9(4):e94050. doi: 10.1371/journal.pone.0094050. eCollection 2014. Erratum in: PLoS One. 2016;11(4):e0153540.


Novel permissive murine immunocompetent orthotopic colon carcinoma model for comparison of the antitumoral and safety profiles of three Adv-TKs.

Chen C, Fang H, Han Z, Ye F, Ji T, Gong D, Li F, Zhou J, Ma D, Gao Q.

Gene Ther. 2014 Nov;21(11):975-83. doi: 10.1038/gt.2014.79. Epub 2014 Sep 4. Erratum in: Gene Ther. 2015 Mar;22(3):70.


Chapter three--Syrian hamster as an animal model to study oncolytic adenoviruses and to evaluate the efficacy of antiviral compounds.

Wold WS, Toth K.

Adv Cancer Res. 2012;115:69-92. doi: 10.1016/B978-0-12-398342-8.00003-3. Review.


In vivo gene therapy of ovarian cancer by adenovirus-mediated thymidine kinase gene transduction and ganciclovir administration.

Tong XW, Block A, Chen SH, Contant CF, Agoulnik I, Blankenburg K, Kaufman RH, Woo SL, Kieback DG.

Gynecol Oncol. 1996 May;61(2):175-9.


Safety and efficacy of VCN-01, an oncolytic adenovirus combining fiber HSG-binding domain replacement with RGD and hyaluronidase expression.

Rodríguez-García A, Giménez-Alejandre M, Rojas JJ, Moreno R, Bazan-Peregrino M, Cascalló M, Alemany R.

Clin Cancer Res. 2015 Mar 15;21(6):1406-18. doi: 10.1158/1078-0432.CCR-14-2213. Epub 2014 Nov 12.


HCCS1-armed, quadruple-regulated oncolytic adenovirus specific for liver cancer as a cancer targeting gene-viro-therapy strategy.

Xu HN, Huang WD, Cai Y, Ding M, Gu JF, Wei N, Sun LY, Cao X, Li HG, Zhang KJ, Liu XR, Liu XY.

Mol Cancer. 2011 Nov 1;10:133. doi: 10.1186/1476-4598-10-133.


A potent oncolytic adenovirus selectively blocks the STAT3 signaling pathway and potentiates cisplatin antitumor activity in ovarian cancer.

Han Z, Hong Z, Gao Q, Chen C, Hao Z, Ji T, Hu W, Yan Y, Feng J, Liao S, Wu P, Wang D, Wang S, Zhou J, Ma D.

Hum Gene Ther. 2012 Jan;23(1):32-45. doi: 10.1089/hum.2011.101. Epub 2011 Oct 14.


Syrian hamster tumor model to study oncolytic Ad5-based vectors.

Dhar D, Toth K, Wold WS.

Methods Mol Biol. 2012;797:53-63. doi: 10.1007/978-1-61779-340-0_4.


Therapeutic efficacy of an hTERT promoter-driven oncolytic adenovirus that expresses apoptin in gastric carcinoma.

Liu L, Wu W, Zhu G, Liu L, Guan G, Li X, Jin N, Chi B.

Int J Mol Med. 2012 Oct;30(4):747-54. doi: 10.3892/ijmm.2012.1077. Epub 2012 Jul 25.


Adenovirus-mediated suicide gene therapy for experimental bladder cancer.

Sutton MA, Berkman SA, Chen SH, Block A, Dang TD, Kattan MW, Wheeler TM, Rowley DR, Woo SL, Lerner SP.

Urology. 1997 Feb;49(2):173-80.


Combination effect of oncolytic adenovirus therapy and herpes simplex virus thymidine kinase/ganciclovir in hepatic carcinoma animal models.

Zheng FQ, Xu Y, Yang RJ, Wu B, Tan XH, Qin YD, Zhang QW.

Acta Pharmacol Sin. 2009 May;30(5):617-27. doi: 10.1038/aps.2009.33. Epub 2009 Apr 13.


Potent anti-tumor activity of telomerase-dependent and HSV-TK armed oncolytic adenovirus for non-small cell lung cancer in vitro and in vivo.

Zhang JF, Wei F, Wang HP, Li HM, Qiu W, Ren PK, Chen XF, Huang Q.

J Exp Clin Cancer Res. 2010 May 20;29:52. doi: 10.1186/1756-9966-29-52.


Persistent adenovirus-mediated thymidine kinase gene expression in ovarian cancer cells increases cell killing efficacy over time.

Kieback DG, Delvoux B, Romano A, Ollig S, Fischer DC.

Anticancer Res. 2008 Sep-Oct;28(5A):2569-75.


Treatment of malignant gliomas with a replicating adenoviral vector expressing herpes simplex virus-thymidine kinase.

Nanda D, Vogels R, Havenga M, Avezaat CJ, Bout A, Smitt PS.

Cancer Res. 2001 Dec 15;61(24):8743-50.


In vivo adenovirus-mediated suicide gene therapy of orthotopic bladder cancer.

Sutton MA, Freund CT, Berkman SA, Dang TD, Kattan MW, Wheeler TM, Rowley DR, Lerner SP.

Mol Ther. 2000 Sep;2(3):211-7.


Imaging adenoviral-mediated herpes virus thymidine kinase gene transfer and expression in vivo.

Tjuvajev JG, Chen SH, Joshi A, Joshi R, Guo ZS, Balatoni J, Ballon D, Koutcher J, Finn R, Woo SL, Blasberg RG.

Cancer Res. 1999 Oct 15;59(20):5186-93.

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